Obese Middle-aged Women Research Articles

The Effects of Qi-gong Exercise on Health-related Physical Fitness in Obese Middle-aged Women

The Effects of Qi-gong Exercise on Health-related Physical Fitness in Obese Middle-aged Women

The Effect of Walking Exercise on Physical Fitness and Serum Lipids in Obese Middle-aged Women: Pilot Study

[Purpose] This study was conducted to identify the effects of walking on the body composition, health-related physical fitness, and serum lipids as part of efforts to encourage middle-aged people to participate in walking as a regular and sustainable exercise. [Methods] This study was conducted as a pretest-posttest control group study. The study period was for 12 weeks from January to March 2010. The participants were 43 middle-aged women (age range: 40–55 years) with body fat rates over 30%. Subjects in the experiment group participated in the walking exercise (n = 38), the control group did not participate in the exercise (n = 23). [Results] In the exercise group, statistically significant reductions in weight and body fat were observed among the body composition measurement variables, and statistically significant increases in flexibility and cardiopulmonary endurance were observed among the physical fitness measurement variables. TC, TG, and LDL-C levels in the serum lipid measurement variables showed a statistically significant reduction in the exercise group. [Conclusion] The results of this study showed that 12 weeks of walking exercise influenced middle-aged women in a positive way by effecting changes in their body composition, physical fitness, and serum lipids. We believe that these positive changes result in positive effects on the factors for prevention of various adult diseases that can occur in middle-aged women.

A Study of Effect of the Compound Physical Activity Therapy on Muscular Strength in Obese Women

[Purpose] The aim of this study was to determine how compound physical activity affects muscular strength of middle-aged obese women. [Subjects] The research subjects were 40–50 year-old middle-aged women with excess body fat (30%). [Methods] The subjects were randomly assigned to two group, the experimental group and the control group. The experimental group performed two types of exercise programs for 16 weeks. Aerobic physical activity was performed 5 times per week, and anaerobic physical activity was performed every two days, and the exercise program each day was composed of a warm-up, the main exercise, and cooldown. The type of exercise focused on walking at a quick pace, and the intensity of the exercise focused on long periods of exercise at low intensity with the level of HRmax being 40–60%. The weight training, which was useful for beginners, as a type of kinetic load exercise, was applied with a composition recommended by the ACSM for muscle fitness (intensity of 40–60% of 1 RM and 10–15 repetitions). SPSS version 16.0 was used to analyze the data by ANCOVA and the t-test. [Results] The chest, leg, and abdominal strengths were significantly increased in the experimental group, and this indicates that compound physical activity is effective for improvement of muscular strength. [Conclusion] In conclusion, there were significant differences between groups in terms of muscular strength.

복합운동 프로그램이 복부비만 중년여성의 신체구성, 활동체력 및 심혈관계 질환 위험요소에 미치는 영향

복합운동 프로그램이 복부비만 중년여성의 신체구성, 활동체력 및 심혈관계 질환 위험요소에 미치는 영향

Oxidative stress and inflammatory responses following an acute bout of isokinetic exercise in obese women with knee osteoarthritis

BackgroundObesity is associated with osteoarthritis and it is accompanied by chronic inflammation and elevated oxidative stress. Strengthening-type exercise is used in knee osteoarthritis (KOA) rehabilitation. This study determined how acute isokinetic exercise influences inflammatory responses of obese middle-aged women with KOA. MethodsTen obese women with KOA and 10 age/weight-matched controls performed an isokinetic exercise protocol. Assessment of performance (knee extensor/flexor torque), muscle soreness (DOMS), knee flexibility (KJRM), and pain, and blood collection were performed pre-exercise, post-exercise, and at 24h post-exercise. Blood was analyzed for creatine kinase activity (CK), lactate dehydrogenase activity (LDH), CRP, leukocytes, uric acid, IL-6, TBARS, lipid hydroperoxides (LPX), protein carbonyls (PC), oxidized (GSH) and reduced glutathione (GSSG), total antioxidant capacity (TAC), catalase activity, and glutathione peroxidase activity (GPX). ResultsPhysical function remained unaltered by exercise (only torque at 90°/s decreased at 24h). Exercise increased DOMS throughout recovery but KJRM and pain remained unchanged. CK, LDH, and uric acid increased similarly in both groups. CRP remained unaffected by exercise while IL-6 increased only post-exercise. TBARS, PC, LPH, GSSG, and TAC increased only post-exercise in both groups. GSH and GSH/GSSG declined post-exercise and normalized thereafter. Catalase and GPX increased only in patients post-exercise. ConclusionIsokinetic exercise induces only a mild inflammatory response of very short duration (<24h) without affecting physical function and pain in KOA patients suggesting that moderate strengthening-type exercise may be safe for this patient cohort. These results indicate that KOA patients may be able to receive another exercise stimulus after only 48h. Clinical relevanceIsokinetic exercise produces minimal inflammation and pain in knee osteoarthritis patients, could be performed every 48h during rehabilitation, and up-regulates patients' antioxidant system.

