Online Portal Research Articles

Trust, Social Influence and Perceived Usefulness: Examining Online Purchase Intentions among Gen Z

The growing popularity of online shopping collides with user reservations related to trust, social influence, and perceived purchase usefulness, with such concerns acutely observable among Gen Z populations. As digital natives and prolific online users, Gen Z's purchasing patterns offer valuable insights for marketers adjusting their online strategies. This study extends the body of knowledge by examining the determinants of online purchase intentions among Gen Z thereby guiding university administrators, educators, and online retailers in crafting improved online shopping experiences. Utilizing a non-intrusive, naturalistic research setting, the study harnesses an anonymous survey methodology, and data is rigorously analyzed using Statistical Package for Social Science (SPSS). Findings indicate that trust and perceived usefulness are significantly connected to students' online purchasing decisions. This study enhances the theory of online buying habits by emphasizing trust and value in e-commerce. It advises adding trust cues and functional benefits to online portals, the key to influencing Gen Z buyers and boosting market expansion and e-shopper satisfaction.

Socioeconomic Disparities in Online Patient Portal Utilization Among Total Knee Arthroplasty Recipients

BackgroundSince 2021, the Centers for Medicare and Medicaid Services have mandated that patients have open access to their medical records. Many institutions use online portals, which allow patients to access their health information and communicate with care teams. Our research aimed to evaluate demographic patterns for online patient portal utilization in patients undergoing total knee arthroplasty (TKA). Further, we assessed if and how portal engagement contributes to perioperative outcomes. MethodsThis study retrospectively reviewed primary and elective TKA from 2017 to 2022 at a single academic institution. Patients were stratified into 2 groups based on their online portal status: activated (A) or not-activated (NA). Baseline characteristics and postoperative outcomes were collected from the electronic medical record and compared. ResultsIn total, 10,995 patients were included: 8,330 (75.8%) were A and 2,625 (24.2%) were NA. The NA group was significantly older (P < .001); more likely to be Black (P < .001), women (P < .001), single/divorced/widowed (P < .001), non-English speaking (P < .001), and Medicare or Medicaid insured (P < .001); from zip codes with median incomes below $50,000 (P < .001), and more likely to be American Society of Anesthesiologists class III or IV (P < .001). Patient-reported outcome measure completion rates were significantly lower in the NA group (15.3 versus 47.7%, P < .001). Lengths of stay (LOS) were significantly higher in the NA group (2.7 versus 2.1 days, P < .001). The NA group was significantly more likely to be discharged to skilled nursing facilities (P < .001). Comparable rates of 90-day emergency department visits, readmissions, as well as 90-day and 2-year revisions, were observed across groups. ConclusionsThere are significant disparities in online portal activation status based on patient demographics. Patients who have A portals had significantly higher Patient-reported outcome measure completion rates, shorter LOS, and higher rates of home discharge. Further research should determine which other factors may affect patient portal utilization and inform interventions to improve portal utilization among minority populations.

Patient perspectives on BCMA-targeted therapies for multiple myeloma: a survey conducted in a patient advocacy group.

Advances in multiple myeloma (MM) treatment have shifted the therapeutic landscape. Understanding patients' perspectives can assist physicians in helping patients make informed decisions. This study aimed to understand the patient decision-making process and gain insights into patient perspectives on B-cell maturation antigen (BCMA)-targeted therapies for MM. An 18-question survey was completed by patients with MM enrolled in HealthTree® Cure Hub, an online portal helping patients with plasma cell dyscrasias navigate their disease. From October 28, 2022, to January 12, 2023, 325 patients with MM participated in the survey. The mean age (standard deviation) of the respondents was 66 (8) years; 54% were female and 90% were White. Among 218 patients with complete clinical records in the database, the median (min, max) lines of therapy (LOT) was 2 (1,16). Among 61 (28%) patients who had received ≥4 LOTs, 55 (90%) were triple-class exposed. Of the 290 patients who responded to the question about openness to new therapies, 76 (26%) were open to trying a new therapy immediately and 125 (43%) wanted more information on safety and efficacy. Most respondents reported likely or very likely to try a BCMA CAR T-cell therapy (60%) or a bispecific antibody (74%) and some needed more information to decide (16% for CAR T-cell therapy and 13% for bispecific antibody). The most requested information included efficacy, side effects (SEs), eligibility, and administration process for both CAR T-cell and bispecific therapies. When 2 therapies with the same efficacy and duration of response were offered, 69% of respondents would prefer the therapy with a lower risk of severe SEs but requires continuous dosing with no treatment-free interval, and 31% preferred a therapy given once followed by a treatment-free interval but with a potentially higher risk of severe SEs. To receive an effective therapy, the top acceptable trade-offs included frequent monitoring of SEs and initiating a new therapy in a hospital setting, and the least acceptable compromise was caregiver burden. This study found a high level of openness in patients with MM to try BCMA-targeted therapies. Information on efficacy, safety, availability, and eligibility may assist patients on decision-making.

