Human Body Research Articles

Application of a new brine of sprouted grains for delicatessen products from horse meat, beef, and pork

The main task of the meat processing industry is to produce meat products as the primary source of animal protein that ensures the vital activity of the human body in the necessary volumes, high quality, and a diverse assortment. Providing the population with high-quality food products that are biologically complete, balanced in the composition of the primary nutrients, and enriched with target physiologically active components is one of the most priority scientific and technical problems to be solved. In this regard, a recipe for a new brine from sprouted grains for delicatessen products from horse meat, beef, and pork was developed. The composition of the new brine includes flavoring and aromatic ingredients, juice of sprouted grains, and juices of raw vegetable materials. The viscosity of horse meat, beef, and pork during massaging was studied. Thermodynamic parameters such as water activity and moisture binding energy of horse meat, beef, and pork using a new brine were studied. The data analysis shows that the values of the “aw” indicator and the moisture binding energy in the experimental samples of meat products are higher than in the control samples. Studies have found that with an increase in the activity of water and the moisture binding energy, the tenderness of finished delicatessen meat products with a new brine increases. As a result, it was found that the maximum amount of brine in horse meat is retained at 160 minutes of continuous massaging, in beef – at 130 minutes, in pork – at 120 minutes of mechanical processing.

Genetic and Digital Discrimination in Labor Law: Problem Statement

The last few decades have been characterized by the most active development of medicine and genetics, leading to the emergence of new knowledge about the functioning of the human body. The identification of a genetic predisposition to the development of certain diseases requires a rethink of traditional approaches to the use of employee personal data, labor protection, and the balance of public and private interests in labor legislation. This article analyzes approaches to determining the legal nature of genetic information, identifies possible areas of restriction of workers’ rights depending on the identification of hereditary predisposition to certain diseases, draws a line between discrimination based on genetic characteristics and differentiation. In the context of the active digitalization of personnel processes, the risks of possible digital discrimination in the selection and evaluation of employees using artificial intelligence technologies are noted.

Basketball Sports Posture Recognition Technology Based on Improved Graph Convolutional Neural Network

Basketball has rapidly developed in recent years. Analysis of various moves in basketball can provide technical references for professional players and assist referees in judging games. Traditional technology can no longer provide modern basketball players with theoretical support. Therefore, using intelligent methods to recognize human body postures in basketball was a relatively innovative approach. To be able to recognize the basketball sports posture of players more accurately, the experiment proposes a basketball stance recognition model based on enhanced graph convolutional networks (GCN), that is, the basketball stance recognition model based on enhanced GCN and spatial temporal graph convolutional network (ST-GCN) model. This model combines the respective advantages of the GCN and temporal convolutional network and can handle graph-structured data with time-series relationships. The ST-GCN can be further deduced by realizing the convolution operation of the graph structure and establishing a spatiotemporal graph convolution model for the posture sequence of a person’s body. A dataset of technical basketball actions is constructed to verify the effectiveness of the ST-GCN model. The final experimental findings indicated that the final recognition accuracy of the ST-GCN model for basketball postures was approximately 95.58%, whereas the final recognition accuracy of the long short term memory + multiview re-observation skeleton action recognition (LSTM+MV+AC) model was about 93.65%.

Functional Hydrogels Promote Vegetable Growth in Cadmium-Contaminated Soil.

Over the years, the concentration of cadmium in soil has increased due to industrialization. Cadmium in the soil enters the human body through plant accumulation, seriously endangering human health. In the current study, two types of hydrogels were successfully synthesized using a free radical polymerization method: an ion-type hydrogel referred to as DMAPAA (N-(3-(Dimethyl amino) propyl) acrylamide)/DMAPAAQ (N,N-Dimethyl amino propyl acrylamide, methyl chloride quaternary) and a non-ion-type hydrogel known as DMAA (N,N-Dimethylacrylamide). In the experiment carried out in this study, the ion-type hydrogel DMAPAA/DMAPAAQ was introduced to cadmium-contaminated soil for vegetable cultivation. The study found that at cadmium levels of 0 and 2 mg/kg in soil, when exposed to a pH 2 solution, cadmium wasn't detected in the filtrate using ICP. As the amount of cadmium increased to 500 mg/kg, hydrogel addition gradually reduced the filtrate cadmium concentration. Notably, the use of the 4% hydrogel resulted in 0 mg/L of cadmium. For the 0% hydrogel, vegetable cadmium absorption was determined to be 0.07 mg/g, contrasting with 0.03 mg/g for the 4% hydrogel. The DMAPAA/DMAPAAQ hydrogel significantly boosts vegetable growth by efficiently absorbing nitrate ions through ion exchange, releasing them for plant uptake. In contrast, the DMAA hydrogel, used as a control, does not enhance plant growth despite its water absorption properties. In summary, the composite hydrogel shows great potential for enhancing vegetable yield and immobilizing heavy metals in soil.

