Metal Nanoparticles Research Articles

Hierarchical exsolution in vertically aligned heterostructures

Metal nanoparticle exsolution from metal oxide hosts has recently garnered great attention to improve the performance of energy conversion and storage devices. In this study, the nickel exsolution mechanisms in a vertically aligned nanostructure (VAN) thin film of heteroepitaxial (Sr0.9Pr0.1)0.9Ti0.9Ni0.1O3−δ-Ce0.9Gd0.1O1.95 with a columnar architecture was investigated for the first time. Experimental results and Density Functional Theory (DFT) calculations reveal that the multiple vertical interphases in a VAN with a hierarchical arrangement provide faster and more selective Ni diffusion pathways to the surface than traditional bulk diffusion in epitaxial films. Kinetic studies conducted at different temperatures and times indicate that the nucleation process of the exsolved metal nanoparticles primarily takes place at the surface through the phase boundaries of the columns. The vertical strain is crucial in preserving the film’s microstructure, yielding a robust heteroepitaxial architecture after reduction. This innovative heteromaterial opens up new possibilities for designing efficient devices through advanced structural engineering to achieve controlled nanoparticle formation.

Regulating the location relationship between Cu nanoparticles and Pt atoms to enhance the catalytic hydroisomerization performance: Together or apart?

Single atom catalysts have been recently reported as the efficient catalysts for hydroisomerization compared to the conventional nanoparticle catalyst. Despite the fascinating advantage in enhancing the metal activity or reducing the catalyst cost, the long-term stability of the single atom catalyst seemed not that satisfactory, especially when reacting under atmospheric pressure. Herein, Pt single atom catalysts were combined with Cu nanoparticles by different means to explore a new way to improve the catalytic performance. Cu nanoparticles were located away from Pt sites to form a binary catalyst, or acted as the support of Pt atoms to form a single atom alloy (SAA) catalyst. With the binary catalyst Pt1–0.1Cu@CS, the conversion of the n-heptane after time on stream of 50 h increased to 70.3 %, higher than Pt1@CS (47.3 %). Besides, excessive Cu nanoparticles in the binary catalyst were found rather harmful to the catalysis instead. However, the SAA catalyst Pt1Cu@SAPO-11 showed a poor activity in hydroisomerization compared to Pt1@CS, indicating that the alloy structure should go against the activation of reactant. The roles of Pt atoms and Cu nanoparticles in different catalysts were discussed in detail. The reaction mechanism of hydroisomerization was refined with the different functions of the dual metal sites. This work might be instructive for the design of single atom catalysts combined with metal nanoparticles.

Nitrogen-doped carbon nanosheet confined PtNi alloy for efficient acidic electrocatalytic hydrogen evolution reaction

Low intrinsic electrocatalytic activity and inferior conductivity limit the application of Ni/NC in acidic electrocatalytic hydrogen evolution reaction (HER). Herein, we prepared nitrogen-doped carbon nanosheet confined PtNi alloy electrocatalysts (PtNi/NC-10) using PtCl62− electrostatic adsorption coupling melamine pyrolysis nitriding strategy. PtNi alloying was confirmed by the crystallinity decrease and lattice expansion of Ni/NC. The alloying and confinement effect of Metal-Organic Frameworks (MOFs) suppresses the oxidation and agglomeration of metal nanoparticles during pyrolysis, thus significantly reducing particle size, increasing specific surface area, and promoting the exposure of active sites. The strong electronic interaction between Pt and Ni optimizeds the surface charge distribution, enhancing the adsorption of H species on electron-rich Pt sites, thereby improving reaction kinetics. In addition, PtNi alloying improves the conductivity of the material, accelerating charge transfer and proton transport. Consequently, the prepared PtNi/NC-10 exhibits superior HER performance than Ni/NC in 0.5 M H2SO4 solution, even comparable to commercial 20 wt% Pt/C, with the overpotentials of 35 mV at 0.01 A cm−2. Furthermore, the electrocatalysts assembled PtNi/NC-10-CP‖RuO2-TFF proton exchange membrane (PEM) electrolyzer only requires 2.32 V cell voltage to achieve 1 A cm−2, presenting practical application prospects. Our work provides a novel idea for designing efficient and stable MOFs confined to alloy-based HER electrocatalysts.

Plasmonic Nanocubes with a Controllable "Crescent Arc" Facet: Tunable Hotspot Engineering for Highly Reliable and Sensitive SERS Detection.

