Additional Inclusion Research Articles

Cardiac arrest in obstetric patients receiving anaesthetic care: results from the 7th National Audit Project of the Royal College of Anaesthetists.

The 7th National Audit Project (NAP7) of the Royal College of Anaesthetists studied peri-operative cardiac arrest. Additional inclusion criteria for obstetric anaesthesia were: cardiac arrest associated with neuraxial block performed by an anaesthetist outside the operating theatre (labour epidural analgesia); and cardiac arrest associated with remifentanil patient-controlled analgesia. There were 28 cases of cardiac arrest in obstetric patients, representing 3% of all cardiac arrests reported to NAP7, giving an incidence of 7.9 per 100,000 (95%CI 5.4-11.4 per 100,000). Obstetric patients were approximately four times less likely to have a cardiac arrest during anaesthesia care than patients having non-obstetric surgery. The single leading cause of peri-operative cardiac arrest in obstetric patients was haemorrhage, with underestimated severity and inadequate early resuscitation being contributory factors. When taken together, anaesthetic causes, high neuraxial block and bradyarrhythmia associated with spinal anaesthesia were the leading causes overall. Two patients had a cardiac arrest related to labour neuraxial analgesia. There were no cardiac arrests related to failed airway management or remifentanil patient-controlled analgesia.

Antioxidant, enzymes inhibitory, physicochemical and sensory properties of instant bio-yoghurts containing multi-purpose natural additives.

This study aimed to assess the antioxidant, enzyme inhibitory, physicochemical and sensory properties of instant bio-yoghurts containing multi-purpose natural additives. Multi-purpose natural additives were formulated with three natural additives (sweet detar seed, ginger rhizome, and hibiscus calyx flours, as a thickener, flavourant and colourant, respectively) blends at proportions derived from the Design Expert. The additives' synthetic counterparts were formulated with sodium carboxymethylcellulose, vanilla flavor, and red colourant at the same proportions. After that, yoghurt was produced and the additives blends were incorporated into it either in aqueous extract or flour form, yielding bio-yoghurts designated multi-purpose natural additive extract-containing yoghurt (MNAE-yoghurt), multi-purpose natural additive flour-added yoghurt (MNAF-yoghurt), and their multi-purpose synthetic additives-containing counterparts (MSAE-yoghurt and MSAF-yoghurt). A commercially-available bio-yoghurt served as a control. All the yoghurts were lyophilized to obtain instant bio-yoghurts. Subsequently, bioactive components (total phenolics, tannins, total flavonoids and saponins), antioxidants and enzymes [alpha-amylase, alpha-glucosidase, pancreatic lipase, and angiotensin 1-converting enzyme (ACE)] inhibitory activities, as well as proximate, physicochemical and sensory qualities of the bio-yoghurts were determined. The MNAE-yoghurt and MNAF-yoghurt had higher bioactive constituents, total titratable acid levels, and more potent antioxidant and enzyme inhibitory properties, but a lower pH than their synthetic counterparts and the control. The total phenolics, tannins, total flavonoids and saponins levels of MNAE-yoghurt and MNAF-yoghurt were 14.40 ± 0.24 and 16.54 ± 0.62 mg/g, 1.65 ± 0.04 and 1.74 ± 0.08 mg/g, 4.25 ± 0.03 and 4.40 ± 0.02 mg/g, 0.64 ± 0.01 and 0.66 ± 0.02 mg/g, respectively. Among the natural multi-purpose additives-containing bio-yoghurts, MNAF-yoghurt had higher bioactive constituents and stronger antioxidant and enzymes inhibitory properties. Its α-amylase, α-glucosidase, ACE, and pancreatic lipase IC50 values were 72.47 ± 0.47, 74.07 ± 0.02, 25.58 ± 2.58, and 33.56 ± 29.66 μg/mL, respectively. In contrast, MNAE-yoghurt had the highest protein (13.70 ± 0.85%) and the lowest fat (2.63 ± 0.71%) contents. The sensory attributes of all the bio-yoghurts fell within an acceptable likeness range. Overall, the inclusion of multi-purpose natural additives blends enhanced the instant bio-yoghurts' nutritional, health-promoting, and sensory qualities.