Overweight and obese middle-aged women have increased risk of venous thromboembolism, particularly following surgery

Implications for practice and research: Obesity is associated with an increased risk of venous thromboembolism (VTE) including both spontaneous and postoperative events. Further research is needed regarding factors responsible for...

복싱에어로빅 참여가 비만 중년여성의 신체조성, 혈액성분 및 혈관탄성에 미치는 영향

본 연구는 12주간 비만 중년여성의 복싱에어로빅 운동프로그램 참여가 신체조성, 혈액성분 및 혈관탄성에 미치는 영향을 규명하기 위해 수행되었다. 본 연구의 대상자는 40세 이상의 중년여성으로 체지방율 30%이상 병역 상심혈관질환 및 대사성 질환이 없는 신체적으로 건강한 사람을 대상으로 복싱에어로빅 운동집단 8명과 통제집단 8명으로 무선배정(random assignment)으로 나누었으며, 복싱에어로빅 운동강도는 초기 1-4주는 HRmax 50%, 5-8주는 HRmax 60%, 9-12주는 HRmax 70%로 총 60분간 실시한 후 다음과 같은 결론을 얻었다. 첫째, 복싱에어로빅 운동프로그램 참여 결과 운동집단에서 체중, 체지방률과 근육량은 측정시기, 그룹과 측정시기의 상호작용이 유의한 차이를 나타냈으며(p<.001), 그룹별 측정시기 간의 대응표본 t-test 결과에서도 운동집단에서 유의한 수준의 감소 및 증가를 나타냈다(p<.001). 둘째, 복싱에어로빅 운동프로그램 참여 결과 운동집단에서 TC, TG, HDL-C, LDL-C 모두 그룹, 측정시기, 그룹과 측정시기의 상호작용효과도 유의한 차이를 나타냈으며(p<.01, p<.001), 그룹별 측정시 기간의 대응표본 t-test 결과 운동집단에서 유의한 감소와 증가를 나타냈다(p<.01). 셋째, 복싱에어로빅 운동프로그램 참여 결과 운동집단에서 오른손, 왼손, 오른발, 왼발의 혈관탄성은 그룹, 측정시기, 그룹과 측정시기의 상호작용 효과도 유의한 차이를 나타냈으며(p<.001), 그룹별 측정시기 간의 대응표본 t-test 결과 운동집단에서 유의한 증가를 나타냈다(p<.001). 이상의 결과를 종합해 볼 때, 12주간 복싱에어로빅 운동프로그램 참여는 신체조성 및 혈액성분을 개선시키고, 혈관순환 능력을 향상시켜 심혈관질환 등의 예방 및 개선 할 수 있을 것으로 사료된다. This study was conducted to test the effects of participation in 12-week program of boxing aerobics by obese middle-aged women on their body composition, blood constituents, and vascular compliance The samples are the middle-aged women in their forties or more, who has 30% or more body fat percentage, but has no medical history in cardiovascular disorders or metabolic diseases. The samples are divided into 8 of exercising group, and 8 of control group by random assignment. The intensity of boxing aerobics was HRmax 50% for the initial 4 weeks, HRmax 60% for the 5th to 8th week, and HRmax 70% for the 9th to 12th week. Each session took 60 minutes. The result is as follows. First, as a result of participating in the boxing aerobics program, body weight, body fat percentage, and muscle showed significant differences depending on the measuring period and the interacting term of the group and measuring period(p<.001), and the result of t-test on the sample matched to each group's measuring time also showed the significant increase or decrease in the exercising group(p<.001). Second, as a result of participating in the boxing aerobics program, the exercising group's TC, TG, HDL-C, and LDL-C, all showed significant differences in accordance with each group, measuring time, and the interaction term between groups and measuring time(p<.01, p<.001), and the result of t-test on each group's samples matched to the measuring time also shows significant increase or decrease in the exercising group(p<.01). Third, as a result of participating in the boxing aerobics programs, the vascular compliance of right hand, left hand, right hand, and left hand showed significant differences in accordance with each group, measuring time, and the interacting term between the measuring time and the group(p<.001), the t-test results of the samples matched to the each group's measuring time also showed significant differences in the exercising group(p<.001). To summarize the results above, it is suggested that the 12-week boxing aerobics program can improve body composition, blood constituents, and the blood circulation, which may prevent or enhance relevant diseases such as cardiovascular disorders.