A survey of severe asthma in Canada: results from the CASCADE practice reflective program.

Since the last guidance was published by the Canadian Thoracic Society, there have been several advances in the clinical management of severe asthma. To gain a better understanding of the current standards of care and treatment patterns of patients, the CASCADE practice reflective program was established to conduct a real-world analysis of severe asthma management among specialists in Canada with a goal of identifying areas of opportunity to enhance patient management and outcomes. The CASCADE program was a two-part practice reflective and assessment program delivered through an on-line portal for selected specialists (Respirologists and Allergists) in Canada. The program consisted of a one-time overview survey of physician practice to establish overall practice parameters, followed by a review of at least 5 severe asthma patients to establish the current landscape of severe asthma management. The program collected practice overview surveys from 78 specialists (52 Respirologists, 24 Allergists, and 2 General practice physicians with an interest in respiratory disease) in 8 provinces. Practices included a variety of types in both large metropolitan centres and smaller regional settings. There were 503 patients reviewed and included in the program. Most (65%) patients were currently using a biologic treatment, 30% were biologic naive, and 5% had used a biologic treatment in the past. Most patients (53%) were reported to have mixed allergic and eosinophilic phenotypes, despite a perception that allergic, eosinophilic and mixed phenotypes were evenly balanced in the physician practice. Overall, patients currently treated with biologic agents had parameters suggesting higher control and were more satisfied with treatment. However, there was less than optimal treatment satisfaction for more than half of all patients, particularly for those patients not treated with a biologic agent. Phenotyping is hampered by poor availability for several assessments, and the full range of treatments are not currently fully utilized, partly due to physician familiarity with the agents and partly due to prescribing restrictions. Even when treated with biologic agents, patient satisfaction can still be improved.

EXPRESS: Mixing User- and Publisher-Generated Content: Quantifying UGC Spillover Effect in a Hybrid Content Environment

Publishers are increasingly turning to user-generated content (UGC) to supplement the content they produce. However, what is the relationship between the consumption of UGC and publisher-generated content (PGC)? Consumption of different types of UGC may have different effects, one creating a positive synergy with PGC consumption that nets more ad revenue, while another stymies PGC consumption and has adverse financial consequences. In this research, we empirically investigate content consumption in a hybrid content environment when publishers’ main revenue resource relies on traffic on PGC pages. Using data from a major online portal, we examine the spillover effect generated by different types of UGC, including how soon users are likely to return to the website and the type of content they are likely to consume. Although higher forum consumption promotes revisits and increased PGC consumption, blog and album consumption do not contribute positively to revisits and PGC consumption. We illustrate via simulations that one type of UGC may increase PGC consumption by 18% more than other types and that ignoring the UGC spillover effect can significantly affect the publisher’s monetization strategy. We quantify these spillover effects by UGC type and compare strategies for optimizing the mix of PGC and different types of UGC for monetization.

