Abstract

目的 观察胸腺法新联合化疗治疗非小细胞肺癌的临床效果及其对患者免疫功能的影响。 方法 选取新野县人民医院2017年1月至2019年1月收治的非小细胞肺癌患者58例,采用随机数字表法分成两组,每组29例。对照组采用紫杉醇、卡铂方案化疗,观察组采用紫杉醇、卡铂方案化疗联合胸腺法新治疗。观察两组临床疗效及免疫功能(CD4+、CD8+、CD4+/CD8+)的变化。 结果 观察组总有效率为93.1%(27/29),高于对照组的65.5%(19/29),差异有统计学意义(χ2=5.874,P<0.05)。治疗后,观察组CD4+、CD8+、CD4+/CD8+分别为(52.3±1.6)%、(20.5±1.0)%、(2.6±0.5),均高于对照组的(44.6±1.7)%、(17.6±1.1)%、(2.3±0.4),差异均有统计学意义(t=17.813、10.506、4.515,均P<0.05)。 结论 胸腺法新联合紫杉醇、卡铂方案化疗可显著提高非小细胞肺癌患者的治疗效果,改善患者的免疫功能。

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