Hospital Of Zhengzhou Research Articles

Posterior sub-tenon’s injection of triamcinolone acetonide in the treatment of optic disc vasculitis

Objective To evaluate the efficacy of posterior sub-tenon’s injection of triamcinolone acetonide in the treatment of optic disc vasculitis. Methods The clinical data of 60 eyes of 60 patients with optic disc vasculitis from May 2016 to May 2019 in the Seventh People’s Hospital of Zhengzhou were retrospectively analyzed. Triamcinolone acetonide 40 mg/0.5 ml was injected into Tenon’s capsule with a self-made gauge 6 lacrimal irrigation needle, and compound Xueshuantong and energy mixture were infused intravenously, compound anisodine injection was injected subcutaneously beside superficial temporal artery, methylcobalamin, citicoline and compound vitamin B were taken orally. All patients were followed up for 6-18 months. Results All 60 cases were cured within 6 to 18 months after treatment. The visual acuity were improved and the shape of macular fovea were restored, macular edema were alleviated. Conclusion Posterior sub-tenon’s injection of triamcinolone acetonide in the treatment of optic disc vasculitis is safe, effective, simple and inexpensive. Key words: Vasculitis, optic disc; Triamcinolone acetonide, injection, sub-tenon’s posterior; Efficacy, clinical

Prevalence of deep venous thrombosis in chronic refractory wounds and its influencing factors

Objective: To investigate the incidence and risk factors of lower extremities deep venous thrombosis (DVT) in patients with chronic refractory wounds (chronic wounds). Methods: A retrospective analysis of 722 cases of chronic wounds admitted to the First People's Hospital of Zhengzhou from January 1, 2015 to December 31, 2018 was carried out, and clinical data such as gender, age, wound involves the lower extremities, wound type, duration of wound, D-dimer level and complicated diabetes, hypertension, coronary heart disease, cerebral infarction, pneumonia and sepsis/septic shock were collected. The patients were divided into DVT group and non-DVT group according to the color ultrasound test. Multivariate binary logistic regression analysis was used to screen the independent risk factors of DVT in patients with chronic wounds. Results: There were 55 (7.6%) patients in DVT group, of which 44(80.0%) were diagnosed as chronic DVT by conventional lower extremities venous color ultrasound screening at admission, and the remaining 11(20.0%) were newly diagnosed during hospitalization. There were no significant differences in gender, wound involves the lower extremities, duration of wound, complicated diabetes and hypertension between DVT group and non-DVT group (all P>0.05); and the differences were statistically significant in age, wound type, D-dimer level, complicated coronary heart disease, cerebral infarction, pneumonia and sepsis/septic shock (all P<0.05). Multivariate binary logistic regression analysis showed age [OR=2.260 (95%CI: 1.584-3.224)], D-dimer level [OR=14.201 (95%CI: 6.101-33.055)], complicated coronary heart disease [OR=2.731 (95%CI: 1.210-6.162)] and sepsis/septic shock [OR=3.170 (95%CI: 1.115-9.016)] were independent risk factors for DVT (all P<0.05). Conclusion: Chronic wounds patients have a higher incidence of DVT, most of which are chronic DVT, and age, D-dimer level, complicated coronary heart disease and sepsis/septic shock are independent risk factors for DVT in chronic wounds.

Effects of yoga exercise on exercise capacity, anxiety and depression in patients with acute myocardial infarction

