This study investigated how walking in occupational footwear (OF) affects slip outcome and slip recovery strategies in response to an unexpected slip. Participants walked along a walkway while either barefoot (BF; n = 13) or in OF (n = 12). The first five walking trials consisted of the no-slip condition, where a high friction sheet was placed halfway down the walkway to ensure a low probability of a slip. Prior to the sixth walking trial and without the participant’s knowledge, the sheet was replaced with a low friction surface to induce an unexpected slip. Results obtained during the no-slip trials indicated that compared to the BF group, the OF group walked with a 15% smaller required coefficient of friction (p = 0.04), a 12° greater dorsiflexion at heel strike (p = 0.007) and a 7° more extended knee position at 100 ms following heel strike (p = 0.008). The OF group also demonstrated greater electromyographic (EMG) activity in the hamstrings of the stance limb and the gastrocnemius of the contralateral limb prior to and after heel strike. When the low friction surface was unexpectedly encountered, a slip was induced in both groups. But compared to the BF group, the OF group experienced a less severe slip, with the slip being 42% shorter (p = 0.004) and 75% slower (p < 0.001), and exhibited a 19–71% lesser EMG activation when responding to the slip. Although these results provide initial evidence for the benefits of wearing OF to minimise the consequence of a slip in the workplace, further research is needed to determine whether the altered walking patterns associated with wearing OF (e.g., greater dorsiflexion, reduced knee range of motion, etc.) may have contributed to the decrease in slip severity.