Impact Of COVID-19 Research Articles

5164 Long COVID patients with menstrual symptoms: a retrospective study in Japan

Abstract Disclosure: F. Otsuka: None. Y. Sakurada: None. Y. Matsuda: None. T. Hasegawa: None. Y. Otsuka: None. Y. Nakano: None. K. Tokumasu: None. K. Yamamoto: None. N. Sunada: None. H. Honda: None. H. Hagiya: None. K. Ueda: None. It has been recognized that about one third of patients may suffer from prolonged illness after surviving from the acute phase of COVID-19. Various symptoms of the prolonged illness have been evaluated by many institutions including WHO. However, the mechanisms of the prolonged symptoms have yet to be elucidated. Long COVID is a complicated illness that develops after SARS-CoV-2 infection, independent of the severity of COVID-19. Long COVID is defined as symptoms that occur within 3 months after the initial infection and persist for at least 2 months. The major symptoms of long COVID include general fatigue, post-exertional malaise, headache, insomnia, dyspnea, cognitive dysfunction, low-grade fever, and muscle pain. Proposed pathophysiological mechanisms of long COVID include pathogen persistence and viral reactivation, immune dysregulation and autoimmunity, neurological abnormalities, tissue damage due to hypoperfusion and/or microclots, autonomic and endocrine dysfunctions, and dysregulation of microbiomes. In the present study, we aimed to elucidate the impact of long COVID on female reproductive health. In this retrospective study, medical records of patients who visited our long COVID clinic and clinical trends of their menstrual symptoms were evaluated. In our study, of 349 female patients who visited our clinic between Feb 2021 and Mar 2023, 223 patients with long COVID (18-50 years) were included. It was revealed that 44 females (19.7%) had menstrual symptoms associated with long COVID. The patients with menstrual symptoms were significantly older than those without menstrual symptoms (42.5 vs. 38 years). The percentage of patients with menstrual symptoms was higher during the Omicron phase (24%) than during the Preceding (13%) and Delta (12%) phases. Cycle irregularity (63.6%) was the most frequent menstrual symptom, followed by severe pain (25%), heavy bleeding (20.5%), perimenopausal symptoms (18.2%), and premenstrual syndrome (15.9%). Fatigue and depression were the most frequent complications with menstrual complaints. Scores indicating fatigue and QOL were significantly worse in long COVID patients with menstrual symptoms. Endocrine examinations showed significantly increased cortisol levels in patients with menstrual complaints although plasma adrenocorticotropin levels were not altered. Hence, long COVID has an impact on women’s reproductive and mental health. Presentation: 6/1/2024

The intensity of regional food trade among the Western Balkan countries during periods of crisis

This study explores the intensity of food trade among the Western Balkan (WB) countries (Albania, Bosnia and Herzegovina, Montenegro, North Macedonia, and Serbia) during periods of crisis, emphasizing the impact of COVID-19 and the Ukrainian-Russian conflict on regional trade dynamics. The impact of this crisis was measured over three analyzed years: 2018, representing a reference year for comparison, then 2020 as the year affected by COVID-19, and 2022, being affected by the pandemic as well as the Ukrainian-Russian crisis. All data collected are from the “Trade Statistics for International Business Development Database”. Conclusions about the intensity of exchange of agricultural and food products within the WB region were obtained by calculating Regional Intensity of Trade of Export (RITE) and Regional Intensity of Trade of Import (RITI). Higher values than 1 indicate intensity in trade or dominance of trade in specific products with a particular region compared with the trade with the world. In the case of trade among the WB countries, the COVID-19 crisis did not affect the increase in trade volume. However, there was an increase in intra-regional trade by about 50% when compared with 2020 and 2022. The RITE coefficients for all countries except Albania were greater than 1, indicating intensified export of agricultural and food products to the WB region compared with their global export. The RITI index is very important in crisis, as it somewhat answers the question of who "feeds" the country during crises. All WB countries had the RITI indices greater than 1, indicating a higher intensity of food imports from the region compared with the world. According to this research, the RIT coefficients measured generally declined in the years of crises, meaning that the countries shifted their export focus to other regions but still the most significant foreign and intense trade partners in agricultural and food products were countries from the region.