Objective To investigate the effects of yoga exercise on exercise capacity, anxiety and depression in patients with acute myocardial infarction. Methods 75 patients with emergency PCI in Cardiology Department of a ClassⅢ Grade A hospital in Zhengzhou from January to December in 2017 were seclected as subjects and randomly divided into control group (n=37) and intervention group (n=38) by convenient sampling. The control group received routine care, including health education, psychological care, risk factor control, medication and routine exercise education; the intervention group implemented a yoga-based exercise based on the control group. The incidence of adverse cardiac events after intervention was compared between the two groups. Before and after the intervention, the 6-min walk test (6MWT) , the Self-rating Anxiety Scale (SAS) , and the Self-rating Depression Scale (SDS) were used to evaluate the two groups of patients. Results Within 6 months of interventional therapy, 11 patients in the control group developed angina pectoris, and 3 patients in the intervention group developed angina pectoris. The difference between the two groups was statistically significant (P<0.05) . The differences of 6MWT distances between the two groups at 1st, 3rd, and 6th months after discharge were statistically significant (P<0.05) . The differences of SAS scores between the two groups at 1st, 3rd, and 6th months after discharge were statistically significant (P<0.05) . There were significant differences in SDS scores between the two groups at discharge, and 1, 3, and 6 months after discharge (P<0.05) . Conclusions Yoga-based exercise program can improve the exercise capacity of patients with acute myocardial infarction and relieve anxiety and depression. Key words: Yoga; Acute; Acute myocardial infarction; Percutaneous coronary ntervention; Exercise rehabilitation

Status quo of self-disclosure in patients with stroke and its influencing factors

Objective To explore the status quo of self-disclosure in patients with stroke and analyze its influencing factors. Methods In this cross-sectional study, totally 248 patients with stroke admitted in Neurological Wards of a ClassⅢ Grade A hospital in Zhengzhou between February and August 2019 were selected as subjects by convenient sampling, and investigated with the demographic questionnaire, Distress Disclosure Index (DDI) , Stigma Scale for Chronic Illness (SSCI) , Self-rating Depression Scale (SDS) and Perceived Social Support Scale (PSSS) . Results The SSCI score of the stroke patients was (35.56±6.26) , including 17.74% (44/248) at low levels, 74.60% (185/248) at medium levels, and 7.66% (19/248) at high levels. The total SSCI score of the stroke patients was (55.95±10.80) ; the SDS score was (56.98±9.31) ; and the PSSS score was (54.10±10.83) . Multiple linear regression analysis revealed that educational level, monthly household income per capita, stigma of chronic diseases, depression and social support were the influencing factors of self-disclosure in patients with stroke (P<0.05) , which could account for 36.6% of the total variation of self-disclosure. Conclusions The self-disclosure of stroke patients stands at a medium level and needs to be improved. Medical workers should take effective interventions to improve the self-disclosure of stroke patients and promote their physical and mental health. Key words: Cross-sectional study; Stroke; Depression; Self-disclosure; Stigma; Social support

Application of knowledge-attitude-behavior theory based health education combined with health diary in ulcerative colitis patients

Objective To explore the effects of knowledge-attitude-behavior theory based health education combined with health diary on medication adherence and quality of life in ulcerative colitis patients. Methods From February 2018 to January 2019, we selected 100 ulcerative colitis patients of Department of Gastroenterology at People's Hospital of Zhengzhou as subjects by convenience sampling. Patients were divided into control group and experimental group based on odd-even admission order, 50 cases in each group. There were 8 cases lost to follow-up due to out of touch in control group, and 4 cases withdrew from the study for various reasons in experimental group. Finally, totals of 42 cases were in control group and 46 cases were in experimental group. Control group carried out routine health education and discharge follow-up. On the basis of that, experimental group implemented knowledge-attitude-behavior theory based health education, and guided and supervised patients' health diary. The medication adherence and quality of life of patients between two groups were evaluated with the Morisky medication adherence scale and 36-item short-form health survey (SF-36) . Results Before intervention, there was no statistical difference in the scores of medication adherence patients between two groups (P>0.05) . After intervention, the score of medication adherence of experimental group was higher than that of control group with a statistical difference (P 0.05) . After intervention, the scores of bodily pain, general health status, vitality, social function, mental health of patients in experimental group were higher than those in control group with statistical differences (P 0.05) . Conclusions Knowledge-attitude-behavior theory based health education combined with health diary can improve medication adherence and quality of life of ulcerative colitis patients which has the generalization and application value. Key words: Colitis, ulcerative; Knowledge-attitude-behavior theory; Health records; Medication adherence; Quality of life

