Macronutrient Distribution Research Articles

Healthy U.S.-style dietary patterns can be modified to provide increased energy from protein

BackgroundDietary patterns developed by the USDA provide modest levels of protein (14–18% energy) within the Acceptable Macronutrient Distribution Range (AMDR) of 10–35% for adults, though diets providing a higher percentage of energy may be beneficial for some individuals. The purpose of this study was to determine if it is feasible to modify the Healthy U.S.-Style Eating Pattern (“HEP”) to provide a higher percentage of energy from protein.MethodsUsing the framework implemented by the USDA in developing the HEP, energy from protein was set at 20%, 25%, and 30%. Amounts of protein foods were proportionally increased while amounts of other foods were adjusted iteratively within specified parameters. The models also disaggregated total meat/poultry into fresh and processed forms to develop patterns maintaining current proportions, current levels, reduced, or no processed meat/poultry. Nutrient intakes were compared with nutrient goals for representative U.S. populations with 2,000 kcal needs (females 19–30 years, males 51–70 years), with 90% of the Recommended Dietary Allowance or Adequate Intake regarded as sufficient.ResultsDietary patterns with 20% energy from protein were constructed with minor deviations from the current 2,000 kcal HEP. Dietary patterns with 25% energy from protein were constructed for all levels of processed meat/poultry excluding the current proportion model, though relative to the current HEP the constructed patterns reflect substantial reductions in amounts of refined grains and starchy vegetables, and substantial increases in protein foods consumed as beans and peas, seafood, and soy products. It was not possible to develop a pattern with 30% energy from protein without reducing the percentage of energy from carbohydrate below the AMDR or non-compliance with other modeling constraints. Stepwise reductions in processed meat/poultry reduced sodium intake.ConclusionsIt is feasible to develop dietary patterns in a 2,000 kcal diet while mirroring the HEP that meet recommended intakes of nutrients with 20% or 25% energy from protein, though the pattern with 25% energy from protein may be more idealistic than realistic. Reduced levels of processed meat/poultry may translate to lower sodium intake.

Food consumption patterns, socio-demographic status and nutritional risks of women in low and middle income communities in Kwandengezi, Kwazulu-Natal, South Africa

Food consumption patterns have changed dramatically in recent times. Traditional diets are replaced by “westernised diets” causing nutritional risks like malnutrition. Unemployment and lack of nutrition education have an impact on communities, in terms of the foods being purchased and consumed. This research seeks to establish a true reflection of the nutritional status, food intake patterns of the communities participating in the study and influencing factors. This is to estimate if the low income community, the north section is in a more disadvantaged situation when compared to the middle income community, the south section. The objective was to determine the socio-demographic status, food consumption patterns and nutritional risk of a low-income and middle-income community that reside in KwaNdengezi Township in KwaZulu-Natal, South Africa.The research being undertaken consists of descriptive and theoretical studies. Upon consention, participants data were collected by means of an interview setting. A set of questionnaires included, Socio-demographic, Food Frequency and 24-Hour Recall questions. The anthropometric measurements were taken in order to determine the body mass index status. Both sections of the township were affected by unemployment. The education status of the participants showed concern as both sections had fewer graduates. The mean Food Variety Scores (FVS) (±SD) for all items consumed from various food groups during seven days, indicated a medium where both sections had a good dietary diversity score ranging from 7-9 food groups, which summarize the food group diversity as being in the majority in the north section. The results of energy distribution of macronutrients from the average of the 24-hr recall when compared to the WHO dietary factor goals showed that the participants’ diet was well balanced, in relation to macronutrient intake for both sections but was lacking in micronutrient intake. Overweight and obesity tests showed disturbing results with majority of women caregivers in both sections found to be obese, showing risks of obesity related illnesses (NCDs). More nutrition knowledge should be geared towards educating the most vulnerable and poverty stricken communities. The micronutrient intake must be promoted at lower and middle income communities.. The government should devise and implement projects that empower women so that they are not co- dependent. Key words: Food, Consumption, Low and Middle- income, Education, Nutritional risks, KwaNdengezi, South Africa

