Morphological Variants Research Articles

Association of Ki-67 expression in radical cystectomy specimens of infiltrating urothelial carcinoma with histopathological parameters

Urothelial carcinoma is the most common neoplasm of urinary bladder. Antigen Ki-67 is a nuclear protein that is necessary for cellular proliferation. The aim of this study was to determine the association of expression of Ki-67 with histopathological parameters in radical cystectomy specimens of histologically diagnosed cases of infiltrating urothelial carcinoma. This is a cross-sectional study conducted among 36 cases of infiltrating urothelial carcinoma collected from Department of Pathology, Bangabandhu Sheikh Mujib Medical University. Histopathological parameters i.e. morphologic variants, stage (pT), lympho-vascular invasion, perineural invasion and lymph node metastasis were assessed. Ki-67 immunohistochemistry were performed. Mean ±SD age of the patients was 58.9±13.8 years. Among the morphological variants, 64% cases were microscopically arranged in papillary pattern. Eighteen (50%) patients underwent surgical intervention at stage pT2. Lympho-vascular invasion, perineural invasion and lymph node metastasis were identified in 12 (33.3%), 9 (25%) and 13 (48.1%) of the cases, respectively. Among the morphological parameters, Ki-67 shows association with pathological stages and lymph node metastasis. The use of Ki-67 immunomarker along with grading and staging may provide significant prognostic information in urothelial carcinoma of the urinary bladder. BSMMU J 2022; 15(3): 186-191

Ultrasound signs of ovarian tumors according to a standardized protocol

Objective: to identify the characteristic echographic features of benign ovarian tumors using the recommendations of the IOTA group.Materials and methods. Five articles published in the journal Ultrasound in Obstetrics & Gynecology for 2008–2019 were analyzed. Each article is devoted to a histologically verified pathology of the ovaries, representing four morphological variants of an ovarian tumor (strum, fibroma/fibrothecoma, uroepithelial tumor (Brenner's tumor) and cystadenofibroma, as well as endometrioma in pregnancy. The total number was 380 women. When describing pathological formations, the researchers used a single protocol recommended by the IOTA group. Evaluated twentyone parameters, including the morphology of the formation, the structure of fluid inclusions and the solid component, the presence of fluid in the retrouterine space and ascites, as well as the degree of tumor vascularization.Results. The analysis of the struma, fibroma (fibrothecoma), Brenner tumor, cystadenofibroma and endometrioma of pregnant women indicates that there are no reliable criteria for diagnosing the histological structure of the tumor, both by the age of the patients, the size of the formation, and by ultrasound signs. Hyperechoic inclusions, which are noted only in Brenner tumors, both benign and malignant, can serve as the only marker among the pathology under consideration. In the study of the listed benign neoplasms of the ovaries, no features of the blood supply were revealed. All neoplasms had vascularization from the complete absence of vessels (1 point) to their moderate number (3 points). Hypervascularization (4 points) occurred in struma, fibroma (fibrotecoma), and cystadenofibroma.Conclusions. The task of ultrasound examination is the timely detection of an ovarian tumor with a presumptive conclusion of the probability of malignancy, based on standardized protocols of the IOTA group, which is important for the correct routing of the patient.

NAMES OF ADMINISTRATIVE AND LEGAL ACTS AND DOCUMENTS IN THE DICTIONARY OF THE UKRAINIAN LANGUAGE OF THE 16TH ‒ FIRST HALF OF THE 17TH CENTURIES

