Optimal Power Flow (OPF) is a crucial part of the Energy Management System (EMS) as it determines individual generator outputs that minimize generation cost while satisfying transmission, generation, and system level operating constraints. OPF relies on a core EMS routine, namely state estimation, which computes system states, principally bus voltages/phase angles at the buses. However, state estimation is vulnerable to false data injection attacks in which an adversary can alter certain measurements to corrupt the estimator's solution without being detected. It is also shown that such a stealthy attack on state estimation can increase the OPF cost. However, the impact of stealthy attacks on the economic and secure operation of the system cannot be comprehensively analyzed due to the very large size of the attack space. In this paper, we present a hybrid framework that combines formal analytics with Simulink-based system modeling to investigate the feasibility of stealthy attacks and their influence on OPF in a time-efficient manner. The proposed approach is illustrated on synthetic case studies demonstrating the impact of stealthy attacks in different attack scenarios. We also evaluate the impact analysis time by running experiments on standard IEEE test cases and the results show significant scalability of the framework.