Molecular characterization of three intestinal protozoans in hospitalized children with different disease backgrounds in Zhengzhou, central China

BackgroundCryptosporidium spp. and Giardia duodenalis are major intestinal pathogens that can cause diarrheal diseases in humans, especially children. Enterocytozoon bieneusi is another parasite which can cause gastrointestinal tract disorders, with diarrhea being the main clinical symptom. However, few genetic studies of these parasites in pediatric inpatients in China have been published.MethodsTo assess the genetic characteristics and epidemiological status of these parasites, a total of 2284 fecal samples were collected from children in the pediatric departments of three hospitals in Zhengzhou, central China, and screened for these protozoans with PCR, based on the small subunit ribosomal RNA (SSU rRNA) genes of Cryptosporidium spp. and G. duodenalis and the internal transcribed spacer (ITS) of E. bieneusi.ResultsSix (0.26%), 14 (0.61%), and 27 (1.18%) of the samples were positive for Cryptosporidium spp., G. duodenalis and E. bieneusi, respectively. Of the 12 successfully sequenced G. duodenalis isolates, four were identified as assemblage A and eight as assemblage B. In subtype and multilocus genotype (MLG) analyses, C. parvum IIdA19G1 (n = 4) and two novel G. duodenalis MLGs belonging to subassemblage AII (n = 3) and BIV (n = 5) were successfully identified. The E. bieneusi isolates included genotypes D (n = 17), J (n = 2), PigEBITS7 (n = 1), BEB6 (n = 1), and CM8 (n = 1). This is the first report of C. parvum subtype IIdA19G1 in HIV-negative children and E. bieneusi genotype CM8 in humans.ConclusionsThe dominance of zoonotic C. parvum subtype IIdA19G1 indicates that this parasite is turning into zoonotic origin from human-to-human transmission. The phylogenetic analysis also revealed the zoonotic origins and anthroponotic transmission potential of G. duodenalis and E. bieneusi, suggesting more efforts must be made to minimize the threat these pathogens pose to public health.

THE CURRENT SITUATION AND INFLUENTIAL FACTORS OF FRAILTY IN ELDERLY PATIENTS WITH DIABETES IN CHINA

Patient with diabetes may increase the incidence of frailty. Frailty cause chronic inflammation and insulin resistance. The purpose of this study is to investigate the current situation of frailty and its influencing factors in elderly patients with diabetes. Totally 300 elderly patients with diabetes were selected from a tertiary hospital in Zhengzhou of China via convenience sampling method，and were investigated by self-designed general information questionnaire，TFI (Tilburg Frailty Indicator) and SDSCA(Scale of Diabetes Self-care Activities). Totally 296 valid questionnaires were collected. A total of 137 elderly patients with diabetes suffered from frailty and the prevalence was 46.3%. The mean score of total frailty was (5.26±2.87) and the scores for each dimension were as follows: physical frailty (2.79±2.08), psychological frailty (1.40±0.94) and social frailty (1.07±0.75). Multiple linear regression showed that comorbidity, self-management behavior, glycosylated hemoglobin, educational degree, polypharmacy and smoking were the major influential factors (P<0.05). The prevalence of frailty in elderly patients with diabetes was at a high level, containing different degrees of physical, psychological and social frailty. Medical staff should attach great importance to the assessment of frailty among elderly patients with diabetes, take targeted and holistic interventions timely to prevent or delay the development of frailty.