The fine control of the nanogap and morphology of metal nanoparticles (NPs) has always been an obstacle, hindering the development and application of surface-enhanced Raman scattering (SERS) quantitative detection. Here, Au/4-mercaptobenzoic acid@Ag@Au-Ag bimetal core-shell nanocubes (NCs) with a "crescent arc" facet (C-Au/4MBA@Ag NCs) as a highly reliable and sensitive surface-enhanced Raman scattering SERS substrate is proposed for the first time. The bifunctional internal standard (IS) molecules (4MBA) govern the morphology of metal shells to maintain cubic configuration and provide calibration for SERS signals' flotation. In parallel, the controllable curvature of the C-Au/4MBA@Ag NCs is directly modulated by adjusting the relative rates of the galvanic replacement and co-reduction reaction, which generates a controllable interparticle nanogap to offer large depositing spaces for analytes and improve authoritative SERS signals' enhancement. The proposed C-Au/4MBA@Ag NCs exhibit an enhancement factor of up to 4.8 × 1010 and contribute to the ultralow RSD (7.9%). These C-Au/4MBA@Ag NCs also enable the detection of hazardous pesticide residues such as methamidophos and thiram in herbal plants with a complex matrix, with an average detection accuracy of up to 96%. In summary, this study achieves a fine control strategy of the "crescent arc" surface for improving SERS performance and explores the practical application potential for accurate and sensitive Raman detection of hazardous substances.

Highly-dispersed CdS nanoparticles coating hierarchical Ni@NC derived from ultrathin nanosheets NMOF-Ni: Photocatalytic hydrogen evolution coupled with alcohol oxidation

Photocatalytic water-splitting into H2 in conventional procedures often requires sacrificial agents to consume unutilized holes to boost the reaction. Herein, we cast off the dependence on the addition of sacrificial agents and develop a dual-functional photocatalyst CdS/Ni@NC for coupling H2 evolution with value-added benzyl alcohol (BA) oxidation in anaerobic aqueous solution, wherein CdS/Ni@NC was synthesized by in-situ anchoring of CdS nanoparticles (NPs) onto NMOF-Ni ultrathin nanosheets-derived nitrogen-doped wrinkled graphitic carbon layers encapsulated metallic Ni NPs (Ni@NC). The optimized photocatalyst CdS/Ni@NC(5) achieves a high visible-light-driven H2 evolution rate of 1881 μmol·g−1·h−1 and a benzaldehyde (BAD) yield of 3254.2 μmol·g−1·h−1, with nearly 100 % selectivity over a 6 h period, which are 32.6 and 10.5 folds of that for CdS alone, respectively. Further in-depth experimental characterizations reveal that the hierarchical Ni@NC serves as an ideal support to enable high dispersion of CdS NPs, thus improving light absorption and facilitating full contact with reactants. Besides, the widely distributed Ni NPs, effectively shielded by nitrogen-doped wrinkled graphitic carbon layers, can not only promote photogenerated charge transfer for enhanced H2 production but also facilitate the cleavage of the Cα–H bond in BA, contributing to achieving high aldehyde selectivity. This study, integrating carbonized ultrathin nanosheets NMOF-Ni with CdS to synergistically enhance surface redox reactions, holds significant promise for advancing the development of high-performance photocatalysts for integrated production of solar hydrogen and value-added solar chemicals.

Bismuth Nanoparticles and Single Iron Atoms on Carbon Derived from a Covalent Organic Framework Synergistically Catalyze the Oxygen Reduction Reaction.

The utilization of catalysts comprising metal nanoparticle has been beneficial for enhancing the performance of oxygen reduction reaction (ORR). However, the inadequate intrinsic activity of these catalysts still presents a significant challenge, limiting their overall effectiveness. This issue can be addressed by introducing single atoms, which can create a synergistic effect with the nanoparticles to catalyse and thereby improve performance. Nevertheless, the synergistic catalysis of nanoparticles and single atoms is still under investigation. In this study, we fabricated a core-shell structured carbon framework incorporating Fe single atoms and Bi nanoparticles through the pyrolysis of COF and MOF core-shell structures. Introducing Fe single atoms into ZIF-8, with Fe-ZIF-8 as the core and Bi-containing COF as the shell, resulted in higher ORR activity. The catalyst exhibited a half-wave potential of 0.867 V and a high current density of 6.68 mA cm-2 in 0.1 M KOH, which were comparable to those of Pt/C equivalent. This study provides new research concepts for exploring the application of single atoms and nanoparticles in catalytic oxygen reduction reactions through synergistic effects.