FNDC5 and irisin in humans: I. Predictors of circulating concentrations in serum and plasma and II. mRNA expression and circulating concentrations in response to weight loss and exercise

ObjectiveIn mouse, PGC1-α overexpression in muscle stimulates an increase in expression of FNDC5, a membrane protein that is cleaved and secreted as a newly identified hormone, irisin. One prior study has shown that FNDC5 induces browning of subcutaneous fat in mice and mediates beneficial effects of exercise on metabolism, but a more recent study using gene expression arrays failed to detect a robust increase in FNDC5 mRNA in human muscles from exercising subjects. No prior study has reported on the physiological regulation and role of circulating irisin and FNDC5 in humans. Materials/MethodsA. FNDC5 gene expression studies: We first examined tissue distribution of FNDC5 in humans. B. Cross-sectional studies: Predictors of FNDC5 mRNA expression levels were examined in muscle tissues from 18 healthy subjects with a wide range of BMI. Assays were optimized to measure circulating FNDC5 and irisin levels, and their associations with anthropometric and metabolic parameters were analyzed in two cross-sectional studies that examined 117 middle-aged healthy women and 14 obese subjects, respectively. C. Interventional studies: The effect of weight loss on FNDC5 mRNA and/or circulating irisin levels was examined in 14 obese subjects before and after bariatric surgery. The effect of acute and chronic exercise was then assessed in 15 young healthy adults who performed intermittent sprint running sessions over an 8week period. ResultsTissue arrays demonstrated that in humans, the FNDC5 gene is predominantly expressed in muscle. Circulating irisin was detected in the serum or plasma of all subjects studied, whereas circulating FNDC5 was detected in only a distinct minority of the subjects. Cross-sectional studies revealed that circulating irisin levels were positively correlated with biceps circumference (used as a surrogate marker of muscle mass herein), BMI, glucose, ghrelin, and IGF-1. In contrast, irisin levels were negatively correlated with age, insulin, cholesterol, and adiponectin levels, indicating a possible compensatory role of irisin in metabolic regulation. Multivariate regression analysis revealed that biceps circumference was the strongest predictor of circulating irisin levels underlying the association between irisin and metabolic factors in humans at baseline. Both muscle FNDC5 mRNA levels and circulating irisin levels were significantly downregulated 6months after bariatric surgery. Circulating irisin levels were significantly upregulated 30min after acute exercise and were correlated mainly with ATP levels and secondarily with metabolites related to glycolysis and lipolysis in muscle. ConclusionsSimilar to mice, the FNDC5 gene is expressed in human muscle. Age and muscle mass are the primary predictors of circulating irisin, with young male athletes having several fold higher irisin levels than middle-aged obese women. Circulating irisin levels increase in response to acute exercise whereas muscle FNDC5 mRNA and circulating irisin levels decrease after surgically induced weight loss in parallel to decrease in body mass. Further studies are needed to study the regulation of irisin levels and its physiological effects in humans and to elucidate the mechanisms underlying these effects.

Reproductive characteristics and obesity in middle-aged women seen at an outpatient clinic in southern Brazil