Physiological and hygienic assessment of a multilayer set of personal protective equipment against low temperatures made using membrane materials

Introduction. Advanced personal protective equipment (PPE) against low temperatures is a high–tech product created using the latest achievements of science, design designs, ergonomic, aesthetic solutions that determine its thermal protection properties. The use of membrane materials in PPE from low temperatures allows them to combine low weight and high thermal protection properties, low air permeability and sufficient vapor permeability necessary to ensure heat and moisture exchange between humans and the environment. The study aims to determine the thermal protection properties of various sets of multilayer workwear and indicators of heat and moisture exchange of volunteers when modeling professional activity at low air temperature. Materials and methods. The authors have conducted a study in a microclimatic chamber with the participation of six practically healthy male volunteers. The researchers have determined the thermal protection properties of multilayer workwear of various configurations in accordance with GOST R 12.4.185-99 and MUK 4.3.1894-04. As test samples, they have used pipes of three different configurations to protect against low temperatures, wind, water, general industrial pollution and mechanical influences, as well as short-term exposure to open fire. The assessment of heat and moisture exchange indicators of various PPE configurations was carried out by specialists when modeling work activities with measurements of the relative humidity level in the layers of the kits and the level of accumulated moisture in each element of the PPE. Results. The authors have determined the values of thermal insulation of the studied materials and the scope of their application. To assess heat and moisture exchange, two samples of PPE were selected, made using membrane and cotton fabrics with similar thermal insulation values. The analysis of the results of studies of moisture exchange indicators showed a slightly lower efficiency of moisture evaporation of the control sample. The indicator of the relative humidity of the air under the shelter space and between the layers of the package of materials and clothing has shown its informative significance for assessing the effectiveness of moisture transfer from the surface of the human body to the environment. Conclusion. The results of a physiological and hygienic assessment of a set of multilayer clothing made of membrane materials have shown that various combinations of its constituent elements make it possible to create kits that provide adequate protection for an employee in a wide range of air temperatures and wind speeds. The use of membrane materials in combination with structural elements (ventilation openings) provides a more efficient transfer of moisture from the skin surface to the external environment, as evidenced by the values of the relative humidity index of the air under the clothing space and between the layers of clothing. Ethics. The study was approved by the local Ethical committee of the Izmerov Research Institute of Occupational Health (Minutes of the meeting No. 6 dated 07/20/12)

ENTEROCOCCUS FAECALIS AS AN ETIOLOGICAL FACTOR OF PURULENT PROCESSES IN SURGICAL PATIENTS: ANALYSIS OF BACTERIOLOGICAL RESEARCH RESULTS

Introduction. Opportunistic infections are often caused by microorganisms that are part of the normal human body microflora. Studying the role of microbiota in infectious pathology and the mechanisms of interaction between opportunistic microorganisms in microbial associations is crucial. Enterococcus faecalis is one such microorganism found in bacterial associations. The purpose of this study was to investigate the frequency of detecting E. faecalis in monoculture and as part of associations, the qualitative and quantitative composition of these associations, and the analysis of the variability in the pathogen’s susceptibility to antibiotics. Results and discussion. Out of 123 samples studied, Enterococcus bacteria were cultured in 38 cases, accounting for 30.9%. E. faecalis was isolated in monoculture in only 24.2% of all cultures of this species. Moreover, it was isolated in clinically significant concentrations (≥105 bacterial cells per 1 ml of the studied material) in only four out of eight cases. There is a difference in the susceptibility of cultures for groups of isolates where the concentration of microorganisms in the test material is <105 and ≥105 microbial cells per 1 ml. Conclusion. E. faecalis was present in 26.8% of isolates obtained from patients in the surgical department with purulent-inflammatory diseases. E. faecalis is mainly found in microbial associations. The susceptibility of E. faecalis to most of the antibiotics used in the study is higher in the group of isolates where this species of microorganism was present in concentrations equal to or higher than 105 microbial cells per 1 ml of the test material.

