D. Trump's republican administration has substantially modified US strategic estimation of security challenges and threats, facing the country. The "National Security Strategy – 2017" became a fundamental basis of the security policy. The authors of the "Strategy…" believed Russia and China to be the main security policy problems, threatening the world status of the U.S.A. and a challenge for it's interests. The answer to the challenges should include deployment of the ABM system, capable of neutralizing threats, created by N.Korea and Iran. Opposing China and Russia, called "revisionist states", seeking to change the international status-quo, requires building up and modernizing arms and Armed Forces, in particular, security predominance in nuclear forces, space and cyber-space. An active role was designed for diplomacy and reconnaissance community, involving an increase of their efficiency. On the regional level, priorities included Indo-Pacific region, where the United States had to contain Chinese expansion, and Europe, where Washington intended to counter Russian subversive activity and aggression and to support NATO's defense efforts. Nuclear Posture Review (2018) was one of the key foreign policy strategic documents for the administration of 45th US President Donald Trump. In the context of increasing political and economic confrontation with the People's Republic of China and the aggravation of relations with Iran and North Korea, which were caused by the nuclear component itself, this strategy returned to the methods of confrontation and the nuclear deterrence of the Cold War era. It emphasized the complementarity of the power potential of the armed forces and the diplomatic levers of the international struggle. In the period of new aggravation in the international system caused by the full-scale invasion of the Russian Federation into Ukraine, these very components of the doctrine can become prognostically effective for the current and future American administrations. This article is designed to analyze the key aspects of the National Security Strategy-2017 and the 2018 Nuclear Posture Review that relate to foreign policy and highlight the special aspects and tools that are still relevant for application by the current administration of Joseph Biden in the crisis of the international system.