The influence of optical radiation power on the one-decibel compression point, harmonic distortion and dynamic range due to interference in a fiber-optic transmission line of an ultra-high frequency (microwave) signal has been studied. The line had a positive microwave signal transmission coefficient, and there were no amplification elements between the input and output. The amplification effect was achieved through the use of increased power of the carrier optical radiation and a photodetector with a high photocurrent. It has been shown that an increase in optical radiation power leads to a decrease in one-dB compression power and an increase in harmonic distortion, but an increase in optical radiation power does not lead to a change in the dynamic range of interference. It was found that the dynamic range free from interference was about 85…87 dB.