The stabilization issue for a nonlinear piezoelectric beam system with variable coefficients and time-varying delay in the control input is considered. The system is constituted by two strongly coupled nonlinear hyperbolic equations, in one of which a kind of distributed control is actuated and time-varying delay exists in the control input. The feedback gains are also time-varying ones. We first apply Kato's variable norm technique to show the well-posedness of the system without nonlinear terms and based on which, the well-posedness of the whole nonlinear system is proved by the fixed-point theory. The exponential stability of the nonlinear time-delay coupled PDEs' system is further proved by the energy estimates together with multiplier techniques under certain conditions. The stability of its corresponding electrostatic/quasi-static model is also investigated. Finally, some numerical simulations are given to illuminate the results obtained in this work.