The dual three-phase interior permanent magnet synchronous machines (IPMSMs) exhibit excellent fault-tolerant capabilities due to their multi-phase winding configurations. Under certain winding failure circumstances, by using the fault tolerant control (FTC) to reconstruct the normal rotating magnetomotive force, the machine can still provide the expected comparable torque as the healthy mode does. However, in the existing literature, limited attention was paid to the noise and vibration (NV) problems targeting the dual three-phase IPMSMs in FTC operation. To fill this knowledge gap, this paper conducts a quantitative comparison on the NV performance of a dual three-phase IPMSM under healthy and multi-phase open-circuit fault conditions under FTC. The comparative studies involve radial electromagnetic force, acceleration distribution, sound pressure level as well as machine housing deformation, which are analyzed under healthy and multi-phase open-circuit fault operations. Based on our exclusive findings, after applying the FTC, even though the machine can deliver the desired electromagnetic performance, the maximum deformation and sound pressure level of the IPMSM can be mitigated by 12.9% and 16.9%, respectively, compared to the ones under the faulty condition without FTC.