A Self‐Healing Solid‐State Ion‐Conductive Elastomer with High Mechanical Robustness and High Conductivity for Soft Ionotronics

AbstractFlexible and stretchable ion‐conductive elastomers have shown promising applications in wearable flexible sensor devices, biopotential detection, electroluminescent devices, and other areas. However, the currently employed gel‐based ion‐conductive materials encounter issues such as solvent volatilization or leakage. Herein, there is an urgent requirement to develop a solid‐state ionic conductor material that is both safe and reliable, free from issues of liquid leakage. Here, the study reports a solid‐state ion‐conductive elastomer with excellent mechanical properties and high ionic conductivity based on a synergistic strategy of multiple interaction forces. The solid‐state ion−conductive elastomer exhibits high ionic conductivity (1.42 × 10−4 S cm−1 at 25 °C), superior stretchability (≈1550% elongation) and strength (1.48 MPa). Moreover, the solid‐state ion‐conductive elastomer exhibits high resilience and possesses excellent self‐healing ability. The wearable sensor, prepared based on the solid‐state ion‐conductive elastomer with excellent comprehensive performance, not only demonstrates high strain sensitivity but also captures high‐quality epidermal biopotential signals from the human body in biopotential detection. Additionally, the solid‐state ion‐conductive elastomer can serve as an electrode in ionic electroluminescent devices for human wearable applications. It is believed that the solid‐state ion‐conductive elastomer can provide novel opportunities for the advancement of wearable devices and soft ionotronics.

POSSIBILITIES OF OBTAINING AND VALORIZING DIETARY FIBERS IN THE CONTEXT OF THE CIRCULAR BIOECONOMY

This article aimed to review the recent literature on the characterization of dietary fibers and their role in the human body, focusing on the methods of extraction of dietary fibers from agro-food waste as well as their use in various areas of the food industry. Dietary fibers are biologically active substances with beneficial effects on human health. Soluble dietary fiber is involved in reducing cholesterol levels and blood sugar levels, while insoluble dietary fiber helps regulate intestinal transit and maintain colon health. It would be useful to identify the extraction procedures and characterization of dietary fibers from agro-food waste. Fruit waste contains relevant amounts of bioactive compounds, such as: phenolic acids, flavonoids, lignins, carotenoids, etc. In addition, fruit waste contains significant amounts of dietary fiber with nutraceutical important activities, such as modulating the intestinal microbiota, lowering cholesterol, triglycerides and glycemic load in the blood. Hence, obtaining dietary fiber from agro-industrial waste can solve a number of economic and environmental problems that aim reducing waste, increasing the sustainability and profitability of companies in the Republic of Moldova. Dietary fiber can be used in various types of food, such as products of bakery and confectionery, meat, dairy products, and pasta. They can be used as stabilizers with an impact on food texture or ingredients with low caloric value, partially replacing caloric constituents such as fats, starch or sugars. Another important property is the prebiotic effect of dietary fibers. This property is determined by the fact that dietary fibers are indigestible or poorly digestible and are fermented selectively by intestinal microbiota, conferring health benefits to the host.

LONG-TERM EFFECTS OF COVID-19

The COVID-19 pandemic has been a defining global event, impacting nearly every aspect of life worldwide. This paper presents a review of the long-term effects of COVID-19, focusing on the impacts on people’s physical and mental health. It synthesizes current knowledge from different studies, articles, analyses, and case reports to provide a comprehensive understanding of the prolonged physical, psychological and socioeconomic consequences of COVID-19. The virus has prolonged effects on various organ systems in human body especially in individuals who experienced severe cases or complications, as well as profound psychological impact. Efforts to address the physical and mental consequences of COVID-19 require a comprehensive approach involving healthcare professionals, mental health providers, policymakers, community organizations, and individuals themselves.

Metabolic Modernities: Digestion, Energy Transformations, and the Making and Unmaking of the World in Early Soviet Literature

AbstractEarly Soviet society featured clear nutrition guidelines and a robust plan for streamlined logistics in food processing, distribution, and consumption, all of which was aimed at building a stronger state through a virtuous transformation of calories into labor power. Such rhetoric appeared even in children’s illustrated books, such as Vladimir Maiakovskii and Nikolai Kupreianov’s Story of Petia, Fat Boy, and of Sima, Who is Skinny (1926). This paper shows how in the 1920s authors such as Viktor Shklovskii and Iurii Olesha turned that rhetoric on its head and pushed back against the early Soviet obsession with planning and mastering nature and the human body by employing metaphors of food, digestion, and agriculture. In Shklovskii’s memoirs A Sentimental Journey (1923) and Knight’s Move (1923) and Olesha’s novel Envy (1927), the October Revolution itself emerges as a metabolic process on a vast scale: prerevolutionary aesthetic threads, motifs, and concepts are broken down and processed, reassembled, and repurposed into a seemingly new society and worldview, in which the individual original components are still recognizable.