Use of an enzyme with phytase activity in fatting young pigs

Complete feeding is one of the decisive factors for achieving high animal productivity. Therefore, an essential task of modern pig breeding is to reduce costs by increasing the digestibility of digested feed nutrients by the animal's body. One of the significant ways necessary to solve the problem can be the additional inclusion of biologically active substances in the compound feed for farm animals, namely, modern enzyme preparations of a new generation. The animal organism needs them to increase the digestibility of nutrients supplied with food. Our study aims to study the effect of the Feedbest P5000 GT enzyme preparation as part of compound feed on the growth, development and feed costs of fattening young pigs. A scientific and economic experiment was conducted on young pigs of a large white breed aged 60 to 210 days to achieve this goal. For the investigation, four groups of young pigs, 12 heads each, were formed according to the principle of analogue groups, taking into account breed, sex, age, and live weight. They were keeping the animal group. The authors weighed every 30 days and took measurements of the animals. In addition, they considered the consumption of feed and leftovers for the next day to determine the effect of Feedbest P5000 GT on the growth and development of fattening young pigs. The use of the Feedbest P5000 GT enzyme preparation in compound feeds made it possible to increase the average daily gain in live weight of young pigs of the experimental groups by 4.8, 9.3 and 6.8% and reduce feed costs by 4.7, 8.6 and 6.5% compared to with the young of the control group. The best indicators were found in the animals of the 2nd experimental group, where the studied enzyme preparation was additionally introduced into the feed composition in the amount of 90 g/t.

Effect of molasses on nutritive value and in-vitro digestibility of elephant grass silage

Abstract Ensiling preserving a forage crop and its nutrients to feed later on as silage. In this study, elephant grass was ensiled with varying levels of molasses as an additive to evaluate its effect on the nutritive value and in-vitro digestibility of the silage. Four treatments of Pennisetum purpureum grass silage were produced with the inclusion of molasses at 0 (T1), 2.5 (T2), 5 (T3), and 7.5 % (T4) inclusion levels. Elephant grass ensiled with higher levels of molasses inclusions (T3, and T4) had significantly higher (p < 0.05) dry matter, crude protein, nitrogen-free extract, and lactic acid than T1 and T2 silages. However, T1 and T2 silages had significantly higher (p < 0.05) crude fibre and ash contents. Furthermore, silage without molasses inclusion (T1) had significantly higher (p < 0.05) in most of the fibre fractions compared to other silages in this study. At 6 and 15 hours, there were no significant differences (p > 0.05) in the means of in-vitro gas production. However, gas production was significantly higher (p < 0.05) in silages with the inclusion of additives (T4, T3, and T2) at 9, 12, 18, 21, and 24 hours of incubation. Conspicuously, silages containing graded levels of molasses as an additive had significantly higher (p < 0.05) digestibility and organic matter digestibility than the silage without molasses. The methane gas and metabolisable contents were significantly higher (p < 0.05) in T3 and T4 silages than T1 and T2 silages. However, T3 had significantly the highest (p < 0.05) gas volume followed by T2, T4, and T1 silages. It can be concluded that our H1 hypothesis was confirmed and the inclusion of molasses as an additive in elephant grass silage resulted in improved dry matter, crude protein, lactic acid contents, reduced fibre fractions, and superior in-vitro digestibility values as well as relatively better gas production by the silage.

