This work aims to address the technical issue of continuously decreasing reheat temperature in the S-CO2 coal-fired power system under partial-load operation. A novel partial flow arrangement of heating surfaces that uses part of the cooling walls in the furnace chamber as reheating surfaces was proposed. The steady-state model of a 300 MW S-CO2 coal-fired power system was developed to predict the partial-load operating characteristics. It is found that the proposed partial flow arrangement can effectively alleviate reheat temperature deviation. For the deviation of 10 °C, the present boiler operating load can be reduced to as low as 40% whereas at least an 80% load ratio for the traditional arrangement. According to the effects of four regulation measures, the comprehensive control sequence is suggested as 1) flue gas damper angle, 2) split ratio of the stream to FGC, 3) burner angle, and 4) split ratio of the stream to recompressor. This strategy can stabilize the reheat temperature at 620 °C for the load ratio decreasing from 100% to 37%, and achieve the higher system thermal efficiency. For load ratios from 37% to 20%, the reheat temperature cannot remain stable, and adjusting the reheat temperature will decrease the thermal efficiency.