The article provides a comprehensive assessment of the psychophysiological factors affecting the professional adaptation of cadets. It emphasizes that professional development entails the formation of professional orientation, competence, socially significant and professionally important qualities, their integration, readiness for continuous professional growth, and the search for optimal methods to perform activities of high quality and creativity in accordance with individual psychological characteristics. Various approaches to specialist development have been examined by researchers and practitioners, including professional self-determination, stages of specialization, development of professionally important qualities, motivation in work activities, and the fundamentals of labor activity. The main theories that unify these approaches are the theory of types of professional life (structural concepts), motivational theories, and theories of individuality. The study highlights that the adaptation process is influenced by personal factors such as stress resistance, personality type, and emotional perception. The research utilized data obtained through a rhythmograph system, which monitors ECG signals and heart rate variability in the first standard lead, allowing for statistical time and spectral analysis of heart rate. In the initial stage, the assessment of nonverbal and general intelligence development levels was analyzed using the "Color Progressive Matrices" test by J. C. Raven. In the subsequent stage, the correlation between intelligence level and LF norm, HF norm, and LnLF/HF under load was determined. Finally, the adaptability level of the respondents to modern functioning conditions was assessed using the multi-level personality questionnaire "Adaptability" by A. Maklakov and S. Chermianin. The obtained data indicate an inverse proportional relationship between these indicators: "high stress - low adaptability" and vice versa. The article also highlights the significance of nervous-psychic tension, in addition to stress, as an unfavorable factor affecting performance. It lists the main causes contributing to the development of nervous-psychic tension. Furthermore, the works of M. Agadzhanyan, V. Kaznacheev, and S. Kaznacheev identify three qualitatively different types of adaptive human response: "sprinter," "stayer," and "intermediate" types (based on the criterion of time to perform submaximal work). To enhance adaptive abilities, the article proposes the utilization of the bioactivation optimization technique, which effectively enhances a person's psychophysiological functions and meets the requirements for psychophysiological support in military professional activities.