Methoxychalcone Research Articles

ChemInform Abstract: SYNTHESIS OF PISCERYTHRONE

AbstractAus (Ia) erhält man das Acetat (Ib), das über eine oxidative Umlagerung mit Thalliumnitrat in Methanol und anschließende Hydrolyse mit verd. Salzsäure sowie Hydrogenolyse in das Isoflavon (II) umgewandelt wird, aus dem in weiteren Schritten die gesuchte Verbindung (III) zugänglich gemacht wird.

SYNTHESIS OF PISCERYTHRONE

Abstract 5,7,2′,4′-Tetrahydroxy-5’-methoxyisoflavone (6) prepared from 2,4,2′,4′-tetrabenzyloxy-6’-hydroxy-5-methoxychalcone (2) by way of three steps was partially benzoylated to give 7-benzoyloxy-5,2′,4′-trihydroxy-5′-methoxychalcone (7). The condensation of 7 with 2-methyl-3-buten-2-ol afforded 7-benzoyloxy-5,2′,4′-trihydroxy-5′-methoxy-3′-(3-methyl-2-butenyl) isoflavone (8), which was hydrolyzed to give piscerythrone (1).

Cardamonin and alpinetin from the seeds of Amomum subulatum.

We report in this communication the isolation of cardamonin (2', 4'-dihydroxy–6'-methoxy chalcone) and alpinetin (7–hydroxy–5–methoocy flavanone) from the seeds of Amomum subulatum Roxb. (Zingiberaceae). An earlier chemical investigation on the seeds [1] revealed the presence of a number of terpenes.

Chalcones of Flemingia chappar ham : The structure and synthesis of flemichapparin

From the whole plant of Flemingia chappar Ham, two crystalline chalcones have been isolated. The major one has been characterised as 2′,4′-dihydroxychalcone (II) and the structure of the minor one, a new naturally occurring chalcone named flemichapparin, has been established as 2′,4′-dihydroxy-5′-methoxychalcone (VI) from spectral, chemical and synthetic evidence.