The Discrete Orthonormal Stockwell Transform (DOST) (Stockwell, 2007) projects a finite-length, periodically sampled signal onto a set of orthonormal basis vectors that are localized in time and scale such that all basis functions at each scale are represented by a finite number of Discrete Fourier Transform (DFT) basis functions. It is based on the Stockwell Transform (Stockwell et al., 1996), sometimes referred to as the S-transform, which is applicable to continuously defined waveforms. Furthermore, the DFT basis functions corresponding to each DOST scale are non-overlapping. The shorter DOST scales correspond to higher-frequency DFT basis functions and greater bandwidths than the longer DOST scales. Thus, the DOST is a type of time-frequency transform and is suitable for non-stationary time-series analysis. Additionally, the DOST of an N-point record can be calculated efficiently in order N log N operations (Wang and Orchard, 2009). Several applications of the S-transform and the DOST have been documented including beamforming with array data (Collar and Frazier, 2022; Frazier, 2022). In this presentation, the DOST used is to examine the statistics of data measured with infrasound sensors as a function of the DOST scales, adaptively characterize the amplitude distributions of the DOST coefficients at each scale and perform near-optimal detection of transient signals. Results corresponding to infrasound data recorded under various conditions are presented.