Quantitative detection of myocardial edema in acute myocardial infarction based on T2 mapping

Abstract

Objective To investigate the clinical significance of quantitative detection of myocardial edema in acute myocardial infarction based on T2 mapping. Methods From July 2018 to February 2019, a total of 20 patients (observation group) who underwent cardiac MRI after interventional therapy in the People's Hospital of Wenzhou were enrolled.Another 20 healthy volunteers were selected as the control group.The image data of the observation group were collected, and the image data were post-processed.The T2 value, edema area and microcirculation obstacle area of the infarcted myocardium and its contralateral normal myocardium were measured and recorded by the image information.The infarcted myocardium and the contralateral normal myocardium were recorded.The T2 values were compared and the cardiac MRI, cardiac function, serological markers and heart failure related products of the two groups were compared. Results The patients in the observation group underwent self-comparison between infarcted myocardium and normal myocardium.The T2 value of the distal infarcted myocardium was (90.14±.51)ms, which was greater than that of the normal myocardium [(60.71±5.15)ms], the difference was statistically significant(t=8.49, P<0.05). The number of myocardial microvascular obstruction (MVO) in the observation group was 17 cases, which in the control group was 0 cases, the difference was statistically significant (χ2=41.45, P<0.05). The left ventricular end-diastolic volume of the observation group[(88.5±16.2)mL] was higher than that of the control group[(72.4±15.1)mL], and the difference was statistically significant (t=12.51, P<0.05). The ejection fraction of the observation group was (54.1±11.2)%, which was lower than that of the control group [(71.2±7.9)%], and the difference was statistically significant (t=18.71, P<0.05). The T2 value of the observation group was (69.4±6.4)ms, which was higher than that of the control group[(55.2±11.4)ms](t=11.98, P<0.05). The degree of myocardial delayed imaging (LGE) in the observation group was 13%, which in the control group was 0%, the difference was statistically significant (Z=27.62, P<0.05). T2 mapping showed that myocardial infarction sensitivity and positive predictive value were higher, but its specificity was relatively low. Conclusion Quantitative T2 mapping has high clinical value in the evaluation of myocardial edema after acute myocardial infarction.T2 mapping can be used to analyze the extent of lesions in patients with acute myocardial infarction. Key words: Magnetic resonance imaging; Myocardial infarction; Myocardial ischemia; Edema; Creatine kinase; Stroke volume; Troponin; Cardiac imaging techniques