Association between macronutrients intake distribution and bone mineral density

Although it is well known dietary factors are closely correlated with bone health, the association between macronutrients intake distribution and bone mineral density (BMD) is still unclear. The aims of this study were to investigate how macronutrients distribution was correlated with BMD, and to evaluate how the substitution between macronutrients could be associated with BMD. We conducted a cross-sectional study based on data from National Health and Nutrition Examination Survey. Dietary recall method was used to assessed the intake of macronutrients. Macronutrient intake distribution including carbohydrate, protein and fat was calculated as percentages of energy intake from total energy. BMD was converted to T-score and low BMD was defined as T-score less than-1.0. The association between the percentages of energy intake from carbohydrate, protein and fat with T-score and risk of low BMD was evaluated using multivariate regression models. Isocaloric substitution analysis was conducted using the multivariate nutrient density method. Data form 4447 adults aged 20 years and older who underwent BMD examination were included in this study. Higher percentage of energy intake from carbohydrate was associated with lower T-score (-0.03 [95%CI,-0.05 to-0.01]; P=0.001) and higher risk of low BMD (1.05 [95%CI, 1.02-1.08]; P=0.003), while higher percentage of energy intake from protein was associated with higher T-score (0.05 [95%CI, 0.01-0.08]; P=0.009) and lower odds of low BMD (0.92 [95%CI, 0.87-0.98]; P=0.007). The percentage of energy intake from fat seemed to be positively correlated with T-score, but the correlation became insignificant after adjusting for metabolism related confounders. Isocaloric substitution analysis showed that only the substitution between carbohydrate and protein was significantly and independently associated with T-score (-0.05 [95%CI,-0.08 to-0.01]; P=0.01) and the risk of low BMD (1.08 [95%CI, 1.02-1.15]; P=0.008). Based on the results from this study, we hypothesized that a high-protein diet coupled with low carbohydrate intake would be beneficiary for prevention of bone loss in adults. However, randomized clinical trials or longitudinal studies are needed to further assessed our findings.

Food consumption patterns and nutrient intakes of infants and young children amidst the nutrition transition: the case of Lebanon

BackgroundThis is the first study on dietary intakes of infants and young children in the Eastern Mediterranean Region, a region that is currently witnessing the nutrition transition. It aims at characterizing food consumption patterns amongst 0–4 year old children in Lebanon, evaluating their macro- and micronutrient intakes and assessing adherence to dietary recommendations.MethodsBased on a national cross-sectional survey in 2012 (n = 866), the study collected data on sociodemographic and anthropometric characteristics, and one 24-hour dietary recall was administered. Nutrient intakes were compared with reference values: Estimated Average Requirement (EAR), Adequate Intake (AI) and Acceptable Macronutrient Distribution Range (AMDR).ResultsMilk was the highest contributor to energy intake (EI) in infants (95.8 and 56.5% in 0–5.9 months and 6–11.9 months old infants, respectively), while its intake was lower among toddlers and preschoolers (35.4 and 15.1%, respectively). In contrast, intakes of sweets and sweetened beverages were the highest in preschoolers compared to younger children, contributing 18.5% EI in preschoolers. Compared to dietary guidelines, the lowest dietary adherence was found for vegetables (17.8–20.7%) and fruits (14.4–34.3%). Protein intake was within the recommendations for the vast majority of children. Although total fat intake was lower in toddlers and preschoolers compared to infants, more than 40% of toddlers and preschoolers exceeded the AMDR for fat and 87.3% of preschoolers exceeded the upper limit for saturated fat. Only 3.6% of toddlers and 11.5% of preschoolers exceeded the AI level for dietary fiber. Micronutrient intake assessment showed that mean intakes in infants exceeded the AI for all micronutrients, except for vitamin D and magnesium. In toddlers, vitamin D and calcium were below the EAR among 84.7, and 44.6%, respectively. In preschoolers, most of the children (91.9%) had inadequate intakes of vitamin D, and a third had inadequate intakes of folate, calcium and vitamin A.ConclusionsThis study identified priority issues for nutrition intervention in infants and young children in Lebanon. Concerted multi-stakeholder efforts are needed to instill heathier food consumption and nutrient intake patterns early in life.

Weight-loss induced by carbohydrate restriction does not negatively affect health-related quality of life and cognition in people with type 2 diabetes: A randomised controlled trial

