One-time Success Rate Research Articles

Construction and management of PICC nursing team

Objective To study the application and management of PICC nursing team in the clinic . Methods Totals of 257 patients who were carried out PICC from November 2009 to October 2011 were classified into control group without management of PICC nursing team .The other 257 patients who experienced both the PICC and management of PICC nursing team from November 2011 to February 2013 were classified into intervention group .In the control group , PICC maintenance was undertaken by all nurses but the implementation of PICC was operated by a fixed nurse .In the intervention group , both the implementation and maintenance of PICC were undertaken by PICC nursing team .To compare respectively one-time success rate of PICC , related complications and satisfaction of patients to nursing job of the two groups .Results One-time success rate of the control group （71.6%） was lower than that of the intervention group （96.1%）, with a statistically significant difference（χ2 =57.01, P<0.01）; The rate of PICC-related complications occurrence in the control group was 20.6%, which was much higher than 6.2% in the intervention group , with a statistically significant difference （χ2 =22.92, P<0.01）;The satisfaction of patients in the control group was 74.7%, which was lower than 97.7%in the intervention group, with a statistically significant difference （χ2 =20.72,P <0.01）.Conclusions The management mode of PICC nursing team can improve the nursing quality , significantly reduce PICC related complications and improve the level of the nursing professional technology and the satisfaction of patients . Key words: PICC nursing team; Construction; Management

A highly effective TALEN-mediated approach for targeted gene disruption in Xenopus tropicalis and zebrafish

Transcription activator like effector nucleases (TALENs) is a promising approach to disrupt intended genomic loci. The assembly of highly effective TALENs is critical for successful genome editing. Recently we reported a convenient and robust platform to construct customized TALENs. The TALENs generated by this platform have been proven to be highly effective for gene disruption in Xenopus tropicalis and zebrafish as well as large genomic deletions in zebrafish. The one-time success rate of targeted gene disruption is about 90% for more than 100 genomic loci tested, with the mutation frequencies often reaching above 50%. Here we describe the validated protocol for TALEN assembly, methods for generating gene knockout animals in X. tropicalis and zebrafish, as well as the protocol for engineering large genomic deletions in zebrafish.

护理干预对子宫内膜癌磁共振扩散加权成像效果的影响分析

目的：探讨护理干预对子宫内膜癌磁共振扩散加权成像(DWI)效果的影响。方法：将60例行DWI检查的子宫内膜癌患者随机分为两组，对照组和护理干预组各30例。干预组采用全程护理干预，比较两组患者DWI检查的一次性成功率、DWI图像可诊断率和图像质量评分。结果：对照组和干预组患者DWI检查的一次性成功率分别为66.67%、96.67%，两组之间的差异有统计学意义(P Objective: To investigate the effect of nursing intervention on MR diffusion weighted imaging (DWI) with endometrial carcinoma. Methods: 60 patients with endometrial carcinoma were divided into two groups randomly: the nursing intervention group and control group. All the patients underwent MR DWI examination. The whole nursing intervention was proceeded in nursing intervention group. The results including one-time success rate, the scores of imaging quality and acceptable diagnostic rate of DWI images were compared between these two groups. Results: The one-time success rates in control group and nursing intervention group were 66.67% and 96.67% with statistic difference (P

Research of improved method and effects on implantable infusion port puncture fixing technique

Objective To discuss the improved method of implantable infusion port puncture fixing technique.Methods A total of 87 cases requiring implantable infusion port puncture maintenance patients were randomly divided into two groups,49 cases in experimental group used the improved four fingers to the fixed method of puncture,38 cases in the control group used the traditional three fingers to fixed puncture.The one-time success rate of puncture in two groups was evaluated.Results One-time success rate of puncture in the experimental group was higher than that in the control group.Conclusions The success rate of four fingers fixed puncture was significantly higher than that of three fingers fixing method.Four fingers fixation method is worth to popularize in the clinical application. Key words: Implantable infusion port; Puncture ; Technique

Comparison of the effect of ureteroscopic lithotripsy and extracorporeal shock wave lithotripsy for ureteral stones