A Critical View on Virudha Aahar: Dietic Incompatibility

The three Upstambha (Aahar, Swapna, and Brahmchraya) that describe in the Ayurvedic Samhitas. These three Upstambha hold the body. The body gains strength, firmness, and Varna by carefully using these three pillars. Aahar, the first Upstambha, is helpful for keeping the body in a healthy state. However, people are now consuming improper foods in the wrong combinations. Certain drugs and dietary combinations that have traits in opposition to body elements may decrease the body's immunity. Such types of foods are referred to as Virudha Aahar in old Ayurvedic texts. This article describes how individuals nowadays consume Virudha Aahar and how it has adverse effects on the human health. What impacts do they have on each physiological system of human body?

Review of the Potential Role of Ascorbate in the Prevention and Treatment of Gynecological Cancers.

Ascorbate (vitamin C) is an essential vitamin for the human body and participates in various physiological processes as an important coenzyme and antioxidant. Furthermore, the role of ascorbate in the prevention and treatment of cancer including gynecological cancer has gained much more interest recently. The bioavailability and certain biological functions of ascorbate are distinct in males versus females due to differences in lean body mass, sex hormones, and lifestyle factors. Despite epidemiological evidence that ascorbate-rich foods and ascorbate plasma concentrations are inversely related to cancer risk, ascorbate has not demonstrated a significant protective effect in patients with gynecological cancers. Adequate ascorbate intake may have the potential to reduce the risk of human papillomavirus (HPV) infection and high-risk HPV persistence status. High-dose ascorbate exerts antitumor activity and synergizes with chemotherapeutic agents in preclinical cancer models of gynecological cancer. In this review, we provide evidence for the biological activity of ascorbate in females and discuss the potential role of ascorbate in the prevention and treatment of ovarian, endometrial, and cervical cancers.

Safety Improvements for High-Speed Planing Craft Occupants: A Systematic Review

Moving fast by high-speed planing craft (HSPC) is advantageous for some special missions, though it causes severe hull vibrations and shocks that can transfer to the human body and increase health and comfort risks. This study reviews the current safety standards to avoid human safety risks affected by whole-body vibrations (WBVs), as well as the safety status of HSPC occupants. In addition, the efficiency of motion-reduction devices (trim tab and interceptor) and shock/vibration-mitigation devices (shock-mitigation seat) in improving the safety of HSPC occupants is examined according to existing documents. The research methodology was based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRIS-MA) method, and published papers in the Scholar, Scopus, and Web of Science databases were analyzed. Because most of these publications are academic research, issues of bias in the eligible publications were not of particular interest. During this systematic review, many gaps and challenges in current information on safety improvement devices were found that need to be addressed in future studies, such as a lack of information on motion-reduction devices and shock-mitigation seat performance in reducing lateral and fore-and-aft motions. Referring to these gaps and challenges can be valuable as a suggestion to improve current knowledge in research and reduce safety risks.

Development of Innovative Forms and Methods in Physical Culture as a Means to Increase Student Motivation for an Active Lifestyle

The article presents an analysis of innovative forms and methods of physical education that would help increase the interest of students in leading an active lifestyle. Its goal is to demonstrate the results of research activities related to the latest and most relevant forms and methods of physical education, as well as to highlight their potential application in the practice of teachers to increase the level of student motivation. The study employed various scientific methods, including analysis, synthesis, induction, deduction, comparison, and generalisation. Physical activity has been shown to have positive effects on the human body, in particular helping to maintain cardiovascular health, musculoskeletal health, weight control, increasing energy and vitality, reducing stress and improving mental health, increasing brain activity and reducing the risk of developing chronic diseases.The analysis of the source material on the topic of the study revealed that increasing motivation for physical education is a relevant but underdeveloped issue. To address this, we constructed a table that outlines innovative forms and methods of physical education and their impact on students’ motivation to lead an active lifestyle. We have identified several innovative forms and methods of physical education that could increase students’ motivation for a healthy lifestyle. These include the use of virtual reality (VR), sensory technologies, game technologies, interactive simulators, multimedia teaching methods, interactive applications for a healthy lifestyle, training with celebrities, online training, training using the wind tunnel, and excursions. The introduction of virtual reality elements, as presented at CES 2019 in Las Vegas, is an interesting development. We believe that empirical research into the detailed study of the practical component of innovative forms and methods of physical education, which would help to increase the motivation of students at different levels to adopt a healthy lifestyle, is promising.

