In this paper we propose a scheme to generate tunable 16 μm radiation from CO2 molecules by cascade lasing. The stimulating 9.5 μm radiation is generated internally by the fast rotating mirror Q-switching technique. The optical scheme proposed by us uses an intracavity prism to separate the 9.5 μm and the 16 μm beams. This facilitates independent tuning of the two beams if required. In the present configuration, only the 16 μm cavity is dispersive. The 9.5 μm beam grows spontaneously in a stable semiconfocal resonator. We have developed a theoretical model to simulate the proposed scheme. The model predicts the energy and power of 16 μm radiation. The calculated values are much higher than the previously obtained experimental values. The results point out the feasibility of developing a laser system based on the theoretical design parameters presented in this paper. Such laser systems can find application in uranium isotope separation studies.