By the year 2020, 90% of the population with access to electricity worldwide was surpassed. However, the reality is very different for many countries, especially for those on the African continent that had more than 572 million people without electricity service at the end of 2019. This work studies the implementation of an isolated microgrid activated with photovoltaic energy and energy storage in batteries under the case study of the community of Bigene, located in the African country of Guinea-Bissau. This type of project is a potential solution to the problem of access to energy, but as the cost of the energy storage system is typically very high, this work technically and economically addresses the effect of using absorbed glass material (AGM) and lithium batteries. A simulator was developed using TRNSYS software to analyze the operation of the microgrid under a defined annual demand profile for different types of users, and economic analysis was conducted considering a project lifetime of 25 years. The results showed no significant differences in the solar fraction of both types of batteries when the photovoltaic power was less than 600 kW, regardless of the capacity of the storage bank. The analysis of auxiliary power requirements showed that lithium technology leads to a lower consumption from 800 kW of PV capacity, and utilizing less than this capacity did not have a significant difference with AGM batteries. In this microgrid with a photovoltaic capacity of less than 700 kW and an energy storage of less than 2580 kWh, the type of storage technology, AGM or lithium, did not represent a considerable difference in the levelized cost of energy, indicating that AGM technology could be selected considering its low initial investment cost compared to lithium batteries.