Understanding and modeling the mechanical behavior of biological systems requires high quality experimental data to be acquired and analyzed. Conventional indentation tests assume homogeneous linear elastic material properties, and therefore are of limited use in characterizing inhomogeneous biological tissues that generally exhibit complex nonlinear elastic response. Despite their shortcomings, the Hertzian models commonly applied in the analysis of the indentation of soft materials are accurate for determining the quasi-static elastic properties of many synthetic gels when applied within their restrictions, including small strain deformation.
Read full abstract