The article provides a linguistic analysis of the composition, semantics, origin, and the historical development of the terms used to denote the names of administrative and legal acts and documents in the Old Ukrainian language. The study was carried out on the basis of the «Dictionary of the Ukrainian Language of the 16th – First Half of the 17th Centuries». The Polish influence on the contemporary administrative and legal vocabulary, mainly represented in documentation, as well as in confessional, scientific, journalistic, and conversational styles, is traced. The phenomenon of polysemy and synonymy in the terminological system is revealed, and structural models of terminological compounds are also considered. It has been established that the names of administrative and legal acts and documents in the Old Ukrainian language are also terms-words that can be monosemous (интерцыза, контрактъ, инструкция etc.) and polysemous (записъ, мандатъ), and terminological phrases that are not characterized by polysemy. In addition to borrowed terms, lexemes of Slavic origin have also been recorded (листъ, записъ). A lot of nouns formed with the help of substantive-adjective phrases, in which nouns are the most active main words, have been recorded листъ (83), записъ (11), актъ (8). The order of words in terminological phrases can also be indirect, which gave us reason to single out inversion options (листъ веновный, вѣновный листъ; листъ вызнаный, вызнаный лист; запись продажный, продажный записъ etc.). Attention is also drawn to the fact that both words-terms and terminological phrases can enter into synonymous relations (контрактъ‒интерцыза; карта‒листъ; квитъ‒квитация‒записъ; записъ выдеркафовый‒ конътрактъ видеркафовый; квитовный записъ‒ квитовный листъ etc.). A morphological variant is also singled out квитъ ‒ квита. Having traced the historical development of the terms of the studied period, it was noted that most of them did not disappear from circulation, were replaced by orthographic or word-forming variants, but underwent mainly transformations of semantics, such as the expansion of the semantic structure, acquisition of additional meanings, narrowing of semantics, or disappeared from circulation, became obsolete and changed the scope of their use, living only in dialects or in colloquial style. Keywords: term, terminological combination, document, semantics, etymology, historical development, structure, system connections, style.

Extraosseous Ectopic Meningioma on Temporoparietal Region Mimicking a Soft Tissue Tumour: A Case Report

Ectopic meningiomas are very rare tumour entities that account for approximately 1-2% of all meningiomas and appear extracranially mostly in the head and neck region. Usually they create diagnostic confusion in an ectopic site with other soft tissue neoplasms, mostly peripheral nerve sheath tumors, myogenic tumours and vascular tumours, more so, with morphological variants like fibroblastic, angiomatous, etc. that may not show the meningothelial cells conspicuously. Here authors report one such case of a 55-year-old female, presenting with a slowly growing non tender left temporal mass since childhood that was thought to be a myogenic tumour on Computed Tomography (CT) scan but on microscopy was a transitional meningioma with mixed fibroblastic and meningothelial pattern. Hence, ectopic meningioma is one of the imperative diagnosis that a pathologist should keep in mind while dealing with soft tissue neoplasms of the head and neck region.

Варианты морфологии и расположения карины бифуркации трахеи: данные бронхоскопии

Варианты морфологии и расположения карины бифуркации трахеи: данные бронхоскопии

Microcystic Meningioma - A Diagnostic Dilemma During Intraoperative Squash Smear Study.

Meningiomas are generally slow-growing, benign, and non-infiltrating in nature. They are usually easy to diagnose cytologically if they are of the meningothelial type; however, they may cause diagnostic challenges when they manifest as unusual morphological variants, like the microcystic type. Because of the rarity of microcystic meningioma (MM), information on its cytological features is rarely available in the literature. The goal of this study is to review the cytological features of MM in crush preparations prepared at the time of intra-op consultation and to identify the more common features which are helpful in rendering a correct diagnosis. Cytological features of five cases of MM were reviewed and noted from the records. There were five patients of MM with a male: female ratio of 1.5:1 and a mean age of 52 years. All tumors were supratentorial and dura-based. Magnetic resonance imaging (MRI) showed low signal intensity on T1 and high signal intensity on T2 weighted images in four cases. Cytosmears were moderate-to-highly cellular. There were variable-sized cystic spaces within the meningothelial cell clusters. In four cases, nuclear pleomorphism was frequently observed. Nuclear pseudoinclusions, atypical mitoses, vascular proliferation, and necrosis were absent in all cases. Whorling and psammoma bodies were seen in only one case. Cytological features identified would be helpful in the diagnosis of microcystic meningiomas, especially in unusual radiological findings. Their unusual cytological features might lead to problems in differential diagnosis from other intracranial tumors, including glioblastoma, metastatic tumor, etc.

Plasmacytoid urothelial carcinoma - A clinicopathological case series of an aggressive variant of urothelial cancer.

Many new morphological variants of urothelial carcinoma of urinary bladder have been described in the literature, plasmacytoid/signet ring cell/diffuse variant being one of the rare amongst these. Till date, no case series has been reported from India, describing this variant. We retrospectively analyzed the clinicopathological data of 14 patients diagnosed at our center with plasmacytoid urothelial carcinoma. Seven cases (50%) were pure forms while the remaining 50% of cases had a concurrent conventional urothelial carcinoma component. Immunohistochemistry was performed to rule out other mimickers of this variant. Treatment-related data were available for seven patients, while follow-up was available for nine cases. Overall, plasmacytoid variant of urothelial carcinoma is considered to be an aggressive tumor with poor prognosis.