The catalytic hydro-dechlorination of 2, 4, 4’ trichlorobiphenyl at mild temperatures and atmospheric pressure

ABSTRACT Polychlorinated biphenyls (PCBs), including all 209 congeners, are designated as persistent organic pollutants (POPs) due to their high toxicity and bioaccumulation in human bodies and the ecosystem. The need for PCB remediation still remains long after their production ban. In this study, a catalytic hydro-dechlorination (HDC) method was employed to dechlorinate 2,4,4’-trichlorobiphenyl (PCB 28), a congener found ubiquitously in multiple environmental media. The HDC of PCB 28 was experimentally studied at mild temperatures viz. ~20, 50, and ~ 77°C and atmospheric pressure. Et3N (triethylamine) was added as a co-catalyst. The dechlorination rates increased with temperature as well as Et3N dosage, and the HDC pathway was hypothesized based on the product and intermediates observed. The less chlorinated intermediates suggested that the position of the chlorine strongly impacted HDC rates, and the preference of HDC at para positions can be orders of magnitudes higher than the ortho. The activation energy, was estimated in the range of 12.4-13.9 kJ/mole, indicating a diffusion-controlled HDC system. Implication Statement The remediation need for polychlorinated biphenyls (PCBs) still remains long after their production ban around the world. The development of low cost methods is highly desirable, especially for developing countries, in response to the Stockholm Convention. In this study, the dechorination of a ubiquitously present PCB congener was studied using a catalytic hydro-dechlorination (HDC) method in low temperatures up to ~ 77°C and was able to achieve near 100% dechlorination in six hours. Results indicated that the HDC process can be performed under mild temperatures and atmospheric conditions and can be a potential solution to real world PCB contamination issues.

History of the use of chemical weapons for military purposes and the possibility of their current use

Throughout the history of mankind there have been many wars of both local character and large-scale wars. At the heart of military actions necessarily lies the use of weapons, one type of which is chemical. Chemical weapons, the basis of which are diverse in their effect on the body and chemical composition of poisonous substances, began to be used for military purposes during World War I, namely, the first use occurred on April 22, 1915 in Belgium near the city of Ypres. Germany used gas cylinders filled with chlorine in this attack. The man who created this weapon was German chemist Fritz Haber, who became known as the "father of chemical weapons". Since that time, scientists from different countries began to actively study the effect of poisonous substances on the human body, synthesize their new types, as well as search for reliable means of protection against its effects. Throughout history, attempts have been made to ban the use of chemical weapons. In particular, after the end of the First World War, the Geneva Protocol was adopted in 1925, prohibiting the use of asphyxiating, poisonous or other similar gases in war. However, this agreement failed to limit the use of poisonous substances, which led to their further use, mainly in localized wars. Much work on the prohibition and destruction of chemical weapons belongs to the Organization for the Prohibition of Chemical Weapons, established in 1997 after the adoption of the Convention on the Prohibition of the Development, Production, Stockpiling and Use of Chemical Weapons and on Their Destruction in 1993. The purpose of this paper is to summarize the history of chemical weapons for military purposes, as well as to study the activities for their prohibition. Literary data of recent years on the history of creation, use of chemical weapons and international legal agreements on their prohibition and destruction, the main types of toxic substances, means of protection against their effects are analyzed. Conclusions are made about the possibilities of chemical weapons use at present.

