The flock was prepared on the basis of a report made at the scientific and practical conference «Organization of deratization measures in modern conditions, topical issues of disinfection activities in the conditions of medical organizations of various profiles,» held May 15–16, 2024 in St. Petersburg. The interaction between the medical and non-medical units of the hospital, their well-coordinated work is one of the most important factors in the provision of high-quality medical care in a large multidisciplinary hospital. The implementation of preventive and anti-epidemic activities is often distributed among departments, and non-medical specialists do not always understand the need for these measures. To improve the quality of medical care and improve the interaction between services, a new department was introduced into the staff of a large multidisciplinary hospital – the department of preventive disinfection. Keywords: multidisciplinary hospital, preventive disinfection department, linen regime, disinfectants, disinfection, deratization, medical waste management, disinfection chamber, preventive activities, anti-epidemic measures, interaction between medical and non-medical units.