Resurgence of influenza and enterovirus infections in Taiwan post-COVID-19: A nationwide surveillance study

BackgroundThe global impact of COVID-19 has prompted profound shifts in public health policies. The epidemiology of respiratory infectious disease may change in the post-covid era. This study investigates the repercussions of these policies on respiratory infectious diseases, specifically the resurgence of severe influenza and enterovirus infections in the post-COVID-19 era. MethodsExamining the period from January 2020 to December 2023, our nationwide study analyzes data from the Taiwan Centers for Disease Control and Our World in Data. Two distinct phases, containing (Week 1, 2020, to Week 43, 2022) and coexisting (Week 44, 2022, to Week 50, 2023), are scrutinized, emphasizing policy changes and their potential impact on epidemiology. ResultsEpidemiological trends reveal a decline in COVID-19 and all-cause pneumonia during the co-existing period but a notable rise in severe influenza and enterovirus infections. Interrupted time series analysis confirms the surge in severe influenza and enterovirus cases post-restriction ease. ConclusionThe post-COVID-19 era introduces challenges with the resurgence of traditional respiratory diseases, necessitating continuous surveillance, timely non-pharmaceutical interventions, and vaccination as crucial strategies. Vigilance and targeted measures by policymakers and healthcare providers are imperative to navigate the evolving landscape of respiratory infectious diseases in the aftermath of the pandemic.

Impact of COVID-19 on referrals to paediatric liaison psychiatry at Children's Health Ireland at Crumlin as the pandemic moved to endemic status.

Rates of acute mental health presentations in youth were increasing pre-pandemic internationally. Longitudinal studies following COVID-19 attest to ongoing deterioration in youth mental health, recognising adverse unintended consequences following public health restrictions. To examine whether the initial post-COVID-19 increase in mental health presentations persisted following the reclassification of COVID-19 to endemic status, accompanied by the removal of most restrictions. All referrals to paediatric liaison psychiatry (PLP) between January 2018 and December 2022 in a Dublin tertiary children's hospital were included in the study. An interrupted time series analysis with autoregressive integrated moving average models was conducted, examining referrals with respect to different phases of COVID-19 and application of public health restrictions. Some 1385 referrals to PLP were received over the 5-year study. There was a significant decrease in PLP referrals immediately post-COVID-19, followed by a significant and sustained increase as the pandemic progressed and moved to endemic status. Public health restriction phases had a unique effect on those presenting with suicidal ideation, with a significant increase in the number of referrals. There was no effect of restrictions on other clinical profiles. Increased referrals for youth with mental health difficulties, reported during the COVID-19 pandemic, persisted into the early endemic stage, after COVID-19 public health restrictions ceased. Specific impacts of restrictions on suicidal ideation referrals require further study. Investment in child and adolescent mental health services remains a priority, and future pandemic response strategies need to examine unintended consequences of any enforced public health measure.

Measuring the Collective Community Capacity of a Network to Address Health Inequities during a Public Health Emergency: Findings from the National COVID-19 Resiliency Network.

This study assesses the collective community capacity of the National COVID-19 Resiliency Network (NCRN), a multisectoral network mitigating the disproportionate impact of COVID-19 on minoritized populations. From January to April 2022, we used two concurrent data collection methods: a Collective Community Capacity (C3) survey (n=65) and key informant interviews (KIIs) (n=26). The C3 assessed capacity for creation of a shared vision, engagement in community change, and distributive leadership. KIIs assessed perspectives on network formation and implementation. We used a convergent design and triangulation for interpretation. NCRN has growing collective community capacity. The C3 survey found high capacity for establishing a shared mission and evidence of mutual commitment, trust, and accountability. About three-quarters of respondents strongly agreed that partners addressed social, economic, and cultural barriers related to COVID-19. Interviewees valued NCRN leaders' openness, availability, and willingness to listen. Partners learned from one another, increased their health communication capacity, and supported sustainability. They sought greater opportunities to partner and support decision-making. NCRN developed a collaborative network with a shared vision of improving health equity during and beyond the COVID-19 pandemic, while identifying areas for improvement in distributive leadership. Findings can support other organizations seeking to build collective community capacity to address equity in public health emergencies.