Recovery and relaxation of the body after physical activity in sports

The article discusses varieties and variants of relaxation techniques that must be used after intense loads. The concept of "relaxation", the understanding of its role in physical education to support health, harmonious development of student youth, mental, mental and physical health has been extensively researched. Also presented are modern diagnostic systems and hardware for the recovery of athletes' bodies, which increase sports performance and maintain physical and mental health. The main direction of physical education is the formation of a healthy, mentally prepared, socially active, morally stable, physically improved and prepared person for the future profession. The human body is a complex system that monitors and regulates its own condition. At rest and during light loads, all processes take place at a normal pace. But the load that affects the body forces it to use reserve energy reserves, which ensures the normal functioning of the body during heavy exercises. After intense training, it is very important to give the body the opportunity to rest before the next exercise. Therefore, the use of various restorative means and modern methods of relaxation after training and competitive loads is considered as an integral part of physical activities. Recovery from exercise is important for improving athletic performance and preventing injury. Physical activity plays an important role in our lives. They help us strengthen muscles, increase endurance, and improve overall fitness. However, after intense training, our bodies need to recover. Insufficient rest can lead to fatigue, injury, and decreased training performance.

ADAPTATION MECHANISMS ARE USED BY THE BODY OF STUDENTS FOR RECOVERY AFTER PHYSICAL EXERTION

The study of the morphofunctional features of the body's adaptation to constantly changing living conditions is considered one of the most important problems of biology and medicine today. The effectiveness of adaptive processes in the body is the primary basis of good health and high productivity. Therefore, the resolution of the unexplained issues of this problem is important for the prevention and treatment of diseases, the search for effective rehabilitation measures. Knowledge of the laws of adaptation of the human body (athlete) to physical exertion is an objective prerequisite for the effective use of physical exercises in the rationalization of physical training aimed at preserving and strengthening people's health, increasing their work capacity, and implementing a genetically programmed longevity program. The defining function of muscle activity is the function of active adaptation of the body to constantly changing environmental conditions. The ultimate goal of this active adjustment is to maintain internal constancy environment, expanding the homeostatic limits of individual physiological constants, ensuring highly productive activity. The most effective means of adaptive change of a person's own nature is systematic physical training. High perfection of mechanisms of neurohumoral regulation functions; optimization of inter-system and intra-system connections; high development of self-regulation in the activity of functional systems. There is a direct relationship between the power of work and the perfection of mechanisms of regulation of functions: the more intensively the body functions under conditions of physical exertion, the greater the tension of regulatory systems; the more perfectly function regulation systems function, the body will be able to develop greater work capacity [1].

Форми медичного контролю на заняттях силової направленості

Medical control is a scientific and practical branch of medicine that studies the issues of physical development, functional state, and health of the human body during physical exercises and sports. The purpose of medical control is to promote the effectiveness of the physical education process in every way, the correct use of physical culture tools. Medical control is a mandatory condition for injury prevention, preservation of human health, longevity, and creative activity. The main tasks of medical control: determining the state of health and solving issues of admission to classes in various forms and groups; carrying out medical control at physical education and sports classes; diagnostics of the functional state; assessment of physical development and identification of diseases and injuries; medical provision of competitions; agitation and promotion of physical culture among the population. Forms of medical control: regular medical examinations and control of persons engaged in physical exercises and sports; medical and pedagogical observations of people who are engaged in classes and competitions; sanitary and hygienic control over the places and conditions of classes; medical and sanitary provision of mass health and sports events (in sports camps and at educational and training meetings);prevention of sports injuries and diseases; sanitary and educational work and promotion of physical culture, sports, a healthier lifestyle. Physical development is assessed using anthropometric measurements, as well as the method of questioning and external examination. Anthropometric measurements make it possible to determine the level and features of physical development, the degree of conformity to gender and age.

Evaluation of High-Dimensional Data Classification for Skin Malignancy Detection Using DL-Based Techniques

Skin cancer can be detected through visual screening and skin analysis based on the biopsy and pathological state of the human body. The survival rate of cancer patients is low, and millions of people are diagnosed annually. By determining the different comparative analyses, the skin malignancy classification is evaluated. Using the Isomap with the vision transformer, we analyze the high-dimensional images with dimensionality reduction. Skin cancer can present with severe cases and life-threatening symptoms. Overall performance evaluation and classification tend to improve the accuracy of the high-dimensional skin lesion dataset when completed. In deep learning methodologies, the distinct phases of skin malignancy classification are determined by its accuracy, specificity, F1 recall, and sensitivity while implementing the classification methodology. A nonlinear dimensionality reduction technique called Isomap preserves the data’s underlying nonlinear relationships intact. This is essential for the categorization of skin malignancies, as the features that separate malignant from benign skin lesions may not be linearly separable. Isomap decreases the data’s complexity while maintaining its essential characteristics, making it simpler to analyze and explain the findings. High-dimensional datasets for skin lesions have been evaluated and classified more effectively when evaluated and classified using Isomap with the vision transformer.