Review of Mixing Mechanism and Performance of Natural Rubber with Bituminous Materials

Road degradation is a common problem in Malaysia which caused by weather changes, expanding loads as well as the effects of ageing, moisture and temperature results in high maintenance expenses on conventional bitumen pavement. Therefore, it has been recommended on the modification of bitumen as a substitute technique to address this issue and extend the pavement’s lifespan. This study addresses the inadequacy of existing solutions by focusing on the direct mixing approach and the use of pre-treatment using chemical solvent and some additives specifically on epoxidized natural rubber, natural rubber latex and cup lump natural rubber (CLNR). Additionally, this study intends to give a brief summary of how bitumen performance is improved by the inclusion of additives or modifiers by emphasizing the key attributes of modified bitumen after the addition of modifiers. Further information is also provided on the quantity and application method of each addition in order to determine the ideal value for different applications. This study will examine the use of several additives based on past research, such as polyphosphoric acid, Zychotherm, as well as the use of toluene and xylene to maintain the homogeneity of the rubberized bitumen. Studies on the usage of cup lump natural rubber (CLNR) are not common, thus future study should investigate more closely at CLNR and its mixing technique. This research contributes to the field by providing insights into the practical application of modified bitumen for sustainable road construction, especially in regions with a significant rubber industry.

Study of the influence of micro- and nano-cellulose on the growth and carbonation kinetics of portlandite crystals

Restoration of historical buildings contributes to the preservation of history and identity of the cities, but also, in the current climate crisis, an alternative solution to reduce the environmental impact of the construction sector, which is one of the main global contributors to green-house gas emissions and waste production. It can be also claimed that the most sustainable building is the one that has already been built. An important aspect to consider for the restoration of built heritage is the use of compatible materials, such as lime-based mortars, that should be preferred over cement. However, their slow setting and hardening (via carbonation), and, in some cases, poor durability prevent their full acceptance and widespread use. One course of action is to improve the quality of the binder via an innovative approach: inclusion of natural organic additives during the slaking process of CaO. This is expected to have a higher impact than their inclusion in the mortar’s mix design. In the present work the analysis of the growth of Ca(OH)2 crystals following their crystallization in the presence of micro- and nano-cellulose is studied, together with the morphological changes that these additives induce on portlandite crystals. Moreover, the study of the carbonation kinetics of the modified portlandite crystals gives insights on the effect that these additives have on the quality of the binder. The promising results highlight the potential of micro- and nano-cellulose as sustainable additives for lime-based binders. Furthermore, these additives can be obtained from industrial wastes, promoting a circular economy.

Boosting the performance of Quasi-2D perovskite Light-Emitting diodes by tailoring molecular configurations of Carboxyl-Based additives

Quasi two-dimensional (quasi-2D) perovskites have shown huge potential for perovskite light-emitting diodes (PeLEDs). Nevertheless, the serious non-radiative recombination induced by numerous defects in polycrystalline quasi-2D perovskite films hinders their further development. Herein, three carboxyl-based additives with different molecular configurations, i.e. butyric acid (BAC), glutaric acid (GAC) and tricarballylic acid (TAC), are adopted as passivation agents for quasi-2D PeLEDs. Benefiting from the strong coordination interaction between –COOH and perovskites, the inclusion of carboxyl-based additives can effectively optimize film morphologies, regulate the distribution of small-n phases, passivate defects and enhance film stability. With the increase of the carboxyl group number and molecular spatial dimension of carboxyl-based additives, more compact and smoother quasi-2D perovskite films, together with narrower phase distribution, lower defect density and better stability, can be obtained. Consequently, the unpacked quasi-2D PeLED treated with TAC, which is tested in the ambient air with the relative humidity of about 50 %, delivers an external quantum efficiency (EQE) of 14.21 % and prolonged operational lifetime (T50) of 2160 s, while the pristine device only gives an EQE of 7.63 % and T50 of 460 s. Our work provides guidance for boosting the performance of quasi-2D PeLEDs by rationally tailoring molecular configurations of carboxyl-based additives.

