The main purpose of this paper is to refute the ‘methodological continuity’ argument supporting epistemic realism in metaphysics. This argument aims to show that scientific realists have to accept that metaphysics is as rationally justified as science given that they both employ inference to the best explanation, i.e. that metaphysics and science are methodologically continuous. I argue that the reasons given by scientific realists as to why inference to the best explanation (IBE) is reliable in science do not constitute a reason to believe that it is reliable in metaphysics. The justification of IBE in science and the justification of IBE in metaphysics are two distinct issues with only superficial similarities, and one cannot rely on one for the other. This becomes especially clear when one analyses the debate about the legitimacy of IBE that has taken place between realists and empiricists. The metaphysician seeking to piggyback on the realist defense of IBE in science by the methodological continuity argument presupposes that the defense is straightforwardly applicable to metaphysics. I will argue that it is, in fact, not. The favored defenses of IBE by scientific realists make extensive use of empirical considerations, predictive power and inductive evidence, all of which are paradigmatically absent in the metaphysical context. Furthermore, even if the realist would concede the methodological continuity argument, I argue that the metaphysician fails to offer any agreed upon conclusions resulting from its application in metaphysics.