A direct bidirectional current discharge path between the input/output (I/O) and ground (GND) is essential for the robust protection of charging device models (CDM) in the tightly constrained design parameters of advanced low-voltage (LV) processes. Dual-direction silicon controlled rectifiers (DDSCRs) serve as ESD protection devices with high efficiency unit area discharge, enabling bidirectional electrostatic protection. However, the high trigger voltage of conventional DDSCR makes it unsuitable for ASICs used for the preamplification of biomedical signals, which only operate at low supply voltage. To address this issue, a self-biased triggered DDSCR (STDDSCR) structure is proposed to further reduce the trigger voltage. When the ESD pulse comes, the external RC trigger circuit controls the PMOS turn-on by self-bias, and the current release path is opened in advance to reduce the trigger voltage. As the ESD pulse voltage increases, the SCR loop opens to establish positive feedback and drain the amplified current. Additionally, the junction capacitance is decreased through high-resistance epitaxy and low-concentration P-well injection to further lower the trigger voltage. The simulation results of LTspice and TCAD respectively demonstrate that ESD devices can clamp transient high voltages earlier, with low parasitic capacitance and leakage current suitable for ESD protection of high-speed ports up to 1.5 V under normal operating conditions.