Objective To compare the effect of ureteroscopic pneumatic lithotripsy(URL) and extracorporeal shock wave lithotripsy(ESWL) for ureteral stones.Methods 90 patients with ureteral stones were randomly divided into group A( URL group),group B( ESWL group),each group 45 cases.The effect of surgical treatment was compared between the two groups.Results The one-time success rate of gravel,stone free after 4 weeks of A group was significantly higher than that of group B( x2 =9.680,5.414,all P ＜0.05),but there was no significant difference in the surgical time and hospital stay of the two groups( t =1.010,0.909,all P ＞ 0.05 ).The postoperative renal colic,fever and other complications of group A were significantly lower than that of group B ( x2 =6.049,5.075,all P ＜0.05),but the gross heraturia and ureteral injury of group A was higher than that of group B(x2 =5.874,3.873,all P ＜ 0.05 ).Conclusion The ureteroscopic pneumatic lithotripsy and extracorporeal shock wave lithotripsy in the treatment of ureteral stones all have good effect,but ureteroscopic pneumatic lithotripsy and stone rubble drain success rate are significantly higher than extracorporeal shock wave lithotripsy,and postoperative complications are relatively less than extracorporeal shock wave lithotripsy. Key words: Ureteral stones; Ureteroscopic; Extracorporeal; Lithotripsy

The clinical application of video-laryngoscope in spontaneous respiration tracheal intubation

Objective To assess the safety and clinical values of video-laryngoscope in spontaneous respiration tracheal intubation for emergency patients. Methods Seventy-nine patients,who needed the endotracheal intubation,were recruited in our department between January 2010 and December 2010,and were randomly ( random number) divided into two groups according to consultative sequence.Forty patients (group A ) were operated with traditional laryngoscope and thirty-nine patients (group B ) with videolaryngoscope.The operative time and success rate of tracheal intubation,Cormack-Lehane classification,as well as adverse events,were recorded.The heart rate ( HR ),mean arterial blood pressure ( MAP),respiratory rate ( RR ),and saturation of pulse oxygen ( SpO2 ) were observed pre-operation,during operation and 2 min post-operation.Results ( 1 ) The Cormack-Lehane classification in group A were significantly lower than in group B. (2) The operative time of tracheal intubation in group B was significantly less than that in group A [(35.6+12.7) svs. (58.3 ± 13.5) s; P＜0.05] ; and one-time success rate of tracheal intubation in group B was higher than that in group A ( 84.6％ vs.52.5％ ; P ＜0.05).(3) Compared to group B,the HR and MAP in Group A were significantly increased at t2 and t3 ( P ＜ 0.05 ). ( 4 ) The adverse events,including restlessness,bucking and injury,were significantly decreased in group B than those in group A ( P ＜ 0.05 ).Conclusions The video-laryngoscope used in spontaneous respiration tracheal intubation,could improve Cormack-Lehane classification,short operative time,enhance one-time success rate and reduce adverse evevnts. Key words: Video-laryngoscope; Emergency ; Tracheal intubation; Cormack-lehane classification ; Complication

Virtual Assembly and Kinematic Simulation of Gear Form Grinding Machine Based on Pro/E

On the basis of establishing 3D modeling of gear form grinding machine, all levels of subassemblies of the grinding machine were assembled. Then the virtual assembly of total grinding machine was completed. Based on the kinematic simulation module of Pro/EMechanism, and combined with the virtual machine assembly model, the simulation analysis on machine movement was carried out. By simulating the actual working situation of the model, it could be checked whether the location, movement and load of the product could meet actual requirements before manufacturing the physical prototype of the product. This method is helpful for improving one-time success rate of new product development and saving product development cost.

Preliminary application of self-made acuductor of CT-guided aspiration biopsy for solitary pulmonary nodules

Sixty-four patients with solitary pulmonary nodules were included in this study. The diameter of pulmonary nodules was equal or less than 3.0 cm and no contact with the adjacent pleura. They were divided into study group( with acuductor locating method)and conventional group (with conventional method). The results showed that the one-time success rates were 97％ (31/32)in study group and 72％(23/32) in conventional group, the diagnostic accuracy were 94％ ( 30/32 ) and 88 ％ ( 28/32 ), respectively,while the successful puncture time were( 13. 5 ±4. 9)min and( 18. 7 ±5. 7) min, respectively. In study group,the complication rate was 9％ (3/32), while 28％ ( 9/32 ) in conventional group. There were statistical differences between the two groups. CT-guided aspriation biopsy for solitary pulmonary nodules with self-made acuductor can obviously improve one-time success rate and reduce the complication rate and operative time. Key words: CT-guided puncture; Coin lesion, pulmonary