Enhancing Rural Market Access and Value Chain Integration for Sustainable Agricultural Development in Nigeria: A Study of Constraints, Strategies, and Implications

This study investigates rural market access and value chain integration in Nigeria’s diverse agroecological zones—Northern Sahel, Central Savannah, and Southern Rainforest—to enhance sustainable agricultural development. Employing mixed methods, quantitative surveys and qualitative interviews were conducted with smallholder farmers and key stakeholders. The findings reveal variations in market access challenges, value chain engagement, and the impact of strategies across zones. Challenges encompass transportation costs, distance to markets, lack of market information, and post-harvest losses. Farmer cooperatives emerged as a pivotal strategy, enhancing collective bargaining power. For zone-specific interventions, infrastructure development, market information dissemination, value addition, and financial inclusion programs are recommended. This research contributes to localized approaches for addressing challenges and optimizing opportunities in enhancing rural market access and value chain integration, fostering resilient and inclusive agricultural growth.

КВІТКОВИЙ ТУРИЗМ В КАРПАТСЬКОМУ РЕГІОНІ УКРАЇНИ ЯК ТРЕНД РОЗВИТКУ ГАЛУЗІ

The purpose of the scientific research is to reflect on the example of the Carpathian region of Ukraine the resources of flower tourism, to study the geography of their distribution, as well as the current state and prospects for the development of this type of tourism within the region. Methodology. In the study, the method of scientific systematization of information is used to identify places of flower tourism in the Carpathian region of Ukraine; the method of field research to identify the specifics of the activities of farms engaged in the cultivation of flowering plants; the location of resources within the region is displayed using the cartographic method. Results. The concept of "flower tourism" is specified, in particular, attention is focused on its belonging to niche types of tourism. The types of resources of flower tourism of the Carpathian region of Ukraine are summarized and their classification by the method of growth and purpose of use is proposed. The list of places for flower tourism in the region is grouped using such parameters as: type of location, presence of a flowering plant, flowering period, etc. It was found out that Zakarpattia region is the leader in the number of flower locations. The region has a wide range of flowering plants - sakura, lavender, crocuses, daffodils, magnolias, tulip trees, and almonds. The map of the geography of flower tourism resources allows to draw conclusions about their location within the region, as well as proximity or distance from the main tourist centers. On the example of the Lviv tour operator "Vidviday", selected tourist products involving places of flower tourism were analyzed. It was revealed that an essential feature of all flower tours is the additional inclusion of other tourist objects in the program of stay. The problems of development are summarized, and conclusions are made regarding the prospects for the development of flower tourism in the region. The scientific novelty of the results is analysis of the resource potential of flower tourism in the Carpathian region of Ukraine, study of created tourist products with the involvement of these resources, as well as justification of the possibilities of their further use in tourism. The practical importance. The obtained research results will be used in the process of forming tourist products in the territory of the Carpathian region of Ukraine, as well as in the educational process of training future specialists in the specialty "Tourism and Recreation". In addition, the findings can be useful for state authorities for the formation of strategies, as well as the implementation of state or regional tourism development programs.

Implementing evidence-based practices in rural settings: a scoping review of theories, models, and frameworks.

Rural healthcare has unique characteristics that affect the dissemination and implementation of evidence-based interventions. Numerous theories, models, and frameworks have been developed to guide implementation of healthcare interventions, though not specific to rural healthcare. The present scoping review sought to identify the theories, models, and frameworks most frequently applied to rural health and propose an approach to rural health research that harnesses selected constructs from these theories, models, and frameworks. This resulting synthesis can serve as a guide to researchers, policy makers, and clinicians seeking to employ commonly used theories, models, and frameworks to rural health. We used the Scopus abstract indexing service to identify peer-reviewed literature citing one or more of theories, models, or frameworks used in dissemination and implementation research and including the word "rural" in the Title, Abstract, or Keywords. We screened the remaining titles and abstracts to ensure articles met additional inclusion criteria. We conducted a full review of the resulting 172 articles to ensure they identified one or more discrete theory, model, or framework applied to research or quality improvement projects. We extracted the theories, models, and frameworks and categorized these as process models, determinant frameworks, classic theories, or evaluation frameworks. We retained 61 articles of which 28 used RE-AIM, 11 used Community-Based Participatory Research (CBPR) framework, eight used the Consolidated Framework for Implementation Research (CFIR), and six used the integrated-Promoting Action on Research Implementation in Health Services (iPARIHS). Additional theories, models, and frameworks were cited in three or fewer reports in the literature. The 14 theories, models, and frameworks cited in the literature were categorized as seven process models, four determinant frameworks, one evaluation framework, and one classic theory. The RE-AIM framework was the most frequently cited framework in the rural health literature, followed by CBPR, CFIR, and iPARIHS. A notable advantage of RE-AIM in rural healthcare settings is the focus on reach as a specified outcome, given the challenges of engaging a geographically diffuse and often isolated population. We present a rationale for combining the strengths of these theories, models, and frameworks to guide a research agenda specific to rural healthcare research. https://osf.io/fn2cd/.

