You have accessJournal of UrologyProstate Cancer: Epidemiology & Natural History I1 Apr 2018MP21-19 THE PREVALENCE AND BIOPSYCHOSOCIAL PREDICTORS OF SUICIDALITY IN MEN WITH PROSTATE CANCER Jason Izard, D. Robert Siemens, Phylicia Verreault, Angela Black, and Dean Tripp Jason IzardJason Izard More articles by this author , D. Robert SiemensD. Robert Siemens More articles by this author , Phylicia VerreaultPhylicia Verreault More articles by this author , Angela BlackAngela Black More articles by this author , and Dean TrippDean Tripp More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2018.02.710AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Prostate cancer (PCa) is associated with depression above levels reported in the general population. There is a positive association between PCa diagnosis and suicide. The first aim of this study is to establish a point prevalence for suicidality among patients diagnosed with PCa. The second aim is to evaluate what biopsychosocial variables best predict greater risk of suicidality in men with PCa. METHODS Participants were recruited from the ambulatory PCa clinics at Queen′s University and through direct invitation from an online PCa support group (Prostate Cancer Canada). All willing participants were directed to the online survey. Hierarchical regression was used to predict suicidality (SBQ-R), with stage of PCa, length of diagnosis, number of comorbidities, number of treatments, exposure to suicide, functional, emotional and social well-being subscales of the FACT-P, hopelessness, stress catastrophizing, fears about death, and perceived interpersonal burdensomeness and thwarted belongingness scales (INQ-10). RESULTS At time of submission, 243 participants completed the survey. Of those 77% of participants were diagnosed with localized PCa and 23% with advanced PCa. The most common treatments received were prostatectomy (63%), radiotherapy (42%), and androgen-deprivation therapy (37%). In regard to suicidality, 16.9% were classified as at-risk cases using a general population cut-score, while 10.3% were classified as at-risk cases using an inpatient population cutoff. The regression analyses indicated that greater hopelessness (β=0.32) was the strongest predictor of suicidality. Previous exposure to suicide (β=0.26), reduced functional wellbeing (β=-0.21), higher exposure to suicide (β=0.26), shorter length of diagnosis (β=-0.16) and greater perceived burdensomeness (β=0.23) were all associated with increased suicidality. Cancer stage was not a significant predictor of suicide behaviors. CONCLUSIONS Although exposure to suicide, length of diagnosis and reduced functional well-being were associated with greater suicidality, perceived burdensomeness, or the extent to which individuals perceived themselves as burden for their family and friends, and hopelessness appear to be more salient clinical targets. Screening and identifying troublesome cognitive patterns in patients with PCa may be beneficial in reducing suicidality. © 2018FiguresReferencesRelatedDetails Volume 199Issue 4SApril 2018Page: e270 Advertisement Copyright & Permissions© 2018MetricsAuthor Information Jason Izard More articles by this author D. Robert Siemens More articles by this author Phylicia Verreault More articles by this author Angela Black More articles by this author Dean Tripp More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...
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