The objective of this study was to investigate the association between reproductive events and abdominal obesity (waist circumference, ≥ 88 cm) and general obesity (body mass index, ≥ 30.0 kg/m) in a sample of women between the ages of 40 and 65 years treated at an outpatient clinic in southern Brazil. This was a cross-sectional study of a sample of 617 women from southern Brazil. Menopause status was classified as premenopausal, women who had regular menstrual cycles; perimenopausal, women who had irregular menstrual cycles whether in periodicity or flow; or postmenopausal, women whose last menstrual period occurred more than 12 months before the time of interview. Poisson regression was used to calculate crude and adjusted prevalence ratios and their respective 95% CIs. The prevalence rates of abdominal and general obesity were 66.6% (95% CI, 62.8%-70.3%) and 45.5% (95% CI, 41.5%-9.4%), respectively. After adjustment for demographic, socioeconomic, and behavioral variables, early menarche (≤ 11 y) and parity were strong predictors of abdominal and general obesity, presenting a dose-response relationship. Women with a history of three or more pregnancies and menarche at age 11 years or earlier had a 25% higher prevalence of abdominal obesity (95% CI, 1.07-1.46) and a 75% increase in obesity (95% CI, 1.37-2.24) compared with nulliparous or primiparous women with menarche at 14 years or older. Women with a postmenopause status showed an increase of 52% in general obesity, compared with those with a premenopause status. Characteristics of reproductive life may have a strong influence on body fat buildup in women during the menopausal transition.

PPAR-γ₂ 유전자의 Pro12Ala 다형성에 따른 복합운동 프로그램이 비만인 중년여성의 신체조성, 체력 및 혈중 생화학적 변인의 변화양상에 미치는 효과

The aim of this study was to investigate the effects of combined exercise program during weeks on the body composition, physical fitness and blood biochemical parameters according to the Pro12Ala polymorphism in the PPAR-γ2 gene in obese middle-aged women. A total of 34 participants were recruited in this study, and they performed combined exercise during weeks. Polymerase chain reaction(PCR)-and BstUI restriction fragment length polymorphism(RFLP) analysis was performed to analyze the Pro12Ala polymorphism in the PPAR-γ2 gene. Combined exercise program indicated the beneficial effects on the body composition, physical fitness and blood lipid profile and glucose metabolism of the subjects(p.05). The genotype distribution of the Pro12Ala polymorphism in the PPAR-γ2 gene were 85.3% for Pro12Pro genotype, and 14.7% for Pro12Ala genotype, respectively, and observed genotype frequencies were in Hardy-Weinberg equilibrium. However, this polymorphism was not significantly associated with any clinical parameters studied, and the significant differences between two genotypes were not observed in the changes of any metabolic parameters following combined exercise. Although, combined exercise program indicated the health-promoting effects on the mitigation of lifestyle-related disease such as obesity and non-insulin dependent diabetes mellitus(NIDDM) for the subjects, the Pro12Ala polymorphism in the PPAR-γ2 gene may not significantly contribute to the inter-individual differences on the clinical effects by combined exercise program. Further studies using larger smaple size and other candidate genes will be needed.

중년 비만여성들의 가압 트레이닝이 체성분, 호흡·순환계 기능 및 심혈관 반응에 미치는 효과

Pressurization walk training (PWT) with blood flow occlusion has been investigated with regard to muscle hypertrophy and physical fitness function in athletes and healthy people. However, the cardiorespiratory and cardiovascular responses of obese people to PWT are unknown. Thus, we investigated the effects of PWT on body composition (Weight, FM, LBM, %fat, BMI), cardiovascular responses (HR, SV, CO, TVC), and cardiorespiratory responses (VO2max, VEmax, HRmax) in middle-aged obese women. They participated in walk training with (n=15) blood flow occlusion and cross-sectional areas of the quadriceps on both legs. Five sets of 3-min walking (5.5 km/h at 5% grade) and 1-min resting were performed twice a day, 5 days/week for 3 weeks. The results showed that the LBM was significantly increased, and decreased body weight of reducing FM, %bodyfat in PWT (p<0.05). For the cardiovascular response, SBP and TPR were significantly decreased (p<0.05), and CO increased (p<0.05). In addition, the VO2max and VEmax were improved through PWT. Therefore, this study suggests that the presence of obesity in middle-aged women may result in body composition, cardiorespiratory, and cardiovascular responses caused by PWT.