We evaluated the effect of weight loss induced by dietary carbohydrate restriction on health-related quality of life (HRQoL) and cognition in type 2 diabetes (T2D). In this randomised parallel trial, 72 adults with T2D and overweight/obesity (mean±SD, HbA1c: 57±8mmol/mol and BMI: 33±5kg/m2) were randomly assigned to a carbohydrate-reduced high-protein diet (CRHP: C30E%-P30E%-F40E%) or conventional diabetes diet (CD: C50E%-P17E%-F33E%) for 6 weeks, targeting a 6% weight loss. HRQoL was assessed from the short form 36 (SF-36) questionnaire, including physical and mental component summary (PCS and MCS) scores; global cognition, verbal memory, attention and psychomotor speed, and executive function were assessed from a neuropsychological test battery. Both diet groups achieved a 5.8kg weight loss and improved PCS (median [25th;75th percentiles], CD: 2.7 [1.1; 4.2] vs. CRHP: 2.1 [0.7; 3.7]), with no difference between diets. The CRHP diet resulted in a clinically relevant improvement of MCS, albeit non-significantly different compared with the change after the CD diet (2.0 [-0.7; 4.8], p=0.15). Global cognition, attention, and verbal memory were unaffected by the CRHP diet, which selectively worsened the Symbol Digit Modality Test assessing psychomotor speed when compared with the CD diet (-4.1 [-7.2;-1.1], p<0.01). Physical health improved by weight loss independently of macronutrient distribution, while mental health and cognition may be affected by the amount of carbohydrate, protein and fat in the diet. Collectively, our data suggest that weight loss through moderate carbohydrate restriction has no clinically important impact on HRQoL and global cognition in patients with T2D. Registered under ClinicalTrials.gov Identifier no. NCT03814694.

Correlation between Sarcopenia Risk and Food Intake in Older Hospitalized Unselected Cancer Patients

Objectives: Recently, the SARC-F (Strength, Assistance for walking, Rise from a chair, Climb stairs, and Falls) questionnaire was developed to screen for the risk of sarcopenia in older patients. However, no study has investigated whether SARC-F is linked to food intake. This study aimed to evaluate the relationship between SARC-F and food intake in older hospitalized unselected cancer patients. Methods: A cross-sectional study included 53 older hospitalized unselected cancer patients. The SARC-F score was used to identify muscle function loss (SARC-F ≥ 4) or sarcopenia risk [SARC-F + calf circumference (CC) ≥ 11]. Pearson’s correlation was used to assess the relationship between SARC-F and food intake. Results: We found that 51% of patients presented with SARC-F ≥ 4 and 56.6% with SARC-F + CC ≥ 11. Although these patients had a lower calorie intake (22.4 ± 11.9 kcal/kg/day), they had an adequate distribution of macronutrients. We found a negative correlation between the SARC-F score and the calorie and macronutrient intake. However, SARC-F + CC was not correlated with calories and carbohydrates, only with lipid and protein intake. Conclusions: Approximately half of unselected cancer patients presented with muscle function loss (SARC-F ≥ 4) or sarcopenia risk (SARC-F + CC ≥ 11). In addition, we showed an inverse weak correlation between SARC-F and food intake, but not between SARC-F + CC and calories and carbohydrates, suggesting that the SARC-F questionnaire may be used with caution to screen for muscle function loss and correlation with food consumption.

A Descriptive Analysis of Macronutrient, Fatty Acid Profile, and Some Immunomodulatory Nutrients in Standard and Disease-Specific Enteral Formulae in Europe.

Foods for special medical purposes (FSMPs) are commercially available formulations used as a source of nutrition when administered orally or by tube feeding. This study examines, for the first time, the nutritional composition of enteral formulae (EFs) according to European nutritional guidelines. We developed a descriptive study on 118 EFs from 2020 to 2021. Formulae were classified as standard (SFs) and disease-specific (DSF). According to the protein-energy content, SFs were classified into G1, normoprotein-normocaloric; G2, normoprotein-hypercaloric; G3, hyperproteic-normocaloric; and G4, hyperproteic-hypercaloric. Disease-related formulae for metabolic stress, renal, cancer, pulmonary, diabetes, malabsorption, and surgery were studied. Macronutrient distribution, fatty acid profile (monounsaturated [MUFA], polyunsaturated [PUFA], saturated [SFA]), derived fat quality indexes, and immuno-modulatory nutrients (omega-3, eicosapentaenoic acid [EPA], docosahexaenoic acid [DHA], arginine and nucleotides) per 1,500 kcal infused were calculated. In total, 53% were SFs, mainly normoproteic (G1, G2) with higher carbohydrate contents in normocaloric vs. hypercaloric SFs. The most balanced fatty acid profiles (MUFA: 17.7%; PUFA: 6.8%; SFA: 9.5%) belonged to G1. The PUFA/MUFA ratio: ≥0.5 was in 85.7% with a higher proportion of EPA+DHA (46%) vs. omega-3 (15.8%) in SFs. In DSFs (46.9%), higher carbohydrate content (>50%) was in malabsorption and surgery, whereas high-fat content (>50%) was in pulmonary and renal formulae. DSFs had higher SFA vs. MUFA content, except for diabetes. EPA and DHA were added in 45.5% (cancer, malabsorption, and surgery). Only 12.7% of DSFs had arginine and nucleotides. A higher proportion of SFs was found, in line with current European guidelines. Results highlighted a wide intra-group variability of nutrients among the formula selected. These findings are useful to evaluate the nutritional composition of EFs from a preventive and/or therapeutic perspective in clinical settings.