Changes and significances of vascular endothelial cadherin, procalcitonin in serum and cerebrospinal fluid of children with viral encephalitis or bacterial meningitis

Objective To investigate the changes and clinical significance of vascular endothelial (VE)-cadherin and procalcitonin (PCT) in serum and cerebrospinal fluid (CSF) of children with viral encephalitis or bacterial meningitis(BM). Methods A total of 42 cases of children with viral encephalitis(viral encephalitis group), 36 cases of children with BM(BM group), and 20 cases of children with non-nervous system injury(control group) were selected from September 2016 to June 2018 at the Third Hospital of Zhengzhou University.The serum and CSF levels of VE-cadherin and PCT levels of the 3 groups were detected by using enzyme-linked immunosorbent assay. Results The levels of VE-cadherin in the serum of viral encephalitis group, BM group and control group at the acute phase were (5.60±1.17) mg/L, (7.08±1.01) mg/L and (2.52±0.68) mg/L respectively, and the levels of VE-cadherin in CSF of viral encephalitis group, BM group and control group were (6.00±1.09) mg/L, (6.97±1.11) mg/L and(1.93±0.88) mg/L, respectively.The levels of PCT in the serum of viral encephalitis group, BM group and control group at the acute phase were (0.26±0.11) μg/L, (0.82±0.17) μg/L and (0.27±0.13) μg/L, respectively, and the levels of PCT in the CSF of viral encephalitis group, BM group and control group were (0.25±0.11) μg/L, (0.72±0.14) μg/L, (0.28±0.17) μg/L, respectively.As a result, the levels of VE-cadherin and PCT in the serum and CSF of BM group showed significant increase, compared with viral encephalitis group and control group in the acute phase(F=124.94, 163.21, 151.62, 127.37, all P 0.05). The levels of VE-cadherin in the serum of viral encephalitis group and BM group after treatment were (2.34±0.81) mg/L and (2.67±1.29) mg/L, and were(2.55±0.92) mg/L and(2.39±0.74) mg/L in the CSF.The levels of PCT in the serum of viral encephalitis group and BM group after treatment were (0.25±0.11) μg/L, (0.30±0.17) μg/L, and the levels of PCT in the CSF of viral encephalitis group and BM group were(0.22±0.10) μg/L and (0.27±0.12) μg/L.After effective treatment, the levels of VE-cadherin, PCT in serum and CSF of BM group and viral encephalitis group were almost equal, and the difference was not statistically significant(F=1.83, 0.76, 2.72, 3.89, all P>0.05). In the receiver operating characteristic (ROC) curve, the area under the ROC curve of VE-cadherin in serum and CSF was 0.896 and 0.912, and was 0.670 and 0.668 of PCT respectively. Conclusions VE-cadherin may be involved in the early stage of intracranial infection, and it may be helpful in differentiation of virus or bacterial infection with PCT.VE-cadherin has a good diagnostic value for intracranial infection. Key words: Viral encephalitis; Bacterial meningitis; Vascular endothelial cadherin; Procalcitonin

Application of diversified teaching in clinical teaching of nursing students in Infant Cardiac Surgery practice

Objective To explore the application effects of diversified teaching for nursing students in clinical practice, and provide reference for clinical nursing teaching. Methods By convenience sampling, 120 nursing students in the department of Infant Cardiac Surgery in a Class Ⅲ Grade A hospital in Zhengzhou from March 2017 to April 2018 were selected and divided into the experimental group and control group with 60 students in each group. The experimental group was given the diversified teaching approach centered by students while the control group was adopted the conventional teaching method with the teachers as the center. Upon leaving the department, the two groups were compared in terms of their results in specialized nursing theoretical examination and practical examination as well as the teaching satisfaction. Results The experimental group was higher than the control group in the specialized nursing theoretical examination and practical examination results with statistical difference (P<0.05) ; the teaching satisfaction of the experimental group was higher than that of the control group with statistical difference (P<0.05) . Conclusions Diversified teaching, compared with the conventional teacher-centered model, can more effectively improve the nursing students' initiative and activity and the quality of clinical practice teaching. Key words: Nursing education; Diversified teaching; Cardiac Surgery; Clinical practice

