Ukraine carries out a wide range of measures that create the necessary conditions for work and life, improvement of the external, including industrial, environment, further development of health care. At the same time, human activity by means of physical culture and sports are important factors in improving and strengthening health, which ultimately increases a person's creative activity, his ability to work. Aim of the research - to determine experimentally the effectiveness of the application of aerobics on the psychophysiological state and the special ability of women of the teaching staff. The following research methods were used to achieve the goal: analysis, generalization, systematization of literature sources on the problem of research, questionnaires, surveys, psychophysiological research methods, pedagogical research methods. Results of the research: exercise in classical aerobics contributes to the activation of various structures of the CNS, as a result of which women began to respond more quickly to light signals. Special working capacity increased by 48.5%. Having completed the study of strength aerobics classes in women, there was a significant increase in the potential of cardiohemodynamics. Training complexes of physical exercises in aerobics with the use of various equipment, lead to the activation of different parts of the cerebral cortex, which is expressed in a reduction (approximately 15%) of the visual-motor reaction time, increases (approximately 14.5%) special performance. Under the influence of training on strength training equipment in women, the potential of cardiohemodynamics decreases, and on the other hand, as a result of activation of the cortical structures of the brain, professional efficiency increases. Conclusions. Systematic physical culture and sports normalize the work of almost all organs and systems of the body, increase the psycho-emotional state, physical and mental activity.