With massive and dense production, the livestock industry is rapidly moving into a large-scale, capital-intensive industry especially in swine, poultry, and ducks. However, livestock epidemics can pose a serious threat to the livestock industry and the lives of the people. The government has established and operates the National Animal Protection and Prevention System (KAHIS) since 2013 in order to control the threat, in accordance with the five stages. The digitalized data and information are excellent in ease of management, but it is also pointed out that it is difficult to take countermeasures through linkage with the data in an emergency situation. Recently, the technology of the fourth industrial revolution such as Internet of Things (IoT), Big Data, Artificial intelligence (AI) has been rapidly implemented to the livestock industry, which makes smart livestock disease control system possible. Therefore, this study investigated the domestic and overseas cases which apply 4th Industrial Revolution technology in the industry, and derived 13 possible candidate tasks in the near future. In order to ascertain the priority of policy formulation, we surveyed the expert groups and examined the priority of each of the five stages of the prevention and the priority of each stage. The results of this study are expected to contribute to the establishment of policies for the advancement of smart livestock disease control research and livestock protection.