Nursing students' experience of participation in group resuscitation workshop: a qualitative study

Objective To explore the nursing students' experience of participation in group resuscitation workshop. Methods From July to September of 2018, 12 nursing interns in the Emergency Department of a Class Ⅲ Grade A hospital in Zhengzhou were recruited to participate in the study by purposive sampling and semi-structured interviews were conducted. The data obtained were analyzed by Colaizzi method. Results Nursing students' experience of participation in the team recovery workshop can be summarized into three themes: teamwork awareness, independent learning ability and confidence, and stress and response. Conclusions The workshop promotes nursing students' sense of teamwork and stimulates their subjective initiative and ability to learn. It is suggested that nursing clinical education workers should attach importance to the various pressures faced by students and provide support from various angles. Key words: Students, nursing; Group resuscitation; Self-initiative learning; Workshop

Construction and application of the multi-module training program of core competence for junior midwives

Objective Constructing and applying the multi-module training program for junior midwives to improve the training quality. Methods The training program was constructed according to different modules of core competence. 11 junior midwives were selected from a hospital in Zhengzhou as trainees. The training effect was evaluated. Results Their core competence has been enhanced in theory knowledge, operating skills and training satisfaction (P < 0.05). After training, the rate of episiotomy and the rate of postpartum hemorrhage were lower than before (P<0.05). Conclusion The multi-module training program can improve the core competence of junior midwives, which provides effective training method and promotes the quality of training. Key words: Midwife; Core competence; Multi-module; Training program

Eyeball development assessment following monocular congenital cataract extraction in different age infants

Objective To investigate the changes of the axial length, corneal curvature and refractive power in infants with monocular congenital cataract. Methods A retrospective cohort study was carried out.The clinical data of 105 eyes of 105 cases with monocular congenital cataract who were received cataract extraction during January 2015 to December 2017 were collected in the First Affiliated Hospital of Zhengzhou University.According to the initial operation age, the infants were assigned to 3-6 month old group, 7-12 month old group and 13-18 month old group.The patients were followed-up for 12 months.Axial length, corneal curvature and refractive power were recorded in 3, 6 and 12 months after surgery.This study followed the Declaration of Helsinki, and written informed consent was obtained from each guardian prior to any medical examination. Results The increasing value of axial length in 3-6 month old group was larger than that in 7-12 month old group, and increasing value in 7-12 month old group was larger than that in 13-18 month old group (all at P 0.05). The change value of refractive power was gradually increased as aging at 12 months after surgery (all at P<0.001). The surgical eye amplitude of change in refractive diopter was higher than healthy eye, with significant difference between them (P<0.001). Conclusions The developing process of axial length and corneal curvature are interacted and coordinated in bilateral eyes in infants who received extraction surgery of monocular congenital cataract.It is better to remove the cataract as early as possible in infants.Refraction of bilateral eyes still has a trend to myopia, and the shifting amplitude of myopic power decreases with aging. Key words: Cataract, congenital/surgery; Axial length; Corneal curvature; Refraction

Correlation between coping-adaptation level and self-consistency among molecular targeted therapy related rash patients with nonsmall-cell lung cancer

