Analysis of AIDS epidemic and clinical features in some part regions of Henan province during 2006-2015

Abstract

Objective To discuss the epidemiology and clinical characteristics of AIDS in some part of Henan regions. Methods Retrospective analysis was conducted based on the clinical and epidemic information collected from AIDS patients who were treated in the Sixth People's Hospital of Zhengzhou between 2006 and 2015 in He'nan province. Results Between 2006 and 2015, the number of hospitalization increased every year.The average growth rate was 20.31%.The average age of patients was (43.91±13.56) years old.The patients from 40 to 60 years old group occupied 54.06% of total patients, and 71.12% of patients were farmers.During 2006 to 2015, the propagation path changed a lot.Before 2008, blood transmission was the major propagation path (72.72%), but after 2013, the major propagation path was sexual activity (59.69%).40.41% of patients were infected by two or more opportunistic infections.The top five opportunistic infections were bacterial pneumonia (32.68%), tuberculosis (19.29%), fungal infection (18.65%), pneumocystis carinii pneumonia (12.96%), extra pulmonary tuberculosis (7.45%). The death rate was 5.79%.The number of CD4 cells in peripheral blood was closely related to the severity of illness. Conclusion Early anti-virus treatment and opportunistic infection control are key factors to relieve the severity of illness and reduce the death rate. Key words: Acquired immunodeficiency syndrome; AIDS-related opportunistic infection; Epidemiology