Large Duct Pancreatic Ductal Adenocarcinoma: A Morphological Variant of Pancreatic Ductal Adenocarcinoma With Distinct CT and MRI Characteristics.

To investigate the imaging characteristics of large duct pancreatic ductal adenocarcinoma (LD-PDAC) on computed tomography (CT) and magnetic resonance imaging (MRI). Thirty-five patients with LD-PDAC (63.2 ± 9.7 years) were retrospectively evaluated. Tumor morphology on CT and MRI (predominantly solid mass vs. solid mass with prominent cysts vs. predominantly cystic mass) was evaluated. Additionally, the visibility, quantity, shape (oval vs. branching vs. irregular), and MRI signal intensity of neoplastic cysts within the LD-PDAC were investigated. The radiological diagnoses rendered for LD-PDAC in radiology reports were reviewed. LD-PDAC was more commonly observed as a solid mass with prominent cysts (45.7% [16/35] on CT and 37.1% [13/35] on MRI) or a predominantly cystic mass (20.0% [7/35] on CT and 40.0% [14/35] on MRI) and less commonly as a predominantly solid mass on CT (34.3% [12/35]) and MRI (22.9% [8/35]). The tumor morphology on imaging was significantly associated with the size of the cancer gland on histopathological examination (P = 0.020 [CT] and 0.013 [MRI]). Neoplastic cysts were visible in 88.6% (31/35) and 91.4% (32/35) of the LD-PDAC cases on CT and MRI, respectively. The cysts appeared as branching (51.6% [16/35] on CT and 59.4% [19/35] on MRI) or oval shapes (45.2% [14/35] on CT and 31.2% [10/35] on MRI) with fluid-like MRI signal intensity. In the radiology reports, 10 LD-PDAC cases (28.6%) were misinterpreted as diseases other than typical PDAC, particularly intraductal papillary mucinous neoplasms. LD-PDAC frequently appears as a solid mass with prominent cysts or as a predominantly cystic mass on CT and MRI. Radiologists should be familiar with the imaging features of LD-PDAC to avoid misdiagnosis.

Патогенетические и структурно-функциональные изменения в почках после перенесенного COVID-19

There is now a growing evidence of the long-term effects of COVID-19, affecting almost all human systems and organs, including the kidneys. The objective of this paper was to study pathogenetic and structural and functional changes in the kidneys in patients with COVID-19 infection. Materials and methods. Articles were searched in PubMed, Medline, Google Scholar, E-library, Clinical Trial databases using the keywords "post-COVID syndrome," "renal damage (kidney disease)," "COVID-19," "SARS-CoV-2," and "glomerulonephritis" in Russian and English. Databases reporting cases of detectable renal damage following a prior coronavirus infection published by September 28, 2022 were used. This review includes literature reviews, clinical cases, and original studies reporting the confirmed cases of detectable renal damage after confirmed prior COVID-19. The sources that focus only on renal damage during the acute period of coronavirus infection have been excluded. Results. Primary viral damage is carried out through the effect on the receptors of angiotensin-converting enzyme-2 (ACE-2). No less important mechanisms of viral damage are immunological and inflammatory reactions, dysfunctions of the complement system, leading to multiple organ failure. The long-term consequences of coronavirus infection on the kidneys were manifested in a decrease in the estimated glomerular filtration rate (eGFR), an increase in creatinine levels, proteinuria, and microhematuria. Dickkopf-3 protein (uDKK-3) may become a promising marker of kidney damage. Post-COVID renal disease can occur both de novo and with a previous renal complication of COVID-19. The most common morphological variants of kidney damage were tubular lesions and various morphological variants of glomerulonephritis. Conclusion. The association of COVID-19 and kidney damage in the post-COVID period is supported by common mechanisms of pathogenesis, including direct viral damage through ACE-2, inflammatory and immune reactions of the body. These data are confirmed by detectable markers of inflammation and damage to the renal tissue, the morphological picture of necrosis, fibrosis of the renal parenchyma in patients with COVID-19 infection.