Food and nutrient intake of school-aged children in Lebanon and their adherence to dietary guidelines and recommendations

BackgroundLebanon, an Eastern Mediterranean country, is witnessing a remarkable nutrition transition, and the diets of school-aged children may be amongst those most affected. However, limited studies have examined the food consumption patterns and nutrient adequacy in this age group.ObjectivesThe present study aimed to evaluate the dietary intakes of school-aged children in Lebanon and assess their adherence to nutrition guidelines and recommendations.MethodsThis study used data for 4–13 y-old children (n = 711) from a national cross-sectional survey conducted in 2014–2015 on a representative sample of Lebanese households with children. Dietary intake was assessed using single 24-h recall method. Estimated food group and nutrient intakes were compared to dietary recommendations and age-specific dietary reference intakes (DRI), including Estimated Average Requirements (EAR) and Acceptable Macronutrient Distribution Range (AMDR). Food group, energy, macro- and micro-nutrient intakes were presented for all children in the sample and stratified by age (4–8 y and 9–13 y) and sex.ResultsMean energy intake of 4–13-year-old children was 1804 kcal/d. Almost half of the energy was provided by carbohydrates while 12% of children had protein intakes below EAR. Approximately three-quarters of children (4–13 y) exceeded the AMDR for total fat and saturated fats, and a similar proportion over consumed added sugars. The main sources of energy intake (EI) among children were the sweets, sweetened beverages and desserts followed by grains and mixed dishes. No significant differences were noted in %EI from different food groups, by sex, in either age groups. The highest adherence of children to food group recommendations was observed for the grains’ food group (47.2–54.4%EI), while the lowest adherence was found for vegetables (3.1–14.1%EI). A high prevalence of vitamin and mineral inadequacies was noted amongst 4–13 y old children for key micronutrients, including vitamin D (99%), calcium (81%), and vitamin A (69.5%). Risk of inadequate micronutrient intakes was significantly increased among the older age group (p-value < 0.05).ConclusionNutrient intakes of school-aged children in Lebanon reflect suboptimal nutrition. Educational and public health interventions are needed to promote healthier diets among children and prevent micronutrient deficiencies during this critical phase.

The Effect of Protein Supplementation During Time Restricted Feeding in Overweight and Obese Adults

ObjectiveObesity in the United States continues to increase. Time restricted feeding (TRF) is a dietary intervention that has potential to serve as an effective weight loss strategy, however more data is needed to establish the effectiveness of a TRF eating pattern on health outcomes related to obesity. To our knowledge, manipulation of macronutrient distribution during a TRF intervention and the effect of TRF on sleep and mood have not been studied. Therefore, the objective of this study was to determine the effect of protein supplementation during TRF on mood, sleep, and appetite in overweight and obese adults.MethodsOverweight and obese men and women (36.6±7.3 years; BMI: 32.8±6.5) participated in this randomized, controlled 12‐week dietary intervention. Participants were allocated to one of two groups: 1) control, TRF (n=7) and 2) TRF with whey protein supplementation (25 g/d; n=9). Protein supplements were consumed at the breaking of the fasting period each day. Anthropometrics, sleep (via Pittsburgh Sleep Quality Index Global Sleeping Score; PSQI GSS), total mood disturbances (TMD; via Profile of Mood States (POMS) including six affect states of depression, fatigue, anger, tension, confusion, and vigor subscales), and appetite (using visual analog scales) were assessed at 0, 4, 8, and 12 weeks. Sleep was also measured at 0 and 12 weeks via wrist Actigraphy. Body composition was measured via DXA at 0 and 12 weeks. Data was analyzed using two‐way ANOVA to assess the relationship.ResultsOverall, both interventions improved total body fat percentage (p&lt;0.05) over 12 weeks. There was a significant difference in mood between intervention groups (p&lt;0.001) and the control group total mood disturbance was significantly different (p&lt;0.05) between week 1 and 12. However, there was no change in mood with protein supplementation over the span of 12 weeks. Sleep, self‐reported via PSQI, did not change from week 1 and week 12 within or between each of the interventions. Appetite did not show a significant difference between interventions or time points.ConclusionsThis pilot study suggests that protein supplementation during TRF has the potential to improve body composition in overweight and obese individuals. However, additional research is needed to determine the long‐term effect of protein supplementation in combination with TRF on mood, sleep, and appetite.

