s / Photodiagnosis and Photodynamic Therapy 12 (2015) 325–375 367 Photodynamic field control of malaria vector, schistosomiasis and agricultural pests Mahmoud H. Abdel Kader The German University in Cairo, Egypt In this work, we present the successful field implementation of using the photodynamicmodality to control vector-borne diseases, suchasMalaria, Filaria,Dengue feverandSchistosomiasis, aswell as agro-insects which cause considerable damage to agro-economics. Field trials were performed in infested epidemic swamps in Uganda, Ethiopia and Sudan using chlorophyll derivatives as a photosensitizer which was approved by the FDA as food additives. It was added to the infested swamps to be uptaken by the mosquito larvae. The accumulated chlorophyll derivatives inside the larvae body induce, upon sunlight exposure, oxidative stress, which interrupts the life cycle of theparasite and results in organismdeath. The results revealed85–100%mortality of larvaepopulationat different concentrations of chlorophyll derivatives. The formulated photosensitizerusedachieved target selectivitywhereall otherbiological beneficiary organisms (which were present in the same treated swamps) were not affected. Using the same technique for the snail vector control (intermediate host of Schistosomiasis (Biomphalaria alexandrina), mortality percentage obtained ranges from 80% to 90%. In case of agro-insects, two different types of nano-materials (Graphene-oxide and Silver nanoparticles were conjugated with Magnesium and Copper Chlorophyllin derivatives which are used as photo-insecticide against white-fly, Cotton Worm and fruit-fly. Field results revealed that all nanocomposites achieved high reduction percentages in insects’ population ranging from 75% to 96.5%. The results reveals that this innovative modality against vector borne diseases as well as agro-pests combines both effectiveness and efficiency with the highest levels. http://dx.doi.org/10.1016/j.pdpdt.2015.07.163 Physiology properties as predictors of PDT response: Where we stand and where we are going