SEMANTIC-SYNTACTIC EXPLICATION OF THE VALENCE POTENTIAL OF THE VERB- TERMS АКОМПАНУВАТИ AND ДИРИГУВАТИ

The article examines the valence potential of verb-terms акомпанувати and диригувати. The three-component nature of their valence framework was substantiated, and the main lexical-semantic groups of words that explain all non-predicate arguments were defined. Typical morphological variants of addressee, object, and instrumental arguments were also established. It was found that the verb акомпанувати generates three non-predicate valenceconditioned components: the subject of the action (the person who performs the accompaniment), the addressee of the action (a musician or group of musicians who are accompanied), the instrument of action (actually a musical instrument on which a melody is performed for accompaniment). The subject component dependent on the verb акомпанувати is expressed by the names of persons (proper and common) either quantified or unquantified sets of persons who accompany. The instrumental component, which is determined by the verb акомпанувати, is most consistently realized by the names of musical instruments. It was emphasized that the verb акомпанувати is intransitive, therefore it can’t determine the object component, despite its synonymy with the transitive verb супроводжувати (orchestra, choir, etc.). The trivalency of the verb-term диригувати has been established. The non-predicate components of the subject of the action (the person who conducts), of the object of the action (a piece of music that is conducted), and of the instrument of the action (an instrument used to conduct) in its valence environment. Among all the components that cause the verb диригувати, the object of action has the broadest lexical-semantic content, represented by proper and general names of musical groups, works, and their fragments. A conclusion was made about the semi-obligatory usage of the instrument of the action with the verb акомпанувати and the optional usage with the verb диригувати, the difference in its lexical-semantic expression was noted. The instrumental component, which is determined by the verb акомпанувати, is most consistently implemented by the names of musical instruments; in the verb диригувати it is lexically limited by the nouns hand and stick.

A Case-Control Study of Serum and Tissue Catalase among Morphological Variants of Vitiligo.

Role of oxidative stress in the pathogenesis of vitiligo. Estimation of serum and tissue catalase levels in morphological variants of vitiligo. A prospective case-control study was conducted in the outpatient department of Dermatology in Safdarjung hospital. We estimated levels of serum and tissue catalase in 30 vitiligo patients and 30 matched healthy controls. The data analysis was done in Statistical Package for Social Sciences (SPSS) version 21.0. Normality of data was tested by Kolmogorov-Smirnov test. Serum and tissue catalase was lower in vitiligo patients than controls. Serum catalase was lowest in vulgaris type, whereas in the acrofacial type had lowest tissue catalase levels. Vitiligo patients have a generalized oxidative stress functioning at a higher pace as seen with decreased serum and tissue CAT which can well be taken as a marker of active disease and they can be helped with topical pseudoCAT preparations.

THE VALUE OF MUTATIONS IN THE ASXL1 GENE IN THE ONCOGENESIS OF ACUTE MYELOID LEUKEMIA IN ADULTS

The aim was to evaluate the significance of the ASXL1 gene mutations in the oncogenesis of acute myeloid leukemia (AML) in adults. Materials and methods. Bone marrow and peripheral blood samples of 49 patients with AML aged from 18 to 84 years, treated at the Sverdlovsk regional hematological center, were examined, including those with a morphological variant of AML M0 – 3, M1 – 4, M2 – 19, M3 – 6, M4 – 10, M5 – 1, M6 – 1, M7 – 1, blast plasmacytoid dendritic cell neoplasm – 1, acute hybrid leukemia – 2, AML after chronic myeloproliferative disease (CMPD) – 2. Mutations in the ASXL1 gene were detected in peripheral blood and bone marrow samples by direct RNA sequencing (n=26) and high-throughput DNA sequencing (n=23) on automatic genetic analyzers ABI Prism 310 and MiSeqDX, respectively. Results. It was found that pathogenetically significant mutations of the ASXL1 gene were detected in 16.3% of samples with AML M0, M2, M4, AML from CMPD and acute hybrid leukemia. The distribution of ASXL1 anomalies was as follows: deletion n. Del (1755;2007) — 4, duplication c.1934dupG — 3, non-synonymous transversion c.1348A>T — 1. Along with lesions of the ASXL1 gene, quantitative and structural chromosomal aberrations were determined in these samples, including del(5)(q13), t(8;21)(q22;q22), t(9;22)(q34;q11), as well as point mutations in the CEBPA, IDH2, NRAS, RUNX1, SRSF2, TET2 genes, internal tandem duplication in the FLT3 gene. This indicates the cooperation of two or more mutational events in the oncogenesis of ASXL1-positive AML, which can determine the different reaction of the tumor to chemotherapeutic treatment and the prognosis of the disease.

