Heat transfer in partially ionized Erying-Powell liquid containing four types of nano-particles is discussed in this manuscript. Mathematical models for the mixture Erying-Powell plasma and nano-particles are developed and are solved by using finite element method (FEM). Numerical computations are carried out under tolerance 10-5. Physical parameters have significant effects on both thermal boundary layer thicknesses and momentum boundary layer thicknesses. Shear stresses at the surface can be minimized by the Hall and ion slip currents whereas the shear stresses at the sheet for Erying-Powell fluid are high as comparing to the Newtonian fluid. The rate of transfer of heat is significantly influenced by Hall and ion slip parameters. Highest rate of transfer of heat is observed for the case of TiO2 nano-particles. Therefore, it is recommended to disperse TiO2 nano-particles in Erying-Powell fluid for enhancement of heat transfer in Erying-Powell plasma.