Quantum transport in materials describes the behavior of particles at the quantum level. Topological materials exhibit nontrivial transport properties with topological invariants, leading to the emergence of protected states that are immune against disorders at the material boundaries. In many real-world materials, especially those with anisotropic crystal structures, the transport properties can vary significantly along different directions within the material bulk. Here, we experimentally observe counterintuitive quantum transport phenomena in anisotropic topological insulators with controllable anisotropy and disorder, implemented on a programmable topological photonic chip. We examine phase transition from the topological phase to the Anderson phase, between which a new quasi-diffusive phase emerges. Anisotropic topological transport demonstrates unconventional superior robustness in the bulk mode compared to the edge mode, in the presence of disorder and loss in realistic systems. Peculiar topological transport with sophisticated gradient anisotropy, emulating stretched topological materials, occurs at the gradient domain wall that can be reconfigured. Our findings provide fresh insights into the intricate interplay between anisotropy within the bulk and robustness at the boundary of topological materials, which could lead to advancements in the field of topological material science and the development of topological devices with tailored functionalities.