Variant selection and morphology by the different cooling rates in Zr-xNb-0.4Mo alloys

Although many efforts have been made on understanding the variant selection rules, the interplay of these rules and their combined effects on variant selection have not been well addressed. In this work, variant selection and morphology by the different cooling rates in Zr-xNb-0.4Mo (x=0.2, 0.6 and 1.0 wt.%) alloys are characterized using scanning electron microscopy (SEM) and electron backscatter diffraction (EBSD) technique. The results show that the variation of variant selection and morphology is attributed to the Nb content, the parent β grain size, the cooling rate, the β grain boundary (GB) characteristics and the interplay among them. The Nb addition (Nb≤0.6 wt.%) decreases the average grain size of parent β grains, and the smaller parent β grain size generally results in the larger degree of variant selection (DVS) values in the individual parent β grain due to their resistance to the uniform nucleation and growth of α-variants. The slow cooling rate promotes the diffusional transformation and favors the formation of special β GBs and the β GBs with high dislocation density, which usually lead to a stronger DVS in the individual parent β grains. The very large weighted area percentage of α-variant in the individual parent β grains, which accounts for the stronger DVS in the individual parent β grains, is due to the special β GBs, the β GBs with high dislocation density and the incomplete martensitic transformation (martensitic-diffusional mixed transformation). The β GB with high dislocation density has a larger contribution to the strong DVS of individual parent β grains than the special β GB. In addition, the result shows that the low density of statistically stored dislocations (SSDs) can inhibit the nucleation and growth of the α-variant produced by the special β GB.

The lateral ulnar collateral ligament: Anatomical and structural study for clinical application in the diagnosis and treatment of elbow lateral ligament injuries.

The lateral ulnar collateral ligament (LUCL) is considered one of the main stabilizers of the elbow. However, its anatomical description is not well established. Imaging techniques do not always have agreed upon parameters for the study of this ligament. Therefore, herein, we studied the macro and microanatomy of the LUCL to establish its morphological and morphometric characteristics more precisely. Fifty-five fresh-frozen human elbows underwent dissection of the lateral collateral ligament. Morphological characteristics were studied in detail. Ultrasound (US) and magnetic resonance (MR) were done before dissection. Two specimens were selected for PGP 9.5 S immunohistochemistry. Ten additional elbows were analyzed by E12 sheet plastination. LUCL was identified in all specimens and clearly defined by E12 semi-thin sections. It fused with the common extensor tendon and the radial ligament. The total length of the LUCL was 48.50 mm at 90°, 46.76 mm at maximum flexion and 44.10 mm at complete extension. Three morphological insertion variants were identified. Both US and MR identified the LUCL in all cases. It was hypoechoic in the middle and distal third in 85%. The LUCL was hypointense on MR in 95%. Free nerve endings were present on histology. The LUCL is closely related to the anular ligament. It is stretched during flexion and supination. US and MR can reliably identify its fibers. Anatomical data are relevant to the surgeon who repairs the ligaments of the elbow. Also, to the radiologist and pain physician who interpret imaging and treat patients with pain syndromes of the elbow.

Synchronous sinonasal tumour: double trouble?

Schneiderian papilloma is a benign sinonasal tumour, which has three morphological variants: fungiform, inverted and oncocytic. Inverted papilloma, being the most prevalent variant, is three times more common among males in their fifth to seventh decade of life. On the other hand, nasopharyngeal carcinoma is a malignant tumour arising from the nasopharyngeal epithelium. Albeit rare, synchronous sinonasal tumour has been reported and remains a quandary till date, especially when it involves malignant and benign synchronous nasal mass. In this paper, we reported a case of a successfully treated synchronous sinonasal inverted papilloma with nasopharyngeal carcinoma in an elderly male. We would like to highlight the need to investigate suspicious bilateral nasal masses due to the possible coexistence of two different pathologies, as in our case.