Highly efficient dip catalysts using bacterial cellulose impregnated with self-crosslinked glycol chitosan and silver nanoparticles for 4-nitrophenol reduction

The application of environmentally friendly and sustainable catalysts requires efficient and safe preparation methods using cheap and renewable materials. Although many metal nanoparticles (NPs) have low colloidal stability, they are still very effective as catalysts. Using a straightforward method, we developed a bacterial cellulose–glycol chitosan–silver (BC–GCS–Ag) nanocomposite, by introducing both AgNPs and self-crosslinked GCS within the BC network. Self-crosslinking of GCS occurred during the formation of AgNPs by employing the glycol moieties for reduction to produce aldehyde functionalities, thereby forming Schiff's base bonds within the GCS structure. Using GCS, well-defined AgNPs within the BC matrix. The formation of AgNPs and the self-crosslinking of GCS were characterized using UV–visible spectroscopy, Fourier transform infrared (FTIR) spectroscopy, X-ray diffraction (XRD), scanning electron microscopy (SEM), and transmission electron microscopy (TEM). The results showed that spherical AgNPs with a mean diameter of 10 nm exhibited a well-organized structure within the BC–GCS matrix. The BC–GCS–Ag nanocomposite was applied as dip catalyst for the reduction of 4-nitrophenol (4NP) to 4-aminophenol (4AP), chosen as a model reaction. The results showed that the catalytic reaction was completed within 4 min, with high reusability (10 times) and without loss of catalyst. The reaction followed pseudo-first-order kinetics with a high rate constant of 0.582 min−1. Therefore, the BC–GCS–Ag dip catalyst is an attractive alternative for environmentally friendly and sustainable catalysis, owing to its exceptional catalytic performance, high recyclability, and stability, as well as the minimal environmental footprint of the supporting materials.

Research on Efficient Electromagnetic Shielding Performance and Modulation Mechanism of Aero/Organo/Hydrogels with Gravity-Induced Asymmetric Gradient Structure.

To eliminate electromagnetic pollution, it is a challenging task to develop highly efficient electromagnetic shielding materials that integrate microwave absorption (MA) performance with high shielding capability and achieve tunability in shielding performance. Asymmetrically structured aero/organo/hydrogels with a progressively changing concentration gradient of liquid metal nanoparticles (LMNPs), induced by gravity, are prepared by integrating the conductive fillers Ti3C2Tx MXene and LMNPs into a dual-network structure composed of polyvinyl alcohol and cellulose nanofibers. Benefiting from the unique structure, which facilitates the absorption-reflection-reabsorption process of electromagnetic waves along with conductive fillers and the porous structure, three types of gels demonstrate efficient shielding performance. HPCML achieves a total shielding effectiveness (SET) of up to 86.9dB and a reflection shielding effectiveness (SER) of as low as 2.85dB. Especially, APCML, with an ultra-low reflection coefficient (R) of 6.4%, achieves compatibility between shielding performance and MA properties. The relationship between dispersing media (air, water, and glycerol/water) and the shielding performance of aero/organo/hydrogels is explored, thereby achieving modulation of the shielding performance of the gel system. The work has paved a clear path for integrating absorption and shielding capabilities into a composite material, thereby providing a prototype of a highly efficient shielding material with MA performance.