The effectiveness analysis on the change of placing angle and method of urinary catheterization for male patients

Objective To improve the success rate of male patients' urinary catheterization and relieve their discomfort.Methods Sixty-eight male patients were randomly divided into two groups, conventional group and experimental group, each with 34 patients. Regular evaluation and disfection were taken and uniform double channel catheters were used in both groups. In conventional group, the cavernous body was hold lightly and raised to a 60-degree angle with the abdominal wall for catheterization. In experimental group, both sides of the cavemous body were fixed and pulled to a 90 °angle with the body longitudinal axis for catheterization . The success rate, tolerance, and hematuria situation of catheterization were observed and compared between both groups.Results The one-time success rate of catheterization in experimental group was significantly higher than that in conventional group.The discomforts like foreign body sensation and urinary reflex were significantly less in experimental group than those in conventional group.Conclusions Fixing the penis from both sides of the cavernous body and pulling the penis lightly to a 90 ° angle with the body longitudinal axis can improve the success rate of urinary catheterization, reduce complications and relieve patients' discomfort. Key words: Urinary catheterization; Angle; Method; Comfort

Comparison of three ways of venous sampling for infants

Objective To explore the best way of venous sampling for infants in order to improve onetime success rate and to reduce complications. Methods 151 infants were reviewed retrospectively who saw a doctor in clinic from March 2009 to March 2010, and patients were 4 days to 2 years old. They were divided into 3 groups randomly, and different method of venous sampling was applied to each group, then the one-time success rate and complication rate of three groups were compared. Results The method of femoral vein pit diagonal stabbing had a higher one-time success rate than the other two methods. however, the diffenences of success rates in three groups were not statistically significant (x2 = 3.02, P ＞ 0. 05). Conclusions Femoral vein pit diagonal stabbing method has several advantages, for instence, the position is easy to find, the method is fit for all infants,no matter fat or thin, it has a higher one-time success rate but lower complication rate, and so on. So this method is worthy spreading. Key words: Scalp vein; Femoral vein; Venous sampling; One-time success rate; Complication

Research in reason analysis and prevention of phlebitis caused by PICC in cancer patients undergoing chemotherapy

Objective To investigate the related factors of phlebitis caused by PICC and support effective preventive nursing measures. Methods 163 patients diagnosed as malignant tumor who first used peripherally inserted central catheters (PICC) were recruited. Patients were observed for 3 months. According to the diagnostic criterion of infection, 34 patients with phlebitis were divided into the phlebitis group and others were divided into the control group. All patients were investigated for general information survey :sex, age, tumor type, allergic history,location of inserted vein, one-time success rate,activity after catheter, elbow bending,phlebitis occurred time, grade and type. Laboratory markers:WBC,neutrophils,immune parameters, fasting plasma glucose. Trait anxiety inventory (T-AI)was used for assessment of emotional state. Case-control study between groups was carried out. Results The results of univariate analysis showed that location of inserted vein,times of inserting vein,activity of inserted limb,elbow bending,blood sugar level and emotion were associated with phlebitis. Sex, age, tumor type, allergic history, immune function,WBC,neutrophils were not involved with phlebitis. The results of multivariate logistic regression analysis showed that PICC through basilica vein was the protective factor. Multiple insertions, more activity of inserted limb,durative anxious emotion were the risk factors of phlebitis. Conclusions Different location of vein,times of inserting vein,activity of inserted limb,elbow bending,high blood glucose level and persistent anxious emotion are the risk factors of phlebitis. Taking effective preventive measures before,during, and after PICC can reduce the incidence of phlebitis. Key words: Malignant tumor; Chemotherapy; PICC; Phlebitis; Related factor; Prevent

Clinical study on the stomach tube insertion in the lateral recumbent position in rescuing the unconscious patients