Оценка эффективности использования конопляного и льняного жмыхов в рационе дойных коз на фоне пробиотического вещества

The paper evaluates the efficiency of hemp and flax cakes in the diet of dairy goats against the background of inclusion of enzymatic probiotic substance, in the conditions of the Southern Urals. Additional inclusion of probiotic preparation Cellobacterin+ promoted a significant increase in digestibility of crude fiber (by 4.9-5.5%), crude protein (by 3.3-4.1%), crude fat (by 3.8-5.1%), as well as an increase in average daily milk yield by 2.1-7% (p≤0.05).

THE RESULTS OF THE APPROBATION OF METHODS OF SYNCHRONIZATION OF LIBIDO SEXUALIS OF HITSYNCH AND OVSYNCH ON COWS OF MEAT PRODUCTIVITY

The article presents data on the comparative effectiveness of synchronization schemes of the sexual cycle in cattle using the Hitsynch and Ovsynch methods, various GnRH, prostaglandin F2a, and estrogens were used in synchronization schemes to activate sexual processes and increase fertilization. In order to increase their effectiveness, biologically active substances were included in the synchronization schemes. The aim of the study was to determine the effectiveness of various synchronization schemes when biologically active substances are included in them. The authors note that stimulation of the genitals using the methods of synchronization of sexual libido of Hitsynch and Ovsynch with the additional inclusion of biologically active substances in the schemes significantly improves the arrival of cows in libido and increases fertilization. These indicators were more pronounced when synchronizing sexual libido using the Hitsynch method. The novelty of the conducted research is the determination of effective modern schemes of synchronization of sexual libido. It was found that the complex use of hormonal drugs "Surfagon", "Oestrophan" biologically active substances vitamin complex "Tetravit" and estrogenic hormone ECP activates the manifestation of sexual processes stimulates the manifestation of sexual libido and increases the fertilization of cows.

The Impact of Family Communication on Adolescent Satisfaction with Family Life Across Different Family Structures

The Circumplex Model of Marital and Family Systems is one of the most widely used approaches in family studies. This model assumes that family communication is an important element in achieving positive family functioning because it allows family members to alter their levels of flexibility and cohesion. While this theoretical approach has been widely used and tested there are still some gaps in the empirical evidence on the universality of its assumptions. Considering that adolescents today live in a wide variety of families, that are very diverse according to their structures, it is important from an ethical standpoint to test the universality of any theoretical framework that is used in family interventions. This study therefore sought to investigate whether there are differences in satisfaction with family life and family communication in families with different structures and whether family communication is an important correlate of satisfaction with family life in all types of families, using data from a study of adolescents from Zagreb, Croatia (N = 4 821). Linear regression was used to evaluate the association of family satisfaction (dependent variable) with family communication and parental marital status (predictor variables) with the additional inclusion of interaction effects between family communication and parental marital status. The results of this study have shown that adolescents are generally satisfied with their family life and that there are differences in perceived family satisfaction and family communication between adolescents regarding the marital status of their parents. The results presented in this paper support the main hypothesis that in families with adolescents, family communication is strongly associated with family satisfaction, independently of parental marital status. The findings suggest that interventions aimed at improving family communication skills inadolescent families could benefit all families with adolescents.