Meal timing, distribution of macronutrients, and inflammation among African-American women: A cross-sectional study

ABSTRACT Chronic low-grade inflammation is an underlying risk factor for numerous chronic diseases, including cancer. Eating earlier in the day has been associated with a reduction in levels of inflammatory markers and inflammation-related health outcomes (e.g., obesity, metabolic disorders). This cross-sectional study of 249 obese African-American women examined the effect of various mealtime-related factors associated with macronutrient consumption in relation to chronic inflammation and Breast Imaging Reporting and Data System (BI-RAD) readings. During 2011 and 2013, a single 24-hour dietary recall was administered, blood samples were assayed for c-reactive protein (CRP) and interleukin-6 (IL-6), and BI-RAD ratings were assessed to determine the influence of mealtime on chronic inflammation and breast cancer risk score. Multiple linear and logistic regression models were used to assess these relationships. Higher carbohydrate consumption at breakfast was associated with a significantly lower CRP vs. higher carbohydrate consumption at dinner (6.99, vs. 9.56 mg/L, respectively, p = .03). Additionally, every 1-unit increase in percent energy consumed after 5PM resulted in a BI-RAD reading indicating a possibly suspicious abnormality (OR: 1.053, 95% CI: 1.003–1.105), suggesting an increase in breast cancer risk. Timing of energy and macronutrient intake may have important implications for reducing the risk of diseases associated with chronic inflammation.

Analysis of the distribution of macronutrients of food baskets delivered by municipalities during the COVID-19 pandemic in Peru.

To evaluate and compare the macronutrient distribution of the food baskets delivered by Peruvian municipalities during the COVID-19 pandemic according to the geographic domain and assigned budget level. Secondary analysis of the database "Consultation of Acquisition and distribution of basic necessities of the basic family basket" of the General Comptroller of the Republic. Stratified probability sampling was carried out. The caloric intake distribution was calculated according to macronutrients and compared with the Acceptable Intervals of Macronutrient Distribution (IADM) of the Nutrition Institute of Central America and Panama (INCAP) and the National Institute of Civil Defense (INDECI). At the national level, the median caloric intake of proteins was 7.7%; for carbohydrates it was 62.5%; and for fats it was 28.1%. The proportion of municipalities with protein deficit was 84%; Municipalities with excess carbohydrates ranged from 16.5% (according to INCAP) to 35.9% (according to INDECI), and with excess fat, it was between 61.6% (according to INCAP) and 20.2% (according to INDECI). According to INDECI, nationally only 9.2% of municipalities delivered baskets with an adequate distribution of macronutrients; Metropolitan Lima stands out with the highest proportions of adequate baskets, while in the Jungle region this percentage was less than 5%. Most of the baskets delivered did not have adequate macronutrient distribution. Especially the baskets of municipalities outside of Metropolitan Lima or those that had smaller budget. Carbohydrates and fats were the nutrients that were included in excess, while proteins were deficient.

Effect of gravity-fed drip irrigation and nitrogen management on flowering quality, yield, water and nutrient dynamics of gladiolus in an Indian inceptisol