Identification of the genes encoding candidate septate junction components expressed during early development of the sea urchin, Strongylocentrotus purpuratus, and evidence of a role for Mesh in the formation of the gut barrier

Septate junctions (SJs) evolved as cell-cell junctions that regulate the paracellular barrier and integrity of epithelia in invertebrates. Multiple morphological variants of SJs exist specific to different epithelia and/or phyla but the biological significance of varied SJ morphology is unclear because the knowledge of the SJ associated proteins and their functions in non-insect invertebrates remains largely unknown. Here we report cell-specific expression of nine candidate SJ genes in the early life stages of the sea urchin Strongylocentrotus purpuratus. By use of in situ RNA hybridization and single cell RNA-seq we found that the expression of selected genes encoding putatively SJ associated transmembrane and cytoplasmic scaffold molecules was dynamically regulated during epithelial development in the embryos and larvae with different epithelia expressing different cohorts of SJ genes. We focused a functional analysis on SpMesh, a homolog of the Drosophila smooth SJ component Mesh, which was highly enriched in the endodermal epithelium of the mid- and hindgut. Functional perturbation of SpMesh by both CRISPR/Cas9 mutagenesis and vivo morpholino-mediated knockdown shows that loss of SpMesh does not disrupt the formation of the gut epithelium during gastrulation. However, loss of SpMesh resulted in a severely reduced gut-paracellular barrier as quantitated by increased permeability to 3–5 ​kDa FITC-dextran. Together, these studies provide a first look at the molecular SJ physiology during the development of a marine organism and suggest a shared role for Mesh-homologous proteins in forming an intestinal barrier in invertebrates. Results have implications for consideration of the traits underlying species-specific sensitivity of marine larvae to climate driven ocean change.

Field Performance of Disease-Free Plants of Ginger Produced by Tissue Culture and Agronomic, Cytological, and Molecular Characterization of the Morphological Variants

Ginger (Zingiber officinale Rosc.) is an important spice crop valued for its flavored and medical properties. It is susceptible to soil-borne diseases, which can cause considerable economic loss to growers. In vitro culture is feasible for the propagation of disease-free ginger plants, but has several disadvantages when producing seed rhizomes that can be commercially used, such as long cultivation cycles (usually 2–3 years) and occurrence of somaclonal variation. In this study, dynamic changes in the morphological characteristics of in vitro-propagated disease-free plants of ‘Wuling’ ginger were evaluated by continuous observation and measurement at 30-day intervals, and morphological variants were screened and characterized by agronomic, cytological, and molecular analysis at harvest. Results showed that the plants grew rapidly within 120 days after planting, and the most active growth period was from 60 to 120 days. Eight plants with clear and stable morphological differences were screened out from approximately 2000 plants grown in the field, and they could be classified into two groups (VT1 and VT2) based on tiller number, plant height, leaf color, and leaf shape. By flow cytometry analysis and chromosome counting, the VT1 was confirmed to be diploid, with the shortest plant height, the largest number of tillers and rhizome knobs, and the smallest tiller diameter and rhizome size among the three types of plants. The VT2 was mixoploid, consisting of diploid and tetraploid cells, with significantly reduced tiller number and rhizome knobs, significantly larger stomatal guard cells/apertures, and significantly lower stomatal density. SSR analysis detected DNA band profile changes in six out of the eight variants, including one plant of the VT1 and all the VT2 plants. The findings of this study might contribute to the commercial production of disease-free seed rhizomes in ginger, and the characterized somaclonal variants could provide useful germplasm resources for future breeding.

The Choice of Optimally Necessary Devices for Endovascular Treatment of Coarctation of the Aorta

The aim. To determine the optimally necessary devices for endovascular stenting of coarctation of the aorta (CoA), considering the anatomical features of the defect and the age of the patient.
 Materials and methods. Examination and endovascular treatment of 189 patients aged 5 to 60 years with CoA of different anatomical and morphological variants was performed.
 Results and discussion. We presented the clinical features of different anatomical andmorphological variants of CoA. Endovascular treatment of CoA with stenting is considered the best method for adolescents and adults, due to the lower risk of aneurysm formation compared to balloon angioplasty. We were able to successfully reduce the invasive pressure gradient in patients of different ages and to establish dependence of the frequency of complications on the type of the stent used. There were no cases of in-hospital death. The effectiveness of the intervention was 99.4 %. All the patients were discharged from the hospital in good condition 3-7 days (3.3 ± 1.9 days) after the procedure. Currently, 95.7 % are being followed up. During the 5-year follow-up period, 1 patient died due to concomitant heart failure, heart rhythm disturbances (atrial fibrillation) and mitral insufficiency. There were 10.1 % patients (n = 19) with complications: 4.9 % (n = 4) with open-cell stents, 12.1 % (n = 13) with closed-cell stents, 2.2 % (n = 4) with stent-grafts, 7.9 % (n = 16) with uncovered stents. The frequency of reinterventions was 45.0 % in patients older than 25 years, 37.2 % in those aged 5-18 years and 17.6 % in those aged 19-25 years.
 Conclusions. The choice of optimally necessary devices for endovascular stenting of the aorta is recommended to be carried out considering the anatomical features of the defect and the age of the patient.