Feasibility of tongue image detection for coronary artery disease: based on deep learning.

Clarify the potential diagnostic value of tongue images for coronary artery disease (CAD), develop a CAD diagnostic model that enhances performance by incorporating tongue image inputs, and provide more reliable evidence for the clinical diagnosis of CAD, offering new biological characterization evidence. We recruited 684 patients from four hospitals in China for a cross-sectional study, collecting their baseline information and standardized tongue images to train and validate our CAD diagnostic algorithm. We used DeepLabV3 + for segmentation of the tongue body and employed Resnet-18, pretrained on ImageNet, to extract features from the tongue images. We applied DT (Decision Trees), RF (Random Forest), LR (Logistic Regression), SVM (Support Vector Machine), and XGBoost models, developing CAD diagnostic models with inputs of risk factors alone and then with the additional inclusion of tongue image features. We compared the diagnostic performance of different algorithms using accuracy, precision, recall, F1-score, AUPR, and AUC. We classified patients with CAD using tongue images and found that this classification criterion was effective (ACC = 0.670, AUC = 0.690, Recall = 0.666). After comparing algorithms such as Decision Tree (DT), Random Forest (RF), Logistic Regression (LR), Support Vector Machine (SVM), and XGBoost, we ultimately chose XGBoost to develop the CAD diagnosis algorithm. The performance of the CAD diagnosis algorithm developed solely based on risk factors was ACC = 0.730, Precision = 0.811, AUC = 0.763. When tongue features were integrated, the performance of the CAD diagnosis algorithm improved to ACC = 0.760, Precision = 0.773, AUC = 0.786, Recall = 0.850, indicating an enhancement in performance. The use of tongue images in the diagnosis of CAD is feasible, and the inclusion of these features can enhance the performance of existing CAD diagnosis algorithms. We have customized this novel CAD diagnosis algorithm, which offers the advantages of being noninvasive, simple, and cost-effective. It is suitable for large-scale screening of CAD among hypertensive populations. Tongue image features may emerge as potential biomarkers and new risk indicators for CAD.

Alarm therapy for nocturnal enuresis in children: A literature review

AbstractNocturnal enuresis is a common childhood problem impacting the quality of life of children and families. Treatment with an enuresis alarm is recommended for 8–12 weeks by the International Children's Continence Society as first line management of monosymptomatic nocturnal enuresis. However, the effectiveness of alarm therapy varies between 80% and 45.9%. There is minimal evidence within the literature exploring the factors impacting this varying response to alarm therapy. Therefore, this literature review aims to explore factors that impact the effectiveness of the enuresis alarm as a treatment for nocturnal enuresis, in children aged 5–17 years. Literature searches were conducted on MEDLINE (Ovid), SCOPUS and CINAHL Databases. The PRISMA tool was used to report the data in the search strategy. The inclusion criteria of children aged 5 to 17 years was chosen based on International Children's Continence Society Guidelines. English language, academic journals and studies in the past 10 years were selected as additional inclusion criterion to identify the most recent, robust literature for the review. All 13 primary research articles were critiqued using the Caldwell Framework. Data were extracted and presented in table format highlighting study methodology, sample, duration of treatment, relevance to review topic and key findings. The findings highlight factors influencing the effectiveness of alarm therapy related to the impact on the child and family, heighten arousal to the alarm, the duration of therapy, age of child and the impact of overlearning. This review provides health professionals with an insight into strategies that may help children and their family to respond successfully to enuresis alarm treatment.