Gladiolus is a promising flower crop during winter season and its popularity is growing fast due to its higher price in the market. However, the productivity and quality of the crop in resource-scarce region are constrained by improper irrigation and nitrogen management practices. Based on this presumption, the current study has been developed with the precise objectives of examining the effect of gravity-fed drip irrigation scheduling coupled with integrated nitrogen management on growth, yield, water productivity and macronutrients distribution in soil and plant system of gladiolus. The field experiment accommodating four irrigation levels (surface irrigation I1, and gravity drip irrigation at 1.0, 0.8 and 0.6 (I2, I3 and I4) of pan evaporation replenishment) and three levels of nitrogen management (100% recommended dose of nitrogen (RDN) as vermicompost, 50% RDN as vermicompost + 50% RDN as fertilizer and 100% RDN as fertilizer, respectively N1, N2 and N3) was conducted during three consecutive rabi seasons on gladiolus. I2N2 furnished highest spike/plot (72.9), florets/spike (10.6), longest spike length (66.7 cm), greatest spike weight (43.0 g) and maximum spike yield (10458 kg ha−1) which were at par with I2N2. Highest crop water productivity (CWP) of 9.06 kg m−3 was accomplished in I4N2 followed by I3N2 (8.84 kg m−3). Drip irrigation, on average, could save water by 20.6% for I2, 36.6% for I3 and 52.4% for I4 and improve CWP by 50.2% for I2, 65.2% for I3 and 65.2% for I4 as compared with I1. Two predictive models were developed based on flower yield vs. I and ETa. Ky for total growing season was estimated at 0.66 (R2= 0.91). Maximum soil water storage was accumulated in the surface layer and well distributed down the layers underneath in drip irrigation system, while the reverse trend was noticed in the surface irrigation. Higher availability of soil N and leaf N concentrations were obtained with I2N2 and I3N2 and lower with I1N1. Based on maximum spike yield, water productivity, substantial water saving and N economy, I2N2 and I3N2 emerged superior for the selected inceptisol.

Near-Infrared Spectroscopy and Mode Cloning (NIR-MC) for In-Situ Analysis of Crude Protein in Bamboo

This study develops Near-Infrared Spectroscopy (NIRS) and Mode-Cloning (MC) for the rapid assessment of the nutritional quality of bamboo leaves, the primary diet of giant pandas (Ailuropoda melanoleuca) and red pandas (Ailurus fulgens). To test the NIR-MC approach, we evaluated three species of bamboo (Phyllostachys bissetii, Phyllostachys rubromarginata, Phyllostachys aureosulcata). Mode-Cloning incorporated a Slope and Bias Correction (SBC) transform to crude protein prediction models built with NIR spectra taken from Fine–Ground leaves (master mode). The modified models were then applied to spectra from leaves in the satellite minimal processing modes (Course–Ground, Dry–Whole, and Fresh–Whole). The NIR-MC using the SBC yielded a residual prediction deviation (RPD) = 2.73 and 1.84 for Course–Ground and Dry–Whole sample modes, respectively, indicating a good quantitative prediction of crude protein for minimally processed samples that could be easily acquired under field conditions using a portable drier and grinder. The NIR-MC approach also improved the model of crude protein for spectra collected from Fresh–Whole bamboo leaves in the field. Thus, NIR-MC has the potential to provide a real-time prediction of the macronutrient distribution in bamboo in situ, which affects the foraging behavior and dispersion of giant and red pandas in their natural habitats.

The Effect of Dietary Interventions on Hypertriglyceridemia: From Public Health to Molecular Nutrition Evidence.

Approximately 25–50% of the population worldwide exhibits serum triglycerides (TG) (≥150 mg/dL) which are associated with an increased level of highly atherogenic remnant-like particles, non-alcoholic fatty liver disease, and pancreatitis risk. High serum TG levels could be related to cardiovascular disease, which is the most prevalent cause of mortality in Western countries. The etiology of hypertriglyceridemia (HTG) is multifactorial and can be classified as primary and secondary causes. Among the primary causes are genetic disorders. On the other hand, secondary causes of HTG comprise lifestyle factors, medical conditions, and drugs. Among lifestyle changes, adequate diets and nutrition are the initial steps to treat and prevent serum lipid alterations. Dietary intervention for HTG is recommended in order to modify the amount of macronutrients. Macronutrient distribution changes such as fat or protein, low-carbohydrate diets, and caloric restriction seem to be effective strategies in reducing TG levels. Particularly, the Mediterranean diet is the dietary pattern with the most consistent evidence for efficacy in HTG while the use of omega-3 supplements consumption is the dietary component with the highest number of randomized clinical trials (RCT) carried out with effective results on reducing TG. The aim of this review was to provide a better comprehension between human nutrition and lipid metabolism.