Objective To explore the correlation between coping-adaptation level and self-consistency among molecular targeted therapy related rash patients with nonsmall-cell lung cancer (NSCLC) and to analyze the influencing factors of the coping-adaptation level. Methods From June 2014 to June 2017, we selected 108 rash and NSCLC patients with molecular targeted therapy in the Third People's Hospital of Zhengzhou. The coping-adaptation and self-consistency were evaluated with the Chinese Version of Coping-adaptation Processing Scale: Short Form (CV-CAPS: SF) and Self Consistency and Congruence Scale (SCCS) . Data was analyzed statistically with the SPSS 22.0. Results Among 108 molecular targeted therapy related rash patients with NSCLC, the scores of coping-adaptation as well as self-consistency were (38.94±6.14) and (130.00±15.50) . Pearson correlation analysis showed that coping-adaptation had a positive correlation with the self-flexibility (P<0.01) , and had negative correlations with disharmony between self and experience as well as self-stiffness (P<0.01) . There were statistical differences in the scores of coping-adaptation among molecular targeted therapy related rash and NSCLC patients with different sexes, ages, educational levels, vocation, personal monthly income, reimbursement rate of medical insurance and whether to live with their children (P<0.01) . Multiple linear regression showed the influencing factors of coping-adaptation included sexes, ages, educational levels, personal monthly income (P<0.01) . Conclusions Coping-adaptation and self-consistency of molecular targeted therapy related rash patients with NSCLC need improvement with correlations between them. Medical staff should take positive and effective measures to improve cognition of patients on treatment, so as to enhance their coping-adaptation levels and self-consistency. Key words: Molecular targeted therapy; Exanthema; Coping-adaptation; Self-consistency

Clinical study of different adsorbents with dual plasma molecular adsorption system in the treatment of hepatic failure

Objective: To investigate the effects of two different sorbents(Carbon perfusion apparatus and Resin perfusion apparatus)in Double plasma molecular absorb syetem for liver failure treatment. Methods: A total of 152 cases with liver failure who were admitted to The Sixth People's Hospital of Zhengzhou, from June 2016 to May 2018 were selected and divided into DPMARS Carbon group (77 cases) and Resin group (75 cases). The two groups were observed in terms of liver function, prothrombin activity(PTA),Plasma albumin ,tumor necrosis factor alpha and interleukin-6 were detected and compared between the two groups before and after treatment. Results: ①The clinical symptoms improved in different degree in two groups, the recovery rate of Carbon cans Carbon perfusion apparatus group and Resin group separately were89.6% (69/77)、90.7% (68/75)(χ(2) = 0.048, P = 0.975), there were no statistical differences. There were no statistical differences between the two groups in untoward reactions(χ(2) = 0.235, P = 0.995), ②Compared with before treatment, TBil(t = 3.735, 3.728; P = 0.000, 0.000)、ALT(t = 5.117, 5.203; P = 0.000, 0.000)、TNF-α (t = 3.158, 3.094; P = 0.000, 0.002)、IL-6(t = 3.647, 3.559; P = 0.002, 0.003)decreased and ALB (t = 2.300, 3.065; P = 0.024, 0.003) increased significantly after treatment in both groups, and there were statistical differences. There were no signifiant differences in the changes in ALB(t = 0.316, 0.209; P = 0.657, 0.720) and PTA(t = 0.810, 0.843; P = 0.429, 0.516). ③After treatment, there were no signifiant differences in the changes in TBil、ALT、ALB、PTA、TNF-α、IL-6(t = 0.377、0.904、-1.133、-1.552、0.841、0.401; P = 0.952、0.283、0.826、0.094、0.154、0.457). Conclusion: Double plasma molecular absorb syetem is effective in treating liver failure. Carbon perfusion apparatus or Resin perfusion apparatus can be combined with Specific bilirubin adsorption column for DPMARS in clinical treatment,and their effects are similar.

Patterns of Drug-Resistant Bacteria in a General Hospital, China, 2011-2016.