E Grampanchayat

E-Gram Panchayat leverages digital technologies to streamline and improve the efficiency of administrative processes within rural local self-government bodies. It enables the automation of various tasks and reduces paperwork. The use of technology ensures transparency in decision- making and resource allocation. Citizens can access information related to Panchayat activities, budgets, and projects online, fostering greater accountability among local representatives. E-Gram Panchayat platforms often include citizen-centric services, allowing villagers to participate in governance actively. This includes online grievance redressal systems and public feedback mechanisms. It enhances the delivery of essential public services such as birth and death certificates, land records, and social welfare schemes. These services become more accessible to rural residents through online portals

Measuring Transit Equity of an On-Demand Multimodal Transit System

Problem, research strategy, and findings On-demand transit is attracting the attention of transportation researchers and transit agencies for its potential to solve the first-mile/last-mile problem. Although on-demand transit has been proved to increase transit accessibility significantly, its impact on transit equity and equality has not been addressed. In this study we examined the potential impact of the On-Demand Multimodal Transit System (ODMTS) in Atlanta (GA), on both transit equity and equality compared with the existing transit system. The results showed that ODMTS could have a positive impact on transit equality by reducing the disparity in transit service between neighborhoods close to and far from the existing transit network; however, it may not improve transit equity. Takeaway for practice This study highlights the fact that improving transit service alone is not enough to create an equitable transportation environment, as accessibility is determined by both transportation and land use. Planners should consider interventions that address both factors, such as transit-oriented developments with affordable housing, to meaningfully tackle the inequities in transit accessibility. An interactive online portal for further exploration of various scenarios of accessibility changes in Atlanta and their impact on equity and equality is available at https://geospatial.gatech.edu/transit-equity.

Development of a Tool for Reporting Key Dietary Indicators from Sales Data in Remote Australian Aboriginal and Torres Strait Islander Community Stores.

Reporting key dietary indicators from sales data can help us guide store decision makers in developing effective store policy to support healthier customer purchases. We aimed to develop a web-based reporting tool of key dietary indicators from sales data to support health-promoting policy and practice in stores in geographically remote Aboriginal and Torres Strait Islander communities. Tool development included identifying key dietary indicators (informed by sales data from 31 stores), community consultation (19 Aboriginal and Torres Strait Islander store directors and two store managers) and a web-build. Tool evaluation involved feedback interviews with stakeholders (25 store managers and two nutritionists). Key dietary indicators aligned with Australian Dietary Guideline food groupings and recommendations. An online portal for accessing and customising reports was built. Stakeholder feedback indicated that the strengths of the reports were the visuals, ease of interpretation, providing information that was not currently available and potential to increase capacity to support healthy food retailing. Difficulties were defining healthiness classification with alignment to other nutrition guidelines used and ensuring reports reached relevant store decision makers. This tool may be valuable to support store decision makers in identifying and prioritising nutrition issues and optimising the health-enabling attributes of stores.

Enhancing Malware Detection Efficiency through CNN-Based Image Classification in a User-Friendly Web Portal

The proposed CNN-based malware detection web portal classifies images on a unique, self-made dataset to identify malware files as input. There are many different types of malware out there, but no method can detect them all. An anti-virus programme could be created that enforces malware image classification for the aforementioned scenarios as opposed to the traditional signature-based methods used by the majority of anti-virus programmes currently available in the market, which are time-consuming and ineffective because they rely just on signatures of previous malware attacks and need to be updated regularly. The fact that some malware is encrypted and requires a significant amount of computing power to decrypt makes this strategy ineffective for identifying all malware that accesses the network. As a result, fresh malware cannot be detected because this method simulates the behavior of malware samples and matches it to new programs. An online portal with a candid user interface will be used to deploy the proposed Deep-learning based malware detection algorithm. The file to be tested or classified will be uploaded onto the website

Rates of delirium referrals to the Neuropsychiatry Service in a tertiary referral centre hospital