Going Conservative or Conventional? Investigating Farm Management Strategies in between Economic and Environmental Sustainability in Southern Italy

The European “Green Deal” strategy is aimed at making Europe the first climate-neutral continent by 2050 through integrated actions relying on healthier agricultural systems grounded in (environmental and economic) sustainable practices, including soil carbon management and biodiversity enhancement. In this vein, the present study contrasts the economic-environmental performances of conventional (deep tillage) and conservative (no-tillage and soil ripping) practices for two varieties of durum wheat (Triticum turgidum spp. durum), namely a modern (Anco Marzio) and an ancient landrace (Saragolla Lucana) variety in the Basilicata region (Southern Italy). Field and laboratory analysis (granulometry, mineralogy, and geochemistry) as well as satellite data (RapidEye) were used to characterize the soil and vegetation patterns. The empirical results indicate a higher biomass production and vegetative potential together with higher grain yields in soils managed with conventional deep tillage compared with soil managed with conservative practices. Similarly, the modern wheat variety exhibited better performance with respect to the old landrace. The soils managed with conventional practices had a distribution of exchangeable macro-nutrients characterized by a reduction in Ca+ and an increase in Mg2+ and K+ between pre-sowing and post-harvesting. Such a distribution was also genotype-dependent, with a higher variability for Saragolla Lucana than Anco Marzio, showing a diverging adsorption of macro-elements between the modern and ancient landrace varieties.

Formulation of Local Food Based Snack Using Linear Program for Nutrisurvey to Prevent Stunting in Under-Five Children

The prevalence of stunting in Indonesia has decreased from 37.2% in 2013 to 30.8% in 2018. This prevalence is still far from the government target, which is 14%. Immunostimulant prebiotic food formulations in the form of snack bars made from lempeni leaves, edamame, and local herbal plants can be used to increase immunity and prevent stunting among children. However, the development of a local-based diet by considering the nutrient adequacy of the children is lacking. This study aimed to develop an optimized snack bar based on nutrient adequacy using linear programming to meet the nutrient requirement of under-five children. This study used Nutri Survey for Linear Programming 2004 software to develop an optimized snack bar. Nutrition Adequacy Rate among children 1-4 years were used to determine the composition of the snack bar. The composition of the snack bar consists of Simplicia powder of lempeni leaves, edamame, cinnamon powder, ginger powder, oats, almonds, cashew, raisins, honey, peanut butter, and chocolate. The Results show two formulas based on Linear Programming calculation and one formula for control. Snack bar formula fulfilled energy and macronutrient intake requirements within the acceptable macronutrient distribution range. Formula 1 contains 122 kcal energy; 2,9 g protein; 4,9 g fat; 13,4 g carbohydrate, 0,8 mg iron; and 0,4 mg zinc. Formula 2 contains 123 kcal energy; 3,05 g protein; 5,6 g fat; 13,5 g carbohydrate, 0,9 mg iron; and 0,4 mg zinc. Those values are describe the optimization model used in this study provides a mathematical solution for an economical snack bar that approximate the nutrient requirements for under-five children to prevent stunting.

Innovative Nutrition Education: A Color-Coded Tool for Individuals with Low Literacy Level.

(1) Background: The food exchange system was developed to serve as an educational tool in helping individuals plan their own meals. This study aimed to develop a friendly-user food exchange list for individuals with a low literacy level; (2) Methods: A two-group, pre-test/post-test research study aimed to develop a friendly-user food exchange list for individuals with a low literacy level. Thirty female workers of low literacy were recruited. Participants were divided into two groups. Group one was taught how to use the standard exchange system, while group two was taught how to use the modified exchange system. Each participant was assigned a task of prepare a meal with a specified caloric content and macronutrient distribution. The task was assigned before and after the exchange list education session. Groups’ differences were tested using the chi-square test, and the analysis of variance (ANOVA); (3) Results: A higher percentage of participants in group two were able to plan daily diets that achieved the recommendations of fruits (p = 0.02), protein (p = 0.03), dairy (p < 0.001), carbohydrates (p < 0.001), and calories (p < 0.001). Moreover, diet plans prepared by group two had a higher healthy eating index (p < 0.001) when compared to diet plans prepared by group one. The modified exchange lists are a friendly-user tool that can be implemented for individuals with low literacy, since it relies on visual techniques.

Effects of Dietary Fat to Carbohydrate Ratio on Obesity Risk Depending on Genotypes of Circadian Genes.

Although the impacts of macronutrients and the circadian clock on obesity have been reported, the interactions between macronutrient distribution and circadian genes are unclear. The aim of this study was to explore macronutrient intake patterns in the Korean population and associations between the patterns and circadian gene variants and obesity. After applying the criteria, 5343 subjects (51.6% male, mean age 49.4 ± 7.3 years) from the Korean Genome and Epidemiology Study data and nine variants in seven circadian genes were analyzed. We defined macronutrient intake patterns by tertiles of the fat to carbohydrate ratio (FC). The very low FC (VLFC) was associated with a higher risk of obesity than the optimal FC (OFC). After stratification by the genotypes of nine variants, the obesity risk according to the patterns differed by the variants. In the female VLFC, the major homozygous allele of CLOCK rs11932595 and CRY1 rs3741892 had a higher abdominal obesity risk than those in the OFC. The GG genotype of PER2 rs2304672 in the VLFC showed greater risks for obesity and abdominal obesity. In conclusion, these findings suggest that macronutrient intake patterns were associated with obesity susceptibility, and the associations were different depending on the circadian clock genotypes of the CLOCK, PER2, and CRY1 loci.