Climate change adaptation benefits from rejuvenated irrigation systems at Kiwere and Magozi schemes in Tanzania

ABSTRACT We examine whether soil moisture and nutrient monitoring tools and Agricultural Innovation Platforms improve farmers adaptive capacity to climate change in the context of two small-scale irrigation schemes in Tanzania. Analysis of household surveys and farmer field books show that these interventions have significantly increased household income and diversification and reduced water use and conflicts. This has contributed to rejuvenating the schemes and increased the willingness to collaborate. Farmers within these schemes report less COVID-19 impact than farmers within surrounding schemes. We argue that the interventions have increased farmers’, and their communities’, resilience and capacity to adapt to climate change.

Assessment of the COVID-19 impact on the Brazilian Unified Health System (SUS) financing: an analysis of the financing dynamics of 2020 and 2021

BackgroundAfter the establishment of the public health emergency of international concern in 2020, health systems worldwide and in Brazil observed the need to apply more extraordinary logistical efforts and possibly resources to combat the imminent pandemic.MethodsUsing the historical series of public expenditures of the National Health Fund (FNS), 2015 to 2021, the number of confirmed cases of COVID-19, and a seasonal ARIMAX model, we sought to assess how the increase in the new virus infections affected the systematic financing of the SUS in Brazil.ResultsThere were signs of seasonality and an increasing trend in the expenditure variable, which in practical terms, only indicated that the resource contributions followed an increasing trajectory already underway before the advent of the pandemic. The 1% increase in COVID-19 cases, with a one-month lag, contributes to the 0.062% increase in the variation in FNS expenditures but a decrease of 0.058% with a two-month lag.ConclusionThe tests showed no evidence to confirm a positive shift on FNS spending growth trajectory due to the increase of COVID-19 cases, only observing a significant increase one month after the occurrence of COVID cases, probably due to their worsening after this period, which was followed by a similar and comparable decrease in percentage of growth in the following month.

The impact of COVID-19 on the debate on open science: a qualitative analysis of published materials from the period of the pandemic

This study is an analysis of the international debate on open science that took place during the pandemic. It addresses the question, how did the COVID-19 pandemic impact the debate on open science? The study takes the form of a qualitative analysis of a large corpus of key articles, editorials, blogs and thought pieces about the impact of COVID on open science, published during the pandemic in English, German, Portuguese, and Spanish. The findings show that many authors believed that it was clear that the experience of the pandemic had illustrated or strengthened the case for open science, with language such as a “stress test”, “catalyst”, “revolution” or “tipping point” frequently used. It was commonly believed that open science had played a positive role in the response to the pandemic, creating a clear ‘line of sight’ between open science and societal benefits. Whilst the arguments about open science deployed in the debate were not substantially new, the focuses of debate changed in some key respects. There was much less attention given to business models for open access and critical perspectives on open science, but open data sharing, preprinting, information quality and misinformation became most prominent in debates. There were also moves to reframe open science conceptually, particularly in connecting science with society and addressing broader questions of equity.

Women's mental health and COVID-19: increased vulnerability and inequalities.

The impact of COVID-19 on mental health has become a relevant object of research. Studies have demonstrated that women have experienced greater mental health challenges, highlighting the importance of public health systems to address women's specific needs. This literature review explores the effects of the coronavirus pandemic on psychological distress among women, aiming to provide a comprehensive understanding of the subject and to explore how these research findings can guide public mental health care responses in crisis settings. A total of 131 studies were analyzed and four dimensions were discussed: study characteristics, factors impacting women's mental health in the pandemic setting, particularities of pregnancy and the postpartum period, and proposed interventions. Most studies exclusively addressed populations of adult women, predominantly during pregnancy and the postpartum period. Anxiety, depression, and stress were the most common outcomes. Lower education and income, preexisting mental health problems, and living alone or with children were risk factors for higher levels of anxiety and depression. A comprehensive care approach supported by public health policies and focused on intersectional factors, including race, socioeconomic status, and access to resources, is necessary to improve women's mental health care response in future crises.