IntroductionBeaumont Hospital is the National Neurosurgical Centre in Ireland. Due to the high numbers of referrals from Neurology and Neurosurgery, The Department of Psychiatry established a specialist Neuropsychiatry inpatient Liaison service and a weekly Neuropsychiatry outpatient clinic. Many of the referrals that the service receive involve the management of delirium. Delirium is a common medical complication, particularly in neurosurgical settings. Delirium causes significant symptom burden which can lead to distress to all involved and impacts quality of life.ObjectivesThe aim was to improve the rates of referrals for delirium presentations and referral rates overall from Neurology and Neurosurgery. The neuropsychiatry service have implemented a delirium protocol for all medical and surgical teams in Beaumont Hospital. This protocol can be accessed through the Beaumont hospital phone app, or on site on each ward. For this reason, delirium can be managed by medical teams in the first instance. If this is not successful, neuropsychiatry can be contacted for further advice or review of patients with more complicated presentations.MethodsThe neuropsychiatry service receives referrals through the Patient Information Profile Explorer system which is accessed through the Beaumont Hospital online portal. In the event of an urgent referral, neurology or neurosurgery teams can contact the neuropsychiatry service directly by phone. Referrals are logged on the team referral log book, and details of the referral are recorded along with diagnosis and management. Data was collected retrospectively from the PIPE and log book to measure the rates and reasons for referrals over a one year period. Rates and details of referrals were initially recorded between July-December 2022. An educational intervention was provided where psychoeducation was provided to junior hospital doctors during protected teaching times and further education was provided over the phone when referrals were discussed between team members. Rates and details of referrals were then recorded between January-July 2023.ResultsThere was a reduction in referrals when comparing the two six month periods. There were 115 neuropsychiatry referrals from July to December 2022 and 78 referrals from January to July 2023. Rates of delirium referrals also reduced from 31% to 25% after psychoeducation was provided to junior doctors.ConclusionsThis audit highlights the importance of communication and education for medical and surgical trainees in the management of delirium. There is a high rate of turnover of junior doctors throughout the year in Beaumont Hospital. For this reason, it is imperative that continued education is provided to allow them to follow the delirium protocol independently before seeking tertiary service assistance. Ultimately, early and rapid intervention of delirium can have a positive impact on patient care and prognosisDisclosure of InterestNone Declared

Lazertinib: A narrative drug review

ABSTRACT Epidermal growth factor receptor (EGFR) activating mutations are established drivers in non-small-cell lung cancer (NSCLC); 85% of these mutations are exon 19 deletion or exon 21 L858R point substitution. Lazertinib (YH-25448, JNJ-73841937, LECLAZA®) represents one of the latest oral third-generation EGFR-tyrosine kinase inhibitor (TKI) binding irreversibly to the Cys797 residue in the adenosine triphosphate (ATP)-binding site of the EGFR kinase domain, with high selectivity for EGFR mutations including T790M. To write this narrative review, we searched online portals of ScienceDirect, PubMed, and Google Scholar and various websites such as the United States Food and Drug Administration (US-FDA) and UpToDate, using the search terms “Lazertinib,” “YH-25448,” “JNJ-73841937,” and “NSCLC.” We shortlisted 30 articles published between January 2021 and December 2023, of which we included 10 articles. This review elaborates on the indications for use, side effects and safety profile, drug interactions, and pharmacokinetics and dynamics. Key evidence that investigated the use of lazertinib has also been discussed.

Crime Registry Platform using Blockchain Ethereum and web3

Abstract: Criminal activities in India are on the rise, with many incidents going unreported. Despite the availability of an online portal for storing the First Information Reports (FIRs) handwritten FIRs always will remain common due to some of the traditional methods and practices. And probably in most cases, the complainants should personally visit the police stations in order to file a offense report. Crime and Criminal Tracking Network and Systems (CCTNS) was launched in 2010 for national wide e-governance, it will operates on a centralized system and it is particularly limited to some individual states. Therefore, there is a need for the decentralized solution in order to ensure failure of a single point and secure managing of criminal complaints from the unauthorized access.

Identifying and Addressing Disparities in Public Libraries with Bayesian Latent Variable Modeling

Public libraries are an essential public good. We ask: are urban library systems providing equitable service to all residents, in terms of the books they have access to and check out? If not, what causes disparities: heterogeneous book collections, resident behavior and access, and/or operational policies? Existing methods leverage only system-level outcome data (such as overall checkouts per branch), and so cannot distinguish between these factors. As a result, it is difficult to use their results to guide interventions to increase equitable access. We propose a Bayesian framework to characterize book checkout behavior across multiple branches of a library system, learning heterogeneous book popularity, overall branch demand, and usage of the online hold system, while controlling for book availability. In collaboration with the New York Public Library, we apply our framework to granular data consisting of over 400,000 checkouts during 2022. We first show that our model significantly out-performs baseline methods in predicting checkouts at the book-branch level. Next, we study spatial and socioeconomic disparities. We show that disparities are largely driven by disparate use of the online holds system, which allows library patrons to receive books from any other branch through an online portal. This system thus leads to a large outflow of popular books from branches in lower income neighborhoods to those in high income ones. Finally, we illustrate the use of our model and insights to quantify the impact of potential interventions, such as changing how books are internally routed between branches to fulfill hold requests.