Evaluation of vitamin B-12 level in middle-aged obese women with metabolic and non-metabolic syndrome: case-control study

To investigate the correlation between vitamin B12 and body mass index (BMI) along with insulin resistance (IR) in middle-aged obese women. Materials and methods: The study was designed as a case-control study. The study group included middle-aged obese women and the control group included aged-matched lean women. Weight, height, and hip and waist circumferences were measured. Biochemical parameters such as fasting and postprandial glucose, vitamin B12 and folic acid levels, and lipid profiles were assayed. Results: Enrolled in the study were 116 middle-aged obese and 103 aged-matched healthy lean women. The vitamin B12 level of the obese women was significantly lower than that of the lean women (244.1 ± 131.5 pg/mL vs. 336.2 ± 163.1 pg/mL, P = 0.002). However, there was no significant difference in folic acid levels between the groups (P > 0.05). The vitamin B12 level was similar in the obese women with metabolic syndrome and those without (245.1 ± 145.3 pg/mL vs. 241.2 ± 96.5 pg/mL, P > 0.05), but the level in the control group was significantly higher than that of patients with obesity and metabolic syndrome (P = 0.010 and P = 0.020, respectively). Vitamin B12 levels correlated with BMI (r = –0.259, P = 0.003) but not with IR (r = –0.053, P > 0.05). Conclusion: The vitamin B12 concentration was low in obese patients and this level negatively correlated with BMI, but not with homeostasis model assessment-estimated IR (HOMA-IR).

비만 중년여성들의 복합운동 프로그램이 비만관련인자에 미치는 영향

비만 중년여성들의 복합운동 프로그램이 비만관련인자에 미치는 영향

Effect of Massage with Warming Stone on Abdominal Obesity in Middle Aged Woman

Abdominal obesity, especially in middle-aged women, is closely associated with cardiovascular and metabolic disease. A lot of treatments including exercise and massage have been used to reduce abdominal obesity. Recently, massage with warming stone were frequently used for abdominal obesity in practice. However, there is no scientific evidence on the effect of massage with warming stone on abdominal obesity. Therefore, we investigated the effect of massage with warming stone on abdominal obesity in middle-aged women. Ten women (mean age 44.40±3.56 years, BMI 27.67±2.81 kg/m, WHR 0.92±0.04 ratio) without any health problem were recruited. All subjects were treated by massage with warming stone for 40 min once a day, twice a week, during 8 weeks. Data including height, weight, body mass index (BMI), % body fat (%BF), obesity index (OI), waist circumference (WC), waist to hip ratio (WHR), % abdominal fat (%AF), and thickness of abdominal subcutaneous fat (TAF) were measured at before treatment (PRE), 4 weeks (4 wks), and 8 weeks (8 wks) after treatment. Also, blood content such as total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDLC), and low-density lipoprotein cholesterol (LDL-C) were measured at PRE and 8 wks after treatment. The present results showed that most data such as weight, BMI, OI, WC1-3, WHR, %AF, and TAF were significantly decreased at 4 wks and 8 wks compared to the PRE (p⁄.05), while there were no statistical differences in %BF, TC, TG, HDL-C, and LDL-C between PRE and 8 wks. Related to the measurement site of WC, the biggest decrease of WC was observed in WC1 (4.7 cm) while the lowest decrease was observed in WC3 (2.74 cm). In summary, the findings of our study provide the evidence that massage with warming stone for 4 week reduced the risk of abdominal obesity in middle age woman by decreasing abdominal obese factors such as weight, BMI, OI, WC, WHR %AF, and TAF. Therefore, it can be suggested that massage with warming stone may be effective method for reducing abdominal obesity in middle age woman.

The effects of by the Type of Gene Mutation on ADR-β3 and PPAR-γ of aerobic exercise Intensity by obese middle-aged women on changes in Plasma LDH ․ CPK.

The effects of by the Type of Gene Mutation on ADR-β3 and PPAR-γ of aerobic exercise Intensity by obese middle-aged women on changes in Plasma LDH ․ CPK.

하타요가 운동이 비만중년여성의 신체조성, 혈청지질 및 건강체력에 미치는 영향

The purpose of this study was to analyze the effects of Hatha Yoga exercise on the body composition, serum lipids, and health-related fitness of obese middle-aged women. The subjects in the Hatha Yoga exercise group (n=9) were 18 obese middle-aged women that trained for 16 weeks and a control group (n=9). Body composition, serum lipids, and health-related fitness were measured in all of the subjects before the start of the training program and at the end of the 16 weeks. The findings of this study were as follows. Body weight, %BF, BMI, WHR, VFA, TC, TG, LDL-C, FFA, and HOMA-IR significantly decreased, whereas LBM, HDL-C, grip strength, back strength, push-ups, sit-ups, Harvard step test, and sitting trunk flexion significantly increased in the Hatha Yoga exercise group after 16 weeks. Therefore, regular and continuous Yoga exercise was effective in improving body composition, serum lipids, and health-related fitness. Consequently, Yoga exercise could be effective for preventing cardiovascular disease caused by obesity in middle-aged women.

