Zinc-Cerium-Ferrite Zn2+ xFe2+ 1-xCe3+ yFe3+ 2-yO4@Graphene oxide@Titania nano-composite prepared at different ratios exhibit many better properties and improve their structural properties. The Nano-particles of ferrite Zn2+ xFe2+ 1- xCe3+ yFe3+ 2-yO4 Spinal (0≤ x & y ≥ 2) (x=0,0.2,0.4,0.6,0.8,1 and y=1,0.8,0.6,0.4,0.2,0) powder were synthesized by substitution of A- and B- sites in a sol-gel method the multi-metallic complex precursor route using citrate. The obtained powders calcinated at 800 ºC for 4 hours. The Modified Hummer process was used to create the Graphene oxide layer by solvothermal hydrolysis and powders obtained on calcinations at 600 º c for 2 hours. Again, the second coating of Titania was prepared by the solvothermal method of the obtained powders calcinated at 600 ºC for 2 hours. The result shows Zinc-Cerium-Ferrite@Grapheneoxide@Titania on various ratios to obtain microstructure, crystallite sizes obtained in the range of 25-52 nm, and good cyclic voltammeter stability 250 cycles, antibacterial, Antifungal, and Antioxidant activity.