An Indian epidemiological overview of ocular emergencies of the year 2022

Aim and objectiveThis study aimed to provide an epidemiological overview of the ocular emergencies that occurred in India in the year 2022. The study analyzed the demographic, clinical, and etiological characteristics of the patients who presented with ocular emergencies to various eye care facilities across the country. The study also evaluated the outcomes and complications of ocular emergencies and identified the risk factors and preventive measures for reducing their incidence and severity. MethodA retrospective study, we extracted data from the NPCBVI online portal Niramaya and calculated the frequency, percentage, and incidence rates of ocular emergencies by various demographic and geographic variables. ResultsMore males (55.9%) than females (44.1%) are blind in India. The age group with the highest frequency of blindness is 15–49 years (40%), followed by 50–69 years (30%), ≥70 years (20%) and <15 years (10%). Most of the blind people live in rural areas (70%), while only 30% live in urban areas. The states/UTs with the highest frequency of blindness are Uttar Pradesh (12.3%), Maharashtra (10.5%), Bihar (8.7%), West Bengal (7.4%) and Madhya Pradesh (6.8%). The remaining states/UTs account for 54.3% of the blind population. The most common causes of blindness are trauma (32.8%), infection/inflammation (34.5%) and glaucoma (24.7%). Other causes make up 8% of the total. ConclusionWe concluded that ocular emergencies are a significant public health problem in India and more research is needed to understand their epidemiology and management.

Multisensor Fuzzy Logic Approach for Enhanced Fire Detection in Smart Cities

As smart cities expand rapidly, the demand for strong fire protection has become even more essential. A significant challenge lies in ensuring that fire detection systems integrate seamlessly into our modern infrastructures. Leveraging multisensor systems can yield reliable data on potential fires. Particularly in smart buildings, the effectiveness of multisensor fire detection algorithms becomes paramount. This research introduces a fuzzy logic-driven method that harnesses the power of smoke, flame, and temperature sensors. While smoke, flames, and elevated temperatures are primary fire indicators, they can manifest concurrently or sequentially. We have amalgamated various fuzzy logic rules (IF-THEN structures) to gauge the intensity of fires. When a fire ignites, the sensors spring into action, identifying its source and promptly notifying users via the Internet and GSM modems. Moreover, they relay the fire’s precise geographic coordinates to fire departments. The fire’s status will be consistently updated on a dedicated online portal. It was observed from our results that the system proficiently sends fire alerts to residents, and the fire status undergoes regular updates at 45-second intervals. This refreshing is initiated by the identification of a designated percentage of smoke and flame. These outcomes validate the system’s effectiveness in enhancing the precision and responsiveness of fire detection capabilities.

The new digital archive at the Neanderthal Museum

The management and publication of digital data on online repositories constitutes a task that is becoming more and more relevant for museums and cultural heritage institutions alike. Not only is it important to archive the growing volume of data produced on a daily basis, but also to make this data available and reach out to old and new audience targets, such as fellow researchers, students, enthusiasts, in new and meaningful ways. The Neanderthal Museum, since two decades engaged in the development and establishment of a diversified digital offer, profiting from the recent completion of the DISAPALE project and its hundreds of newly scanned 3D models, has created a brand new online portal, planned as the core of its digital activity. The history of development (specifically the NESPOS portal), the issues encountered in the planning and realization phases (e.g. requirements for efficiency and long-term maintainability, freedom from previous dependencies on proprietary software), as well as the design decisions and technical solutions are critically discussed, highlighting strengths, weaknesses and possible future improvements. An introduction to the client-server architecture is provided, detailing the development of the back-end using a lightweight Java server component with integrated PostgreSQL relational database and the user-facing front-end built with modern web technologies to create a tailor-made, flexible and clutter-free web application. Finally a short look at the current status of scientific enterprises in digital archaeology is given, with a specific focus on the entanglements between museums, cultural heritage institutions and government entities.

EpiVar Browser: advanced exploration of epigenomics data under controlled access.

