Incorporating slip conditions into computational fluid dynamics (CFD) simulations and experiments helps engineers predict and improve the effectiveness of superhydrophobic surfaces in reducing drag. This optimization approach leads to significant enhancements in fuel efficiency and performance across a range of fluid-flow systems, including marine vessels and aircraft. This study models the phenomena of velocity and temperature slip, coupled with MHD, within the context of nanofluid flow undergoing bioconvection over a stretching sheet. Subsequently, the study seeks to analyze the resulting effects on heat and mass kinematics. The bvp4c solver effectively calculates analytical solutions for the reduced problem obtained through similarity transformation from the underlying partial differential equations. Velocity and temperature slip both impact temperature, with velocity slip increasing heat transfer rates and temperature slip decreasing them. The thermal radiation parameter enhances nanoparticle concentration, although it’s offset by an increased Lewis number. Brownian motion amplifies mass transfer, but the thermal radiation parameter hampers it. The escalation in the microorganism density profile correlates with the increase in both the Bioconvection Lewis number and the Peclet number. Likewise, as thermophoresis parameters and the bioconvection constant increase, the microorganism density along the profile also rises.