Experimental investigation and numeric modelling of the impact performance of basalt fiber reinforced geopolymer concrete

Geopolymer concrete (GC) has been found to have better results than Portland cement concrete (PCC), including lower carbon dioxide emissions, higher compressive strength, and greater durability. The study aims to determine the effects of basalt fiber on GC due to the impact caused by the sudden loading effect. Samples were prepared with different mixing ratios for the experimental process, with PCC used as the control sample. Basalt fibers were added to the samples in three different ratios based on optimal mixing ratios determined through physical and mechanical tests, such as UPV (Ultrasonic Pulse Velocity), compressive strength, and flexural strength. Subsequently, fibrous samples were analyzed using SEM (scanning electron microscopy) and EDS (energy dispersive spectroscopy). A drop-weight experiment was conducted on GC plates measuring 50×50×5 cm, which contained two different fiber ratios that yielded the best mechanical and physical properties. The results were analyzed using numerical modeling methods. No changes in content were made. The sample with the highest impact resistance was found to be the 2% basalt fiber-reinforced GC, with a displacement value 21.21% lower than PCC. The language used is clear, concise, and objective, with a formal register and precise word choice. The text follows a logical structure with causal connections between statements and adheres to conventional academic formatting and citation styles. The ANSYS modeling results indicated an 89.63% similarity with the experimental data regarding the displacement values. Additionally, the study demonstrated that the inclusion of basalt fiber additives enhances the impact resistance of geopolymer concrete. Furthermore, numerical modeling can predict the impact behavior of concrete to a significant extent, eliminating the need for experimental processes.

Performance of laying hens fed diets incorporated with feather-based feed additive

A comprehensive and in-depth understanding of modern industrial poultry production technology is a vital condition for the development of poultry enterprises. Among the factors that determine poultry farming's development, the state and development of the feed base are of paramount importance. One of the promising directions for organizing rational poultry feeding based on self-produced feed is the use of new feed sources in compound feeds that have a multifaceted positive impact on poultry health. This study aimed to determine whether feeding feather meal induces changes in the body weight of laying hens, feed consumption, and egg production. The experiment was conducted on laying hens of the Hy-Line Brown W-36 breed without beak trimming, aged from 21 to 34 weeks at an industrial poultry farm. The chickens were placed in standard cages arranged in 6 tiers (with eight chickens per cage) and were distributed into five randomized groups. Four diets were formulated with the inclusion of feather-based feed additives in the base diet at levels of 2.0, 2.5, 3.0, or 3.5 kg per ton, while the control group was maintained on the standard diet. Research results using feather meal as part of the compound feed for laying hens have revealed that the inclusion of this additive had a positive impact on the live weight dynamics of Hy-Line Brown laying hens. Positive trends in absolute live weight gains were observed in the experimental groups compared to the control group, with EG1 showing an increase of 56.78 g (4.8%), EG2 with 43.66 g (3.7%), EG3 with 33.26 g (2.8%), and EG4 with 25.75 g (2.1%). The highest retention rate of laying hens was recorded in the first (EG 1) and second (EG 2) experimental groups: 98.9% and 97.9% respectively. The difference in retention between the first experimental group and the control group was 4.1%, while between the second experimental and control groups, it was 3.1%. The feather meal feed additive is an effective protein supplement, and research has revealed its positive influence on live weight gains and the survival of laying hens. The most effective level is 2 kg per ton of compound feed, which can be explained by the data observed in EG1.

Multipurpose pigment printing and functional finishing of cellulosic fabrics

AbstractFunctional fabrics that are economical and environmentally friendly are desired for many applications. Here in, individual inclusion of different additives, such as softeners, polyurethane, polyethylene glycol (PEG‐600) and benzophenone in suitable pigment printing formulation were applied to various cellulose containing fabrics, using flat screen and microwave curing methods. The imparted multifunctional and performance finishes to cellulosic fabrics namely ultraviolet (UV) protection, antibacterial, anti‐crease, and softening were evaluated. The developed functional properties and the depth of the pigment prints produced are governed by the nature of the substrate, concentration/location/distribution in addition to fixation of the added active compounds and pigment colourants. The surface alteration, morphological modifications, and immobilisation of the certain active components onto the printed substrates have been confirmed by scanning electron microscopy and energy‐dispersive X‐ray spectroscopy analysis for selected samples.