Human epigenomic data has been generated by large consortia for thousands of cell types to be used as a reference map of normal and disease chromatin states. Since epigenetic data contains potentially identifiable information, similarly to genetic data, most raw files generated by these consortia are stored in controlled-access databases. It is important to protect identifiable information, but this should not hinder secure sharing of these valuable datasets. Guided by the Framework for responsible sharing of genomic and health-related data from the Global Alliance for Genomics and Health (GA4GH), we have developed an approach and a tool to facilitate the exploration of epigenomics datasets' aggregate results, while filtering out identifiable information. Specifically, the EpiVar Browser allows a user to navigate an epigenetic dataset from a cohort of individuals and enables direct exploration of genotype-chromatin phenotype relationships. Because individual genotypes and epigenetic signal tracks are not directly accessible, and rather aggregated in the portal output, no identifiable data is released, yet the interface allows for dynamic genotype-epigenome interrogation. This approach has the potential to accelerate analyses that would otherwise require a lengthy multi-step approval process and provides a generalizable strategy to facilitate responsible access to sensitive epigenomics data. Online portal: https://computationalgenomics.ca/tools/epivar; EpiVar Browser source code: https://github.com/c3g/epivar-browser; bw-merge-window tool source code: https://github.com/c3g/bw-merge-window.

Association of Social Determinants with Patient-Reported Outcomes in Patients with Cancer.

Patient-reported outcome (PRO) scores have been utilized more frequently, but the relationship of PRO scores to determinants of health and social inequities has not been widely studied. Our goal was to determine the association of PRO scores with social determinants. All patients with a new cancer diagnosis who completed a PRO survey from 2020 to 2022 were included. The PRO survey recorded scores for depression, fatigue, pain interference and physical function. Higher depression, fatigue and pain scores indicated more distress. Higher physical condition scores indicated improved functionality. A total of 1090 patients were included. Married patients had significantly better individual PRO scores for each domain. Patients who were able to use the online portal to complete their survey also had better individual scores. Male patients and non-White patients had worse pain scores than female and White patients, respectively. Patients with prostate cancer had the best scores while patients with head and neck and lung cancer had the worst scores. PRO scores varied by cancer disease site and stage. Social support may act in combination with specific patient/tumor factors to influence PRO scores. These findings present opportunities to address patient support at institutional levels.

Advancing a WEF nexus security index for Alaska: an informed starting point for policy making

ABSTRACT Water, energy, and food (WEF) security has become a key area of research in sustainable development. Prompted by the United Nations’ Sustainable Development Goals, a large body of research highlights the inter-connectedness of WEF systems and the dangers of their siloed treatment. Simultaneously, more attention is being placed on the WEF security of remote populations in the Arctic, especially for areas like Alaska, where WEF insecurities are prevalent, yet obscured by national reporting. This research developed a WEF Nexus Security Index for the state of Alaska that can be used by policy-makers to consider plausible causes for regional inequalities and why some regions of Alaska, and not others are exposed to higher levels of WEF insecurity. Beyond the conceptual value of the index, an on-line Arctic WEF Nexus Security portal was developed that further enables policy-makers and community leaders to track changes in WEF security and monitor the effects stemming from future interventions, be they policy or technological in nature. By bridging nexus thinking and nexus doing, we hope to provide policy-makers with a novel and accessible tool for achieving WEF security in Alaska.

Eliciting parental preferences and values for the return of additional findings from genomic sequencing

Health economic evidence is needed to inform the design of high-value and cost-effective processes for returning genomic results from analyses for additional findings (AF). This study reports the results of a discrete-choice experiment designed to elicit preferences for the process of returning AF results from the perspective of parents of children with rare conditions and to estimate the value placed on AF analysis. Overall, 94 parents recruited within the Australian Genomics and Melbourne Genomics programmes participated in the survey, providing preferences in a total of 1128 choice scenarios. Statistically significant preferences were identified for the opportunity to change the choices made about AF; receiving positive AF in person from a genetic counsellor; timely access to a medical specialist and high-quality online resources; receiving automatic updates through a secure online portal if new information becomes available; and lower costs. For AF uptake rates ranging between 50–95%, the mean per person value from AF analysis was estimated at AU$450–$1700 (US$300–$1140). The findings enable the design of a value-maximising process of analysis for AF in rare-disease genomic sequencing.