Efficacy of Nordic Walking in Obesity Management

The effects of a Nordic walking (NW) program compared to those of a walking (W) program on physiological and perceptual variables in obese middle-aged women were investigated. Subjects (n=12 NW group, n=11 W group) trained over 12 weeks 3 times.week (-1). Body mass, body mass index (BMI), body fat, heart rate (HR), resting blood pressure, peak oxygen consumption (V˙O (2peak)) were measured before and after the training period. Moreover, HR, rating of perceived exertion (RPE) and adherence were recorded during all training sessions. After the training period body mass, body fat and diastolic blood pressure decreased in both groups (P<0.05) whereas V˙O (2peak) increased in the NW group (+3.7 ml.min (-1).kg (-1); P=0.005). During the training sessions, mean HR (P=0.021), HR at preferred walking speed (P=0.020) and % of time at high intensity (P=0.031) were higher in NW than in the W group. Finally, RPE was not influenced by the modality of exercise and NW group showed a higher rate of adherence (91±19% vs. 81±29%; P=0.011). To conclude, NW activity in obese women allows an increase in exercise intensity and adherence to a training program without increasing the perception of effort leading to enhanced aerobic capacity.

비만 중년여성의 12주간 운동프로그램 참여가 심박 변이도에 미치는 영향

Obesity is associated with an increased risk of cardiac complications that may be due to abnormal cardiovascular autonomic function reflected by reduced heart rate variability. We investigated the effect of a 12-wk exercise program on heart rate variability in middle-aged obese women. Ten middle-aged obese female volunteers with age 56.2±9.29y, % body fat 35.5±2.72% and BMI 27.1±2.8㎏/㎡. The training period was 12-wk, including 5~6 sessions/wk at an intensity of 40~70% of heart rate reserve(HRR), lasting for 60min/session. Measures of heart rate variability, obtained from both time-and frequency domain analysis of 5min ECG recording were as follows: mean RR interval and its standard deviation(SDNN), the mean square successive differences(rMMSSD), the low and high frequency components which were calculated as normalized units and their ratio(LF/HF). After the exercise program, body mass index and % body fat decreased to 4.8% and 5.5% respectively, which was accompanied by decrease in resting heart rate. Exercise training increased rMSSD by 54%, HFnu by 6.3% and decreased LFnu by 5.7%, LF/HF ratio by 12% significantly. The 12-wk exercise program led to changes in HRV indicative of an improvement in cardiac autonomic modulation in middle-aged women with obesity.

Health and Fitness Benefits of Whole-body Vibration Training (acceleration training) in Obese Middle-aged Women and Older Adults

Health and Fitness Benefits of Whole-body Vibration Training (acceleration training) in Obese Middle-aged Women and Older Adults

Reverse Osmosis Infrared Filtered Water Consumption Induces Weight Loss

Background: Previous research showed that weight loss in response to weight management program is influenced by total energy intake and water consumption. Whether or not purified water affects weight management is currently unknown. Methods: An intervention study of 29 middle-aged obese women who reported < 1L/day drinking water at baseline was carried out in Yaounde, Cameroon. Participants were randomly assigned to one of the two groups: (i) hypocaloric diet + physical activity + reverse osmosis infrared filtered water (ROIFW), and (ii) hypocaloric diet + physical activity. Weight, waist circumference and body fat were assessed at baseline, 4, 8, 12, 16, 20, 24, and 28 weeks. General Linear Model procedure of repeated measurements was used to determine whether weight loss as well as changes in waist circumference and body fat differ between the two study groups. Results: After 12 weeks from baseline, women in both groups lost an average of 7% of their initial body weight. A statistically significant difference in weight loss was observed between the ROIFW (7.9 kg; 95%CI: 6.5-9.3) and control (5.5 kg; 95%CI: 3.7-7.4; P=0.03) groups. No significant difference was apparent in both waist circumference and body fat throughout the intervention although women in the ROIFW group experienced higher reduction. Conclusion: Our results suggest that obese women using ROIFW may augment weight loss when combined with hypocaloric diet and physical activity. More extensive data are warranted to confirm these findings, as well as to address issues of optimal volume and timing of ROIFW consumption.