Drug-resistant bacteria has been a threat to public life and property. We described the trends and changes in antibiotic resistance of important pathogens in a general hospital in Zhengzhou, China from 2011 to 2016, to control antimicrobial-resistant bacteria in hospital and provide support to clinicians and decision-making departments.Five dominant bacteria were enrolled based on the data from the general hospital during 6 years. The results of antimicrobial susceptibility testing were interpreted according to Clinical and Laboratory Standards Institute (CLSI). From 2011 to 2016, a total of 19,260 strains of bacteria were isolated, of which Klebsiella pneumoniae, Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa and Acinetobacter baumannii accounted for 51.98%. The resistance rate of K. pneumoniae and E. coli to carbapenem was less than 15%, but resistance of K. pneumoniae to carbapenems increased with time and resistance of E. coli to meropenem increased. The rate of extended-spectrum beta-lactamase (ESBL) production among K. pneumoniae and E. coli was decreasing. For most antibiotics, the resistance rate of ESBL-positive isolates was higher than that of ESBL-negative isolates, excluding carbapenems and cefoxitin. For S. aureus, the rate of methicillin-resistant S. aureus (MRSA) was stable. Resistance of S. aureus to mostly antibiotics decreased with time. Besides polymyxin B, P. aeruginosa and A. baumannii showed high resistance to other antibiotics. For A. baumannii, the resistance rate to mostly antibiotics was increasing. The bacteria showed high levels of resistance and multiple drug resistance. Continuous surveillance and optimizing the use of antibiotics are essential.

Correlation analysis between chief nurse's integrity leadership behavior and nurses' work restriction

Objective To explore the status quo of chief nurse's integrity leadership behavior perceived by nurses and nurses' work restriction and to discuss the correlation between the two. Methods Nurses from 5 internal medicine departments, 5 surgery departments, the emergency department, the intensive care unit, the obstetrics and gynecology department and the operation room from a ClassⅢ Grade A hospital in Zhengzhou were selected by hierarchical sampling, between October and December 2016, and investigated with the Integrity Leadership Questionnaire and the Work Restriction Questionnaire for Nurses. Pearson correlation analysis was used to analyze the relationship between the two. Totally 300 questionnaires were distributed, and 280 questionnaires were collected, with a recovery rate of 93.3%. Results The total scores chief nurse's integrity leadership behavior and work restriction in the 280 nurses were (32.26±4.13) and (40.23±10.06) , respectively. The 4 dimensions of chief nurse's integrity leadership behavior were negatively correlated with the total score of nurse's work restriction (P<0.05) . Conclusions Chief nurse's integrity leadership behavior and nurses' work restriction at a medium level. Nurses' working efficacy may be improved by improving chief nurse's integrity leadership behavior. Key words: Nurses; Chief nurse; Integrity leadership; Work restriction

Correlation between treatment compliance and rumination among maintenance hemodialysis patients

Objective To explore the correlation between treatment compliance and rumination among maintenance hemodialysis (MHD) patients and to analyze the influencing factors of treatment compliance. Methods From June 2016 to June 2017, we selected 180 MHD patients of the Seventh People's Hospital of Zhengzhou by convenience sampling. All of the patients were divided into poor compliance group (n=53) and good compliance group (n=127) according to the judgment criteria for MHD compliance. We collected clinical data of two groups and investigated the rumination of patients between two groups with the Chinese Version of Event Related Rumination Inventory (ERRI) . Spearman rank correlation was used to analyze the correlation between treatment compliance and rumination of patients. Besides, the Logistic regression was used to analyze the influencing factors of treatment compliance among patients. Results There were statistical differences in sexes, ages, educational status, family monthly earning, the ratio of medical reimbursement and time of dialysis between poor compliance group and good compliance group (P<0.05) . The score of intrusive rumination in good compliance group was lower than that in poor compliance group; the score of purposive rumination and total score of rumination in good compliance group were higher than those in in good compliance group, all with significant differences (P<0.05) . Spearman rank correlation analysis showed that treatment compliance was positively correlated with purposive rumination and total score of rumination and negatively correlated with intrusive rumination (P<0.01) . Logistic regression analysis indicated that the influencing factors of treatment compliance of MHD patients included sexes, educational status, family monthly earning, time of dialysis and level of rumination (P<0.01) . Conclusions There is a correlation between treatment compliance and rumination among maintenance hemodialysis MHD patients. Nurses should pertinently improve patients' purposive rumination and reduce intrusive rumination so as to improve patients' treatment compliance, treatment effects and quality of quality. Key words: Dialysis; Patient compliance; Rumination; Correlation

