Results of experimental studies of the round air microjet interaction with a coaxial hydrogen jet at its combustion for supersonic speed jets efflux are presented in this work. It is revealed that combustion of the coaxial hydrogen jet with growth of its speed efflux is accompanied by all scenarios, observed at study of the round and plane hydrogen microjets diffusion combustion. However, “bottleneck flame region” undergoes considerable geometrical deformations because of specifics of a flame of a coaxial jet. It is shown that “bottleneck flame region” is transformed from Y-shaped to spherical shape in the activity of growth of a coaxial jet speed efflux. It is found that a round air microjet interaction with a coaxial hydrogen jet at its combustion is accompanied by several new phenomena: existence of cone-shaped area a coaxial jet combustion near a nozzle exit; existence of small-scale supersonic cells on a resultant flame; absence of the hydrogen combustion efflux from combustion region of a coaxial jet near nozzle exit; flame-out from combustion region of a coaxial jet near nozzle exit that leads to hydrogen ignition downstream, its intensive combustion and sharp acoustic noise occurrence; existence of a turbulent flame, to its separation from a nozzle exit and transition to supersonic combustion of a resultant jet.