Nutrient Intakes among Brazilian Children Need Improvement and Show Differences by Region and Socioeconomic Level.

Brazil is the most populous country in South America. Using 24 h dietary data, we compared the nutrient intakes of 4–13-year-olds to reference values and tested for regional and socioeconomic (SES) differences. A considerable proportion reported intakes below the Estimated Average Requirements (EAR) for vitamins E (78.1%, 96.5%), D (100% for both), and calcium (80.5%, 97.7%) for 4–8 and 9–13-year-olds, respectively. Few exceeded Adequate Intakes (AI) for potassium or fiber. Older children reported greater inadequacies and, while there was regional variability, patterns of inadequacy and excess tended to be similar. For vitamin C, the percent of children below EAR in the Northeast and Southeast was lower than in the South. Most children, regardless of SES, had energy intakes within the Acceptable Macronutrient Distribution Ranges (AMDRs) for carbohydrates and protein. Over a quarter reported total energy from fat less than the AMDR, and inversely associated with SES (low 50.9%, moderate 26.0%, and high 15.0%), but also exceeding the percentage of energy recommendation for saturated fat, increasing with SES (low 18.1%, moderate 38.9%, and high 48.8%). The contrast observed between the diets of young Brazilians and recommendations underscores the need for individual and regional environmental interventions to promote healthier dietary patterns.

P391 Unpacking the different popular diets for pediatric Crohn’s disease - concerns around nutritional adequacy

Abstract Background The first line treatment for inducing remission in pediatric Crohn’s disease (CD) is Exclusive Enteral Nutrition (EEN), where a patient drinks a nutritionally complete formula exclusively for, 6 to, 12 weeks. Despite the effectiveness of EEN, some patients may experience challenges including taste fatigue, monotony, and a lack of social participation with meals. Given these challenges, patients may turn to popular or fad diets for managing their disease. These diets are often restrictive, eliminating a number of foods and exacerbating the risk of underlying nutrient deficiencies in this patient population. Methods These case studies involved a nutrient analysis of evidence-based and popular diets for CD, including Crohn’s Disease Exclusion Diet (CDED), CD-TREAT, Specific Carbohydrate Diet (SCD), IBD Anti-inflammatory Diet (IBD-AID), Autoimmune Protocol (AIP) Diet, Gut and Psychology Syndrome (GAPS) Diet, and low FODMAP. Four cases were selected with mild-moderate CD:, 11-year-old and, 16-year-old, both male and female. A nutrient analysis of sample menus of each diet was completed using Food Processor version of, 11.6.0 by ESHA Research. Results were compared to age and gender specific Dietary Reference Intakes (DRIs), population-based dietary intake data, and Health Canada Dietary Guidelines. Results Data are presented for Case, 1, 11-year-old male. Findings were comparable to other age and gender cases. As compared to Acceptable Macronutrient Distribution Ranges (AMDRs), there was a higher percentage of energy from fats and lower from carbohydrates for the SCD (% kcal, fat and carbohydrate respectively:, 59%;, 30%), IBD-AID (52%;, 37%), AIP Diet (50%;, 20%) and GAPS Diet (60%, 21%). Saturated fat intake exceeded recommendations (&amp;gt;10% of energy intake) for CDED (% kcal, 14%) CD Treat (17%), SCD (11%), AIP Diet (15%) and GAPS Diet (20%). Both vitamin D and/or calcium intake were below the Recommended Dietary Allowance (RDA) respectively for CDED (% RDA, vitamin D and calcium respectively:, 89%;, 86%), SCD (23%;, 53%), AIP Diet (14%;, 23%), low FODMAP Diet (4%, 96%) and GAPS Diet (calcium, 58%). Adolescent females versus males between the ages of, 14–18 years may be at greater risk of inadequate nutrient intake, given the general increase in nutrient requirements yet lower caloric needs. Conclusion Given the increase in awareness and interest in popular diets for Crohn’s disease, it is imperative that clinicians are aware of the risks of inadequate nutrient intake with restrictive diets.