Analysis of AIDS epidemic and clinical features in some part regions of Henan province during 2006-2015

Objective To discuss the epidemiology and clinical characteristics of AIDS in some part of Henan regions. Methods Retrospective analysis was conducted based on the clinical and epidemic information collected from AIDS patients who were treated in the Sixth People's Hospital of Zhengzhou between 2006 and 2015 in He'nan province. Results Between 2006 and 2015, the number of hospitalization increased every year.The average growth rate was 20.31%.The average age of patients was (43.91±13.56) years old.The patients from 40 to 60 years old group occupied 54.06% of total patients, and 71.12% of patients were farmers.During 2006 to 2015, the propagation path changed a lot.Before 2008, blood transmission was the major propagation path (72.72%), but after 2013, the major propagation path was sexual activity (59.69%).40.41% of patients were infected by two or more opportunistic infections.The top five opportunistic infections were bacterial pneumonia (32.68%), tuberculosis (19.29%), fungal infection (18.65%), pneumocystis carinii pneumonia (12.96%), extra pulmonary tuberculosis (7.45%). The death rate was 5.79%.The number of CD4 cells in peripheral blood was closely related to the severity of illness. Conclusion Early anti-virus treatment and opportunistic infection control are key factors to relieve the severity of illness and reduce the death rate. Key words: Acquired immunodeficiency syndrome; AIDS-related opportunistic infection; Epidemiology

Application of modified PG-SGA in the nutritional assessment of patients with chemotherapy after gastric cancer surgery

Objective To apply Scored Patient-Generated Subjective Global Assessment (PG-SGA) , modified PG-SGA, and nutrition risk screening (NRS 2002) in postoperative gastric cancer patients undergoing chemotherapy, and discuss their efficiency of nutritional assessment. Methods A total of 103 gastric cancer patients who received curative resection and underwent chemotherapy in the Gastrointestinal Surgery of a Class Ⅲ Grade A hospital in Zhengzhou from September 2014 to March 2016 were recruited in the study. The general data questionnaire, PG-SGA, modified PG-SGA, and NRS 2002 were applied in the nutritional assessment. The specificity and sensitivity of each screening tool were assessed, and their consistency was analyzed by calculating Kappa value. Results The incidence of malnutrition was up to 73.79% after the postoperative radical treatment of gastric cancer. Area under the curve of the modified PG-SGA during the early stage of chemotherapy, mild chemotherapy, and late chemotherapy were 0.829, 0.853, and 0.924; the Kappa value were 0.683, 0.697, and 0.853, respectively. Conclusions The modified PG-SGA, which is consistent with PG-SGA and has good accuracy, can be used for dynamic nutritional assessment of patients undergoing postoperative chemotherapy. Key words: Nutritional assessment; Antineoplastic combined chemotherapy protocols; Scored Patient-Generated Subjective Global Assessment; Nutrition risk screening

Current status of disaster preparedness in emergency nurses in Class III Grade A hospitals and its influencing factor

Objective To explore the current status of disaster preparedness in emergency nurses in Class Ⅲ Grade A hospitals and its influencing factors, and to offer reference for disaster nursing management and nursing education. Methods Totally 146 emergency nurses from 2 ClassⅢ Grade A hospitals in Zhengzhou from March to April 2017 were selected by purposive sampling and investigated with disaster preparedness evaluation tools. Results The total score in disaster preparedness for emergency nurses was (188.79±35.02) at a medium level. Nurses experienced in disaster relief, aged 26 to 35, with bachelor degrees and working for 5 to 10 years showed higher scores in disaster preparedness than other nurses (t=2.298, 4.917, 4.733, 7.230; P<0.05) . Conclusions The disaster preparedness in emergency nurses needs to be enhanced, and attention should be paid to improving the disaster relief nursing education and training system. Key words: Nurses; Emergency service, hospital; Disaster; Preparedness