Anticancer Efficacy of Biosynthesized Zinc Oxide and Gold Nanoparticles

Abstract Introduction/Objective Introduction: Advancements in nanoscale materials have led to the exploration of metal oxides for cancer diagnosis and therapy. Zinc oxide nanoparticles (ZnO NPs) and gold nanoparticles (Au NPs) are particularly promising due to their biocompatibility and anticancer properties demonstrated across various cancer cell lines. Objectives This study aimed to isolate fungal endophytes from Eucalyptus sideroxylon leaves and utilize them for the biosynthesis of nanoparticles (ZnO NPs and Au NPs) to assess their anticancer activity. Methods/Case Report Methods: Healthy Eucalyptus sideroxylon samples were collected from a desert research center, and endophytes were isolated and cultivated. The fungal biomass was processed to synthesize ZnO NPs and Au NPs. Cell lines were propagated for cytotoxicity experiments using the MTT assay in a 96-well plate format. Results (if a Case Study enter NA) Results: Biosynthesized ZnO and Au NPs exhibited anticancer activity against HCT-116 and CACO2 cell lines. The IC50 values for ZnO NPs were 5.06 μg/mL for HCT-116 and 6.07 μg/mL for CACO2, while Au NPs showed IC50 values of 5.9 μg/mL for HCT-116 and 1.1 μg/mL for CACO2. ZnO NPs demonstrated dose-dependent toxicity on HCT-116 cells, with increasing concentrations leading to a reduction in cell viability. Similarly, Au NPs exhibited dose-dependent cytotoxicity on both cell lines. Conclusion Conclusion: This study underscores the potential of endophytic fungi for biosynthesizing metal nanoparticles with significant anticancer effects. ZnO NPs displayed superior efficacy against colon cancer cells compared to Au NPs, indicating their potential as therapeutic agents. The findings highlight the importance of exploring natural sources for nanoparticle synthesis and their application in cancer therapy.

Multifunctional gold nanoparticles for cancer theranostics.

The diagnosis and treatment of cancer can often be challenging requiring more attractive options. Some types of cancers are more aggressive than others and symptoms for many cancers are subtle, especially in the early stages. Nanotechnology provides high sensitivity, specificity and multimodal capability for cancer detection, treatment and monitoring. In particular, metal nanoparticles (NPs) such as gold nanoparticles (AuNPs) are attractive nanosystems for researchers interested in bioimaging and therapy. The size, shape and surface of AuNPs can be modified for improving targeting and accumulation in cancer cells, for example through introduction of ligands and surface charge. The interactions of AuNPs with electromagnetic radiation (e.g., visible-near-infrared, X-rays) can be used for photothermal therapy and radiation therapy, through heat generated from light absorption and emission of Auger electrons, respectively. The subsequent expansion and high X-ray attenuation from AuNPs can be used for enhancing contrast for tumor detection (e.g., using photoacoustic, computed tomography imaging). Multi-functionality can be further extended through covalent/non-covalent functionalization, for loading additional imaging/therapeutic molecules for combination therapy and multimodal imaging. In order to cover the important aspects for designing and using AuNPs for cancer theranostics, this review focuses on the synthesis, functionalization and characterization methods that are important for AuNPs, and presents their unique properties and different applications in cancer theranostics.

Introduction and Development of Surface-Enhanced Raman Scattering (SERS) Substrates: A Review.

Since its discovery, the phenomenon of Surface Enhanced Raman Scattering (SERS) has gradually become an important tool for analyzing the composition and structure of substances. As a trace technique that can efficiently and nondestructively detect single molecules, the application of SERS has expanded from environmental and materials science to biomedical fields. In the past decade or so, the explosive development of nanotechnology and nanomaterials has further boosted the research of SERS technology, as nanomaterial-based SERS substrates have shown good signal enhancement properties. So far, it is widely recognized that the morphology, size, composition, and stacking mode of nanomaterials have a very great influence on the strength of the substrate SERS effect. Herein, an overview of methods for the preparation of surface-enhanced Raman scattering (SERS) substrates is provided. Specifically, this review describes a variety of common SERS substrate preparation methods and explores the potential and promise of these methods for applications in chemical analysis and biomedical fields. By detailing the influence of different nanomaterials (e.g., metallic nanoparticles, nanowires, and nanostars) and their structural features on the SERS effect, this article aims to provide a comprehensive understanding of SERS substrate preparation techniques.

Protein Cage Directed Assembly of Binary Nanoparticle Superlattices.

Inorganic nanoparticles can be assembled into superlattices with unique optical and magnetic properties arising from collective behavior. Protein cages can be utilized to guide this assembly by encapsulating nanoparticles and promoting their assembly into ordered structures. However, creating ordered multi-component structures with different protein cage types and sizes remains a challenge. Here, the co-crystallization of two different protein cages (cowpea chlorotic mottle virus and ferritin) characterized by opposing surface charges and unequal diameter is shown. Precise tuning of the electrostatic attraction between the cages enabled the preparation of binary crystals with dimensions up to several tens of micrometers. Additionally, binary metal nanoparticle superlattices are achieved by loading gold and iron oxide nanoparticles inside the cavities of the protein cages. The resulting structure adopts an AB2 FCC configuration that also impacts the dipolar coupling between the particles and hence the optical properties of the crystals, providing key insight for the future preparation of plasmonic and magnetic nanoparticle metamaterials.