Objective To study the application of stomach tube insertion in the lateral recumbent position in rescuing the unconscious patients,to reduce the discomfort of patients and increase the one-time success rate in the insertion of stomach tube. Methods 100 cases of unconscious patients were divided into the control group and the treatment group with 50 cases in each, they adopted routine tube insertion method and tube insertion in the lateral recumbent position.The success rate of tube insertion and incidence of complications were collected and analyzed in the two groups.Results The experimental group had a higher success rate and less complications compared with the control group.Conclusions The lateral recumbent position for stomach tube insertion is the ideal position for the unconscious patients. Key words: Unconscious patients; Stomach tube insertion in lateral recumbent position; Application study

A control study of two methods in oronasal conversion of nose biliary duct

Objective To compare the success rate, the one-time success rate, the average required time and the incidence of complications of two methods in oronasal conversion of nose biliary duct in naso-biliary drainage. Methods 60 cases of patients with ENBD in the ERCP in our department from March,2008 to March, 2010 were divided into the study group and the control group by random. The patients with sleeving the gastric tube by the guidewire during oronasal conversion of nose biliary duct were considered as the study group, and the patients using the traditional method were considered as the control group. The success rate of sleeving gastric tube, the one-time success rate of grasping, the average required time and the adverse reactions of the two groups were compared. Results The success rate of the study group was 100%, and the control group was 90%, there was no statistical significance. The one-time success rate of the study group was 76.7%, higher than 46.7% of the control group. The average required time of the study group were (1.3±0.3) min, shorter than (5.1±0.7) min of the control group. The incidence of complications in the study group were 13.3%, lower than 93.3% of the control group. Conclusions To sleeve the gastric tube by the guidewire can increase the one-time success rate of grasping the gastric tube, shorten time of grasping the gastric tube and significantly reduce discomfort of patients. Key words: Guidewire; Nose biliary duct; Drainage

Improvement of insertion of gastric lavage canal after tracheal intubation in patients with severe organophosphorns pesticide intoxication

Objective To improve the success rate of insertion of gastric lavage canal in patientswith tracheal intubation. Methods 70 patients with organophosphoms pesticide intoxication who neededgastric lavage after tracheal intubation were randomized into the test group and the control group, 35 easesin each. In test group, lavage canal was inserted through bite block orally and the bedside was raised till 70to 80 in angle. While in the control group, lavage canal was inserted directly through mouth with the posi-tion of hypsokinesis. The success rate of intubation was compared between the two groups. Results One-time success rate was 94.2% in the test group,which was statistically different from that of the control group(37.1%), P < 0.01. The complication of intubation in the test group was also lower than that of the controlgroup,which had statistical difference. Conclusions Through improvement of position to raise the bedsidetill 70 to 80 in angle, the insertion of gastric lavage canal through bite block orally was much better than thenormal one and it is worth applying. Key words: Tracheal Drug poison; Gastric canal; Nursing

Application of acupressure of Neiguan and Hegu point in gastric intubation

Objective To observe the effect of acupressure to relieve the adverse effect of patients and success rate of intubation during gastric tube insertion. Methods We divided 90 pancreatitis patients into the observation group and the control group randomly with 45 cases in each group.Routine intubation method was used in the control group.While in the observation group we gave acupressure of Neiguan and Hegu point based in the routine method.Then we compared the changes in heart rate,bucking,nausea,vomiting and other adverse effect as well as the one-time success rate of intubation.Results Changes in heart rate before and after intubation in the control group were significantly different(P 0.05).The incidence rate of adverse effect in the observation group was 4.4%and the one-time success rate of intubation was 97.8%.Conclusion It proved effective to use acupressure of Neiguan and Hegu point during gastric intubation for gastrointestinal decompression. Key words: Gastrointestinal decompression; Gastric intubation; Point; Acupressure

Contrast research for method of stomach tube indwelling for the NICU infant patients

目的 通过改变NICU患儿常规采用的胃管置入方法,以减少患儿置胃管过程中的痛苦和损害,提高置管成功率.方法将60例入住NICU、SpO2＞90%、需置胃管的患儿随机分为研究组和对照组,统计2种置管方法一次成功率、置管前后SpO2改变、采用DAN评分标准记录患儿疼痛表达得分.结果研究组一次成功率为100%,对照组一次成功率为66.6%.置管后较置管前研究组与对照组SpO2改变程度差异有显著性.2组DAN评分得分差异也有显著性.结论改良后的胃管置入法明显优于常规胃管置入法。