NOMINATION OF ATMOSPHERIC PRECIPITATION, PROCESSES AND CONCEPTS RELATED TO WATER FREEZING

Names of atmospheric precipitation resulting from water freezing were studied on the examples of eastern steppe dialects of the villages: Husarka, Bilmanka of the Zaporizhzhia region and the village of Temryuk of the Donetsk region.
 The article describes names for the first fall of snow in autumn, a snow-covered road, shovelful snow, snowy winter, names of deep, loose snow, blizzard, snowfall without wind, tent, snow slide, snowflakes, icicles, a layer of snow on tree bark large icicles, icicles, ice, frozen water, frost, small hail, the phenomenon of sliding (skating) on ice, freezing of snow, etc. The comments of residents contribute to a circle of representatives associated with water in the solid state. The study clarifies the specifics of some names and varieties of certain phenomena, etc.
 Commonly used lexemes or their phonetic, word-forming, morphological variants were found in the thematic vocabulary group: bu'rulka, za'met, kuchu'hura, ozhey'ledytsa, plys'ty, cha'lapaty, etc.; borrowings from contact languages: supolka (phonetical variant – su'pelka), so'sulka (phonetical variant – soa'sulka), suh'rob, mi'tel, constructions za'morzli 'vokna, narisu'vala zi'ma, etc. Certified nominations are mostly one- and two-component, less often descriptive constructions.
 Concerning the names that have counterparts in other dialects, parallels with the identical (metil ‘khurtovyna’, valyty ‘snizhyty’, peremót ‘peremet’, lod ‘lid’, etc.) and distinctive (suróvyi ‘raw, uncooked’, ‘stern, demanding of oneself and others’, peremét ‘a fishing tackle with many hooks, which was set across the stream’, draw ‘make folds in a skirt, dress; corrugation’, ‘invent, suggest something to oneself’, etc.) values have been found.

Recircumscription of Utricularia leptorhyncha and U. lasiocaulis and three related new species for northern Australia

The Utricularia lasiocaulis F.Muell. complex (subg. Polypompholyx; sect. Lasiocaules) is a morphologically and ecologically variable group of closely related taxa with a mostly tropical distribution across northern Australia. A recent molecular phylogenetic study placed the recognised species U. kamienskii F.Muell. sister to a clade of accessions relegated to either U. leptorhyncha O. Schwarz or U. lasiocaulis, with the latter previously circumscribed as an assemblage of highly variable morphological forms. We have expanded the previous study to include populations representing the known distributions of all three species and have attempted to include all morphological variants; 55 ingroup accessions were used in the full phylogenetic analysis based on two non-coding chloroplast regions (rps16, trnD–T) and the nuclear ribosomal internal transcribed spacer (ITS). We found that the pink corolla form of the usually white flowered U. kamienskii is not sufficiently different, and we retain it under that species. We also found strong support for a paraphyletic U. leptorhyncha, with the smaller flowered accessions matching the type material placed sister to all other U. lasiocaulis forms, including a grouping previously assigned as a larger flowered U. leptorhyncha. Within the U. lasiocaulis clade we found that much of the variation sorts into well-supported clades that we find are sufficiently morphologically and genetically differentiated from the type clade for recognition at the specific rank, namely Utricularia brennanii R.W.Jobson & Baleeiro from Northern Territory and Queensland, Utricularia cowiei R.W.Jobson & Baleeiro from the Kimberley region of Western Australia, and U. disjuncta R.W.Jobson & Baleeiro restricted to the Darwin and Gulf region of the Northern Territory.