Synthesis of metal nanoparticles on graphene oxide and antibacterial properties.

Pathogen-induced infections and the rise of antibiotic-resistant bacteria, such as Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus), pose significant global health challenges, emphasizing the need for new antimicrobial strategies. In this study, we synthesized graphene oxide (GO)-based composites functionalized with silver nanoparticles (AgNPs) and copper nanoparticles (CuNPs) as potential alternatives to traditional antibiotics. The objective is to assess the antibacterial properties of these composites and explore their efficacy against E. coli and S. aureus, two common bacterial pathogens. The composites are prepared using eco-friendly and conventional methods to ensure effective nanoparticle attachment to the GO surface. Structural and morphological characteristics are confirmed through SEM, AFM, EDS, XRD, UV-vis, FTIR, and Raman spectroscopy. The antibacterial efficacy of the composites is tested through disk diffusion assays, colony-forming unit (CFU) counts, and turbidimetry analysis, with an emphasis on understanding the effects of different nanoparticle concentrations. The results demonstrated a dose-dependent antibacterial effect, with GO/AgNP-1 showing superior antibacterial activity over GO/AgNP-2, particularly at lower concentrations (32.0μg/mL and 62.5μg/mL). The GO/CuNP composite also exhibited significant antibacterial properties, with optimal performance at 62.5μg/mL for both bacterial strains. Turbidimetry analysis confirmed the inhibition of bacterial growth, especially at moderate concentrations, although slight nanoparticle aggregation at higher doses reduced efficacy. Lastly, both GO/AgNP and GO/CuNP composites demonstrated significant antibacterial potential. The results emphasize the need to fine-tune nanoparticle concentration and refine synthesis techniques to improve their efficacy, positioning these composites as strong contenders for antimicrobial use.

Using In situ Transmission Electron Microscopy to Study Strong Metal-Support Interactions in Heterogeneous Catalysis.

Precisely controlling the microstructure of supported metal catalysts and regulating metal-support interactions at the atomic level are essential for achieving highly efficient heterogeneous catalysts. Strong metal-support interaction (SMSI) not only stabilizes metal nanoparticles and improves their resistance to sintering but also modulates the electrical interaction between metal species and the support, optimizing the catalytic activity and selectivity. Therefore, understating the formation mechanism of SMSI and its dynamic evolution during the chemical reaction at the atomic scale is crucial for guiding the structural design and performance optimization of supported metal catalysts. Recent advancements in in situ transmission electron microscopy (TEM) have shed new light on these complex phenomena, providing deeper insights into the SMSI dynamics. Here, the research progress of in situ TEM investigation on SMSI in heterogeneous catalysis is systematically reviewed, focusing on the formation dynamics, structural evolution during the catalytic reactions, and regulation methods of SMSI. The significant advantages of in situ TEM technologies for SMSI research are also highlighted. Moreover, the challenges and probable development paths of in situ TEM studies on the SMSI are also provided.

Highly Dispersed Pd@ZIF‐8 for Photo‐Assisted Cross‐Couplings and CO2 to Methanol: Activity and Selectivity Insights

AbstractOur study unveils a pioneering methodology that effectively distributes Pd species within a zeolitic imidazolate framework‐8 (ZIF‐8). We demonstrate that Pd can be encapsulated within ZIF‐8 as atomically dispersed Pd species that function as an excited‐state transition metal catalyst for promoting carbon–carbon (C−C) cross‐couplings at room temperature using visible light as the driving force. Furthermore, the same material can be reduced at 250 °C, forming Pd metal nanoparticles encapsulated in ZIF‐8. This catalyst shows high rates and selectivity for carbon dioxide hydrogenation to methanol under industrially relevant conditions (250 °C, 50 bar): 7.46 molmethanol molmetal−1 h−1 and >99 %. Our results demonstrate the correlations of the catalyst structure with the performances at experimental and theoretical levels.

How natural products involved in the ‘green’ synthesis of metallic nanoparticle?

How natural products involved in the ‘green’ synthesis of metallic nanoparticle?