The Incidence of Clinical Injuries among Undergraduate Dental Students: A Prevention Protocol

Dental students are frequently exposed to percutaneous injuries (PCIs) due to the nature of their clinical work, which involves sharp instruments and close patient contact. The COVID-19 pandemic further emphasized the need for stringent biosafety measures and the use of personal protective equipment (PPE). Despite these precautions, injuries remain prevalent, highlighting the need for comprehensive education and training in biosafety and infection control. This study investigates the incidence and causes of injuries among undergraduate dental students during clinical sessions. This study was conducted at the Department of Dentistry, National and Kapodistrian University of Athens, focusing on injuries reported from 2021 to 2024. Data were collected through self-reported clinical records. The primary variables assessed included the type of injury, the instrument involved, the clinical procedure performed, and the immediate actions taken post-injury. Serological testing was conducted on students and patients to assess the risk of the transmission of bloodborne pathogens. The findings reveal a high prevalence of injuries, with needles being the most common cause (51.4%), followed by other tools such as dental probes (25.7%) and burs (8.6%). The most frequent injury type is piercing (74.2%), primarily affecting the fingers (88.6%). Periodontal treatments, restorative procedures, and endodontic treatments are the main activities leading to injuries, with 17.1% of injuries being caused by each. No statistically significant results are recorded. Despite regular medical records for most patients treated by injured students, serological testing shows significant positivity rates for HCV and HBV. Notably, most injured students demonstrate their commitment to safety by adhering to recommended post-exposure protocols, including wound cleaning, disinfecting, and serological testing. Furthermore, the impact of COVID-19 heightened the importance of personal protective equipment (PPE) and reinforced occupational health standards. Our study highlights the critical need for enhanced biosafety awareness and training among undergraduate dental students to reduce injury risks.

Impact of the COVID-19 pandemic on communal religious worshippers’ mental health and the benefits of positive religious coping

BackgroundIn the United Kingdom, onsite religious services were halted during COVID-19 lockdowns, which were followed by various levels of restrictions on communal worship including social distancing, mandatory wearing of face masks, adequate ventilation and a ban on congregational singing and chanting. The aim of our study was to evaluate the impact of closures and changes within places of worship in response to the first lockdown in 2020, to assess the effect of the pandemic on religious practice and worshippers’ wellbeing and religious coping. MethodsParticipants were regular worshippers in the UK, recruited through an online survey using convenience sampling. Respondents were asked about their attitudes to changes to places of worship in the UK and their wellbeing and mental health, including assessment of their risk of depression and anxiety using the Patient Health Questionnaire (PHQ-9) and Generalised Anxiety Disorder Assessment (GAD-7) measures. Questionnaires were completed August to November 2020. Findings939 participants were included in the analysis. Median age was 52.7 years and 66.1% were female. 80.7% identified as Christian. 165 (19.3%) had mild, 45 (5.3%) moderate, 25 (2.9%) moderately severe and 10 (1.2%) severe depression, and 192 (22.5%) had mild, 55 (6.4%) moderate and 27 (3.2%) severe anxiety, according to PHQ-9 and GAD-7 scores, respectively. Nearly half (46.4%) reported that their mood and anxiety levels had worsened and 16.6% reported that they felt the things they were doing in their lives were not worthwhile. The vast majority of respondents (92.7%) reported that prayer had helped them cope with the way they had felt during lockdown: 29.2% and 47.0% reported that it helped moderately and a great deal, respectively. This 76.2% had significantly lower levels of moderate/severe depression and anxiety (adjusted odds ratio: depression 0.37 (95%CI 0.22-0.63), anxiety 0.52 (95%CI 0.31-0.88). InterpretationOur study demonstrates the significant impact of COVID-19 on communal worshippers’ mental health and reinforces the benefits of positive religious coping during the first UK lockdown. Barriers to communal worship participation during lockdowns, including access to appropriate technology, need to be recognised and facilitators identified.

