Purpose: To report any epidemiological, anatomo-clinical and therapeutic aspects of maxillary ameloblastoma at the Yalgado Ouedraogo University Hospital (CHU-YO). Materials and Method: This was a descriptive and retrospective study covering the period ranging from January 1, 2010 to December 31, 2016. All patients received in the stomatology department for maxillary ameloblastoma with histological confirmation were included in the study. Consultation registers were used as the basis for data collection. Results: In our study, 50 cases were reported, i.e. an incidence of 7.14 cases per year. The mean age was 30.16 years with a sex ratio of 0.56. Housewives were the most affected and the average time to consultation was 2.5 years. The site of the tumor was in the majority of cases the mandible 82%, with swelling as the main reason for consultation. X-rays showed a predominance of monogeodic images in 56% of the cases. Conservative surgery was performed in 56% of the cases. Conclusion: Ameloblastoma is common in our area, characterized by delayed consultation. Strengthening of the technical facilities and awareness campaigns for the populations for early consultation are required.