Antibacterial Capabilities of Metallic Nanoparticles and Influencing Factors

ABSTRACTThe increase of antibiotic resistance in bacteria has become a major concern for successful diagnosis and treatment of infectious diseases. Over the past few decades, significant progress has been achieved on the development of nanotechnology‐based medicines for combating multidrug resistance in microorganisms. Among these, metallic nanoparticles (MNPs) hold great promise in addressing this challenge due to their broad‐spectrum and robust antimicrobial properties. This review illustrates the antibacterial activities of MNPs and further elucidates how different factors including synthesis method, size, shape, surface charge, pH, dose, type of capping or stabilizing agents of MNPs, and Gram‐type of the bacteria, impact their antibacterial activities, which are expected to promote the future development of more potent MNP‐based antibacterial agents.

A Novel Super-Toughness and Self-Healing Solid Polymer Electrolyte for Solid Sodium Metal Batteries.

Solid sodium metal batteries (SSMBs) offer an alternative promising power source for electrochemical energy storage due to their high energy density and high safety. However, the inherent sodium dendrite growth and poor mechanical properties of electrolytes seriously limit their application. Herein, a network structure composed of polyethylene oxide-based composite polymer electrolyte (CPE) is designed with liquid metal nanoparticles (LM) for SSMBs, in which LM can move in the solid electrolyte with the electric field driven. This effect can facilitate the inactivated sodium return to the metal sodium anode, and alloy with dendrites at the same time, which is beneficial for inhibiting the growth of dendrites. The symmetric cell with the CPE containing LM achieves good cyclic stability of more than 1800 and 800h at 0.1 and 0.2mAcm-2, respectively. The energy density of the pouch battery can reach 230Whkg-1. In sum, LM presents great potential to be employed as a performance reinforcement filler for CPEs, which paves the way for achieving high-performance SSMBs.

Enhancing Sensitivity and Selectivity: Current Trends in Electrochemical Immunosensors for Organophosphate Analysis.

This review examines recent advancements in electrochemical immunosensors for the detection of organophosphate pesticides, focusing on strategies to enhance sensitivity and selectivity. The widespread use of these pesticides has necessitated the development of rapid, accurate, and field-deployable detection methods. We discuss the fundamental principles of electrochemical immunosensors and explore innovative approaches to improve their performance. These include the utilization of nanomaterials such as metal nanoparticles, carbon nanotubes, and graphene for signal amplification; enzyme-based amplification strategies; and the design of three-dimensional electrode architectures. The integration of these sensors into microfluidic and lab-on-a-chip devices has enabled miniaturization and automation, while screen-printed and disposable electrodes have facilitated on-site testing. We analyze the challenges faced in real sample analysis, including matrix effects and the stability of biological recognition elements. Emerging trends such as the application of artificial intelligence for data interpretation and the development of aptamer-based sensors are highlighted. The review also considers the potential for commercialization and the hurdles that must be overcome for widespread adoption. Future research directions are identified, including the development of multi-analyte detection platforms and the integration of sensors with emerging technologies like the Internet of Things. This comprehensive overview provides insights into the current state of the field and outlines promising avenues for future development in organophosphate pesticide detection.

One-pot synthesis of monodisperse silver-lignin particles: Enhanced antibacterial agents against antibiotic-resistant bacteria

Lignin-based supports for metal nanoparticles (NPs) have attracted significant attention due to their abundant functional groups that facilitate NPs loading. However, many studies involve a two-step process: fabricating lignin particles and then reducing metal ions to NPs using physical energy consumption or chemical reduction. A one-step in-situ reduction method for NP synthesis on carrier surfaces, eliminating energy consumption, is needed for environmentally friendly and sustainable approach. Herein, we demonstrate that poly-l-lysine (PL) controls the self-assembly kinetics of kraft lignin (KL), and reduces silver ion (Ag+) to silver nanoparticles (AgNPs), forming highly monodisperse, co-self-assembled PL-KL particles (Ag@PL-KLPs) without chemical reducing agents or energy consumption. PL facilitated rapid KL desolvation, promoting intermolecular interactions and silver ion adsorption, followed by an efficient, separate nucleation and growth process yielded Ag@PL-KLPs approximately 270 nm in size with a narrow distribution. Notably, Ag@PL-KLPs exhibited enhanced bacteriostatic and bactericidal properties against antibiotic-resistant bacteria (ARB), including both Gram-negative and Gram-positive strains, at concentrations of 250 μg/mL. Leveraging biomass-derived lignin and this cost-effective, one-step green synthesis approach offers a sustainable method for avoiding antibiotic overuse and environmental contamination.