Racial and Gender Disparities among Nephrology Fellowship Trainees: Trends over a Decade and the Impact of COVID-19

Racial and Gender Disparities among Nephrology Fellowship Trainees: Trends over a Decade and the Impact of COVID-19

An Investigation on the Lasting Impact of COVID-19 on Hope, Gratitude, and Forgiveness of College Students' Wellbeing

Abstract : With the COVID-19 widespread, the disruption of the normal routine of the people global wide was predominant. The restrictions abiding the control of the spread of the pandemic were effective in controlling the spread of the virus, but it has remained instrumental in the upheavals of negative emotions amidst the people even after the pandemic period. Most significantly, these protocols have impacted the college students socially and emotionally. To sustain the sense of happiness as well as fulfilment in life, hope, forgiveness, and gratitude are the significant contributors. This study investigated the impact of hope, forgiveness, and gratitude on the college students in the post pandemic era using the Hope Scale, the Gratitude Questionnaire, and the Heartland Forgiveness Scale to collect data. Quantitative analysis was carried out using SPSS; t-tests and ANOVA tests enabled the analysis resulting in the findings that the parents and teachers should encourage pupils to develop good habits and attend specialized trainings on cultivating hope, forgiveness, and gratitude to raise their degree of optimism and wellbeing. Keywords : Gratitude, Hope, Forgiveness, Psychology, Optimism, Wellbeing.

Promoting Equity, Diversity, and Inclusion in Healthcare: An Example of the COVID-19 Pandemic

Healthcare systems must embody equity, diversity, and inclusion (EDI) and, in the event of unfairness, appropriate policies / countermeasures should be enacted. The healthcare system response to the COVID-19 pandemic not only highlighted how socioeconomic disparities affect mortality risk but also posed significant challenges to the successful practice of EDI in healthcare. In light of this, this article was written to provide an overview of EDI, analyze the international efforts to promote it, and suggest strategies for promoting EDI in infectious disease healthcare using COVID-19 as an example. In healthcare settings, equity centers on ensuring patients receive fair treatment regardless of race, gender, age, or socioeconomic status; diversity centers on healthcare providers understanding the uniqueness of patients from different cultural backgrounds and the health barriers they face; and inclusion centers on ensuring patients are treated with respect and given the attention they deserve. During pandemics, social determinants of health (SDOH) greatly impact patient health outcomes and hinder the practice of EDI. Reflecting on the impact of COVID-19, healthcare systems can actively apply EDI in clinical practice to provide to all patients equitable access to healthcare opportunities and outcomes. Practical strategies include establishing EDI committees within healthcare systems, monitoring relevant data, conducting staff training, and continuously addressing the SDOH and needs of marginalized groups to achieve EDI in healthcare.

Impact of COVID-19 on children diagnosed with autism spectrum disorder living in the rural regions of Arizona.

Impact of COVID-19 on children diagnosed with autism spectrum disorder living in the rural regions of Arizona.

Impact of COVID-19 led transition of work culture and travel to work patterns on society and environment in Delhi

Globally, COVID-19 has led to changes in daily lifestyle and travel behavior. There was a shift from in-person physical jobs to work-from-home culture, even for those jobs that required in-person presence at the job location. However, this was not true for everyone, and a majority continued to travel to work. The limited capacity of public transport services and the fear of exposure to the virus restrained people from practicing their conventional mobility choices. We explore the impact of COVID-19 on the nature of jobs and related changes in work travel patterns by population groups for Delhi using in-person surveys conducted during 2021 in six localities of Delhi. We also estimated the short- and long-term impacts of altered behavior on expenditures and equivalent CO2 emissions.As per the analysis, lower income groups, having no vehicles, with lesser qualifications, and employed as daily wagers, had limited capacity to change to work-from-home during COVID-19. We observed an increased dependency on personal motorized vehicles, leading to increased expenditures and reduced affordability. Adopting work-from-home during COVID-19 helped reduce equivalent CO2 emissions per working member by 39%. However, as the work at the site resumes, the emissions are expected to increase. The study shows that COVID-19 led to short-term benefits, but in the long term, the externalities will likely increase. Working from home during the pandemic provides short-term benefits; the social benefits are not equally distributed, and the transport emissions shall increase in the long term.

The Bidirectional Association Between Metabolic Syndrome and Long-COVID-19.

The rapid global spread of a new coronavirus disease known as COVID-19has led to a significant increase in mortality rates, resulting in an unprecedented worldwide pandemic. The impact of COVID-19, particularly its long-term effects, has also had a profound effect on the health and well-being of individuals.Metabolic syndrome increases the risk of heart and brain diseases, presenting a significant danger to human well-being. The prognosis of long COVID and the progression of metabolic syndrome interact with each other, but there is currently a lack of systematic reports.In this paper, the pathogenesis, related treatment and prognosis of long COVID and metabolic syndrome are systematically reviewed.

