Abstract Background Sedentary behavior and physical inactivity are associated with an increased risk of chronic disease and mortality. Studies have shown the benefits of active transport to reduce NCDs. In Colombia, studies have been developed to determine the factors associated with the use of active transport, in cities such as Bogota but not nationally, therefore, this study seeks to determine the factors associated with the use of active transport in users of the National Program of Habits and Healthy Lifestyle (HEVS) led by the Ministry of Sport of Colombia in partnership with municipal sports and departmental. Methods The research presented a quantitative approach on a retrospective basis. The population consisted of 75,086 users of the HEVS program in 2019, over 18 years old (average = 44.04 and D.E. = 15.75 years old) of which 87.7% were women. For the statistical analysis a forward logistic regression model was carried out, with the dependent variable: active transport use (0 = no active transport use and 1 = active transport use). Results 41.6% of 75086 participants reported using active transport, corresponding to 31,211. Regular users, who attend physical activity programs 3 times a week, report a higher probability of using active transport OR = 1.38 (95% CI 1.31 to 1.45), compared to those who attend less than 3 times a week. Being female represents a greater probability of using active transport compared to men, OR = 1.39 (95% CI 1.32 to 1.47), those who add salt to food are also more likely to use active transport than those who do not add, OR = 2.04 (95% CI 1.92 to 2.26) and in terms of physical activity, those who meet the minimum recommendations in minutes a week use active transport more likely than those who do not comply, OR = 1.49 (95% CI 1.4 to 1.6). Conclusions Using active transport is associated with greater compliance with weekly physical activity recommendations. Women are more likely to use active transport just like people who add salt to food. Key messages • In order to reduce NCDs in the Colombian population, walking or cycling is proposed because it is associated with a greater probability of compliance with weekly physical activity recommendations. • Formulating public policies in Colombia that encourage the use of active transport would contribute to meeting weekly physical activity requirements.