Abstract
Introduction: Acute post-infectious glomerulonephritis (APIGN) can be serious due to its complications that still occur in our countries. In this work, we aimed to study the epidemiological, clinical, biological and evolutionary aspects of APIGN. Patients and methods: We conducted a retrospective, descriptive study from January 1st, 2015 to December 31st, 2017 in the pediatric ward of the Gabriel Touré Teaching Hospital in Bamako. All children hospitalized for APIGN were included. Results: In two years, we included 10 children aged 7 years old on average; all from low socioeconomic backgrounds. The sex ratio was 1.5. On average, the children spent 15.8 days before our consultation. Edema was the main reason for consultation. We found a history of infection and high blood pressure in 30% each, and renal failure in 10% of the children. Hematuria and proteinuria were detected in 100% and 90%, respectively. Hypocomplementemia was observed in 66.6%. One third of the children had a positive antistreptolysin O. The average duration of hospital stay was 11.2 days. The evolution was favorable in 90%. Kidney failure was the leading cause of death. Conclusion: Acute post-infectious glomerulonephritis is still a reality in our context. Emphasis should be put on its prevention by improving the hygienic conditions, detection and the management of infections.
Highlights
Acute post-infectious glomerulonephritis (APIGN) can be serious due to its complications that still occur in our countries
The clinical operational definition we adopted for APIGN was the presence of edema associated with at least another element of nephritic syndrome
Acute post-infectious glomerulonephritis occupies an important place among the infantile nephropathies [2] [3] [15] [16]
Summary
Acute post-infectious glomerulonephritis (APIGN) can be serious due to its complications that still occur in our countries. We aimed to study the epidemiological, clinical, biological and evolutionary aspects of APIGN. All children hospitalized for APIGN were included. The children spent 15.8 days before our consultation. We found a history of infection and high blood pressure in 30% each, and renal failure in 10% of the children. Conclusion: Acute post-infectious glomerulonephritis is still a reality in our context. Emphasis should be put on its prevention by improving the hygienic conditions, detection and the management of infections. APIGN is the third most frequent pathology (12.5%) behind nephrotic syndrome (43.1%) and urinary infection (22.2%) [3]. This work aimed to determine the epidemiologic, clinical, biological and evolutive characteristics of APIGN in the Malian context
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