Impact of the COVID-19 pandemic on maternal, neonatal and child health service utilisation, delivery and health outcomes in Gauteng province, South Africa: an interrupted time series (ITS) analysis.

Gauteng was one of the provinces in South Africa most hit by COVID-19. However, there has been no assessment of the pandemic's impact on essential maternal, neonatal and child health (MNCH) services in Gauteng, for planning against future emergencies. This study sought to assess the impact of the COVID-19 pandemic on essential MNCH service utilisation, delivery and health outcomes in Gauteng province. We employed a quasi-experimental interrupted time series (ITS) study design, using the District Health Information System (DHIS) data set to evaluate the impact of COVID-19 on eight key MNCH indicators between March 2019 to February 2021. Using Stata V.17.0 and 5% alpha, a segmented linear regression (ITS) model quantified the trends of the indicators before COVID-19 (March 2019 to February 2020) (β1), the immediate change in level due to the March 2020 lockdown (β2), the post-lockdown (March 2020 to February 2021) trend (β4) and the change in gradient from before to after the lockdown (β3). COVID-19 lockdown exerted a significant decline in primary healthcare headcount<5 years (n) (β2= -60 106.9 (95% CI, -116 710.4; -3503.3), p=0.039); and postnatal care visits within 6 days (rate) (β2=-8.2 (95% CI, -12.4; -4.1), p=0.001). Antenatal care first visits before 20 weeks (rate) declined during COVID-19 (β3=-0.4 (95% CI, -0.7; -0.1), p=0.013) compared with the pre-COVID-19 period. COVID-19 adverse effects on service delivery (measles second dose coverage and fully immunised<1 year) and health outcomes (facility deaths 0-6 days, maternal mortality ratio and pneumonia case fatality<1 year) were insignificant. While some indicators post-lockdown attempted to recover, others deteriorated. In Gauteng province, the COVID-19 pandemic significantly disrupted essential MNCH service utilisation, particularly during the March 2020 lockdown. The mechanism of MNCH service disruption by COVID-19 was induced by both supply and demand services. It is imperative to strike a balance between maintaining routine healthcare services and managing an outbreak.

Assessing the impact of COVID-19 on HIV care cascade for people living with HIV in Ethiopia: a retrospective longitudinal study.

The study aimed to investigate the impact of COVID-19 on the cascade of HIV care for people living with HIV (PLHIV) in Ethiopia. A retrospective longitudinal study. The study was conducted in North Showa Zone, Ethiopia, from pre-COVID-19 (January 2018-December 2019) and during COVID-19 (January 2020-December 2021). We identified 61901 records from 3925 PLHIV, of which 23 848 were recorded during the pandemic. We investigated indicators from four stages of the HIV care cascade, including HIV screening and diagnosis, HIV care, HIV treatment and HIV disease progression, according to a WHO framework. The indicator changes were assessed with incidence rate ratios (IRRs). For HIV screening and diagnosis, the monthly number of HIV tests experienced a 46% decline from 2520 to 1361 since the pandemic (IRR 0.553; 95% CI 0.546 to 0.561). For HIV care, the monthly number of consultations was reduced by 49.6% (from 1582 to 798) since the pandemic (IRR 0.591; 95% CI 0.581 to 0.601). Similarly, the monthly number of viral load tests was reduced by 42.8% (IRR 0.614; 95% CI 0.581 to 0.650). For HIV treatment, the number of antiretroviral therapy (ART) initiations was reduced by 27.8% and the number of ART adherence by 52.5% since the pandemic. For HIV disease progression, the monthly number of PLHIV achieving viral suppression was reduced by 61.6%, while HIV-related deaths doubled during the pandemic. The study highlights pandemic-induced disruptions in the cascade of care for PLHIV. Targeted interventions are necessary to protect PLHIV in public health emergencies.

The Impact of COVID-19 on the peri-operative complications rate of maxillary sinus floor augmentation.

The Impact of COVID-19 on the peri-operative complications rate of maxillary sinus floor augmentation.