The article presents the results of an empirical study of the level of stress resistance and coping strategies in first-year medical residents in surgical and pediatric specialties. The problem of adaptation of a young specialist during the period of training in residency to medical practice is relevant, since during this period the correctness of the chosen medical specialty and the career path of a specialist are assessed. As a result of our study, data were obtained on a high level of stress and low adaptation in the residents. Among surgical residents, stress levels are significantly higher. Preferred coping strategies among surgical residents are decision-making and positive reappraisal. Pediatric residents have predominance of escape-avoidance and decision-making coping strategies. The obtained data on the psychological status of medical residents at the initial stage of their career path enabled us to develop a program of psychological support, including diagnosis and training aimed at reducing stress and developing effective behavioral strategies.