Alumina and titanium nanoparticles to diesel–Guizotia abyssinica (L.) biodiesel blends on MFVCR engine performance and emissions

Deteriorating air quality and diminishing fossil fuel reserves drive the demand for alternative fuels. Biodiesel from animal and plant sources appears promising, but it has drawbacks like lower thermal efficiency and higher fuel consumption. One solution is exploring Nano additive biodiesel for internal combustion engines to address these limitations. The present research focuses on Guizotia abyssinica (L.) (GA) crops and the synthesis of biofuels from the bioresource and the aluminium oxide (Al2O3) and titanium dioxide (TiO2) nanoparticles. During nanoparticle characterization in X-ray diffraction (XRD), the interplanar spacing for the most intense peaks of (222) and (101) in Al2O3 and TiO2 was observed to be 2.63 and 3.48, respectively. Scanning Electron Microscopy (SEM) confirmed the formation of Al2O3 and TiO2. In the experimental evaluation, a multi-fuel variable compression ratio (MFVCR) engine was used to evaluate the performance and TESTO350 for the emission analysis. Nano additive biodiesel achieved a peak cylinder pressure of 55.19 bar and reduced CO emissions by 9.78 % compared to other biodiesel blends. The inclusion of nano additives in biodiesel resulted in a maximum brake thermal efficiency of 32.99 % and a minimum brake-specific fuel consumption of 0.362 kg/kWh compared to other fuels in the study.

EFFICIENCY OF APPLICATION OF THE COMBINED HEPATOPROTECTOR IN COMPLEX TREATMENT OF CHRONIC PANCREATITIS WITH CONCOMITANT LIVER DAMAGE

SUMMARY. Comorbidity of chronic pancreatitis (CP) and chronic viral hepatitis C (CVHC) is quite common and problematic, even after etiotropic treatment of viral hepatitis C infection.
 The aim – to investigate the state of the functional capacity of the pancreas and general clinical and selected biochemical parameters of patients with CP against the background of treated CVHC under the influence of the proposed complex treatment with the additional inclusion of the hepatotrophic drug heparizin (HZ).
 Material and Methods. 45 patients with CP comorbid with CVHC were studied. All patients were examined according to generally accepted algorithms and received a generally accepted complex of treatment according to the protocol (GAT) for CP in accordance with the order of the Ministry of Health of Ukraine No. 638 dated 2014 and CVHC – according to the Clinical Guideline of the Ministry of Health of Ukraine, based on evidence "Viral Hepatitis C" dated 2020. All outpatient patients with a comorbid course of CP and CVHC were divided into 2 groups to study the effectiveness of the proposed correction programs: 1 group (20 patients) received a generally accepted complex of treatment according to the protocol (GAT) for three months, Group 2 (GAT+HZ) – 25 patients with CP and CVHC) – received GAT with the additional inclusion of the hepatotrophic agent Heparizin PLC, 1 capsule 3 times a day after meals for 3 months.
 Results. A more significant level of effectiveness of the treatment complex with the additional inclusion of the hepatotrophic drug heparizin was established in relation to this protocol treatment for the restoration of the functional and structural state of the pancreas according to the studied parameters: the content of fecal α-elastase increased by 54.4 % vs. 39.9 %, respectively, and glucose content decreased – by 15.6 % vs. 10.0 %, the co-program score decreased – by 40.2 % vs. 25.1 %, the US score of the software structure decreased – by 74.4 % vs. 33.6 % (p <0.05).
 Conclusions: The reliable positive effect of heparizin on the disturbed parameters of the functional state of the pancreas and liver in CP in combination with CVHC was proven and allowed to assert the anti-inflammatory activity of heparizin, optimizing its effect on protein metabolism and functions of the pancreas and liver. It is recommended to additionally include the hepatotrophic agent heparizin to the protocol complex therapy of patients with chronic pancreatitis against the background of treated etiologically CVHC at the stage of outpatient rehabilitative treatment.