Herbal Cream Research Articles

Formulation and Evaluation of Herbal Antifungal Cream of Zingiber officinale

The aim of the study was to formulate a cream containing a composition to treat fungal infections of the skin and improve skin properties. This preparation belongs to medicinal creams containing antifungal agents. It reveals a formula for treating skin fungal infections. For skin infections, a topical approach is the best option. Developing a local drug delivery system with systemic action may be advantageous for a variety of drugs, as it offers many advantages over traditional drug administration routes. Ginger extract is an active pharmaceutical ingredient (API) used to treat fungal skin infections. The cream base also contains two primary and secondary emulsifiers, a waxy substance, a co-solvent, two preservatives, a buffer, a humectant, and water. When the active ingredients combine, they exert a powerful antifungal effect. Several experiments were performed to evaluate the physico-chemical properties of formulated creams, including: B. Visual inspection, pH measurement, homogeneity, removal test, skin irritation test, viscosity, spreadability test, saponification value, acid value, etc. The antifungal effect of the cream was further analyzed using nutrient agar. The medicated cream had good viscosity and color. However, the scent of ginger was characteristic.

Formulation Of Herbal Cream to Treat Dry Skin

The main aim of the present article is to reduce the adverse effect associated with synthetic dry skin cream by formulating an herbal dry skin cream for treatment of dry skin. Abnormally dry skin Can be occurring due to a dry weather, winter weather, acute deficiency of vitamin A, systemic illness, over exposure to sunlight, or medication. The skin loses moisture. It may crack and peel. Or it may become irritated, inflamed, and itch. Bathing repeatedly, especially with soaps, can contribute to dry skin. This research mainly based on the treatment of dry skin by using various herbs and making poly herbal formulation. Herbs such as cucumis sativus (main fruit juice) used as repair dry skin and damaged skin, moisturizer, azadirachta indica (neem leaves) used as skin moisturizer, rose water(rose water) used as cooling agent, flavouring agent, emollient, tulasi (tulasi leaves) used as antioxidant and skin texture improve, antimicrobial agent, amla (amla fruit) used as antioxidant and vitamin C help to brighten your skin, vitamin E used as moisturizer skin, lotus flower(lotus petals) used as anti-inflammatory and which help balance sebum production, improve the texture and elasticity of the skin, cool. Natural herbal extract in combination effectively utilized for the treatment of dry skin. Use of such product far better than the use of synthetic cream for the control of dry skin.

Developing Science Skills and Introducing Traditional Herbal Medicine to Children through Science Experiment: Making Ice Cream

This activity aims to explain how the science experiment of making herbal ice cream can be used as an engaging and enjoyable method to teach science and culture. The activity took place at SD Negeri 1 Kismoyoso, Ngemplak District, Boyolali, Central Java. It was designed to help students gain understanding of scientific concepts such as chemical reactions and changes in the state of matter, as well as introduce them to the diversity of local medicinal plants. The students at SD Negeri 1 Kismoyoso were engaged in the practical process of making ice cream using herbal ingredients, specifically ginger. They also learned about the health benefits of each herbal ingredient used in making the ice cream and its connection to the scientific concepts underlying the ice cream-making process. The results of this activity demonstrated that the science experiment of making herbal ice cream can help students develop scientific skills such as observation and experimentation. Students were able to learn about various medicinal plants and their properties, as well as how these plants can be utilized to create healthy and delicious ice cream. The science experiment of making herbal ice cream serves as an effective learning method to help students explore science and culture in a holistic manner.

The efficacy of Chinese herbal ointment in treating perianal eczema: A systematic review and meta-analysis.

Traditional Chinese herbal ointment has significant curative effect and few side effects in the treatment of perianal eczema (PE). Currently, there is no systematic evaluation on the treatment of PE with traditional Chinese medicine ointment. The current aim is to systematically evaluate the efficacy of traditional Chinese medicine ointment in the treatment of PE through meta-analysis. Randomized controlled trials on the treatment of PE with Chinese herbal plaster were included in the meta-analysis, which was searched in Chinese and English databases up to March 1, 2023. The search will be conducted in accordance with the object of PICOS framework. Two research will independently use EndnoteX9 to extract the data and evaluate the quality assessment of included trails. Meta-analysis was performed using Revman5.4.1 provided by Cochrane Collaboration; when the outcome indicator is a dichotomous variable, relative risk (RR) was used as the effect size; when the outcome indicator is a continuous variable, weighted mean difference (MD) was used as the effect size, each effect size should be expressed as 95% confidence interval (CI). The results of meta-analysis showed that: The total effective rate of PE (RR: 1.22, 95% CI: 1.15, 1.30, P < .01; I2 = 32%, Q = 0.17). The cure rate of PE (RR: 3.37, 95% CI: 2.30, 4.94, P < .01; I2 = 21% Q = 0.26). The recurrence rate of PE (RR: 0.25, 95% CI: 0.13, 0.48, P < .01; I2 = 31%Q = 0.23). Itchy points (MD: 0.04, 95% CI: -0.19, 0.27; I2 = 26%) Skin damage area (MD: -0.37, 95% CI: -0.56, -0.19; I2 = 26%). Skin damage form (MD: -0.59, 95% CI: -0.81. -0.36; I2 = 0%). A total of 11 articles were included in this study for meta-analysis, and the results showed that Chinese medicine ointment is more helpful in improving the skin lesion area and skin damage form, significantly improve the response rate and cure rate, reduce the recurrence rate. Chinese herbal ointment has guiding significance for clinical practice which deserve to use ointments by further experimental and clinical investigation.

Antibacterial and Cytotoxic Effects of Urtica dioica Hydro-alcoholic Extract on Causative Bacteria of Mastitis and Epithelial Cells of Bovine Mammary Gland in vitro

Background &amp; Objectives: Nowadays, owing to positive features of herbal plants, they are widely being applied to treat different diseases. The current study was designed to assess antibacterial activities and cytotoxic effects of hydro-alcoholic extract of Urtica dioica (U. dioica) on causative bacteria of mastitis and epithelial cells of bovine mammary gland in vitro.&#x0D; Materials &amp; Methods: Hydro-alcoholic extract of U. dioica was provided, then minimum inhibitory concentration (MIC) 50 and MIC90 of the extract (µg/mL) was determined against both Escherichia coli and Staphylococcus aureus. Finally, after isolation and culture of epithelial cells of bovine mammary gland, cytotoxic effects of MIC50 and MIC90 concentrations of the hydro-alcoholic extract were evaluated using MTT assay during 24 and 48 h.&#x0D; Results: The hydro-alcoholic extract could inhibit growth of both E. coli and S. aureus, with higher inhibitory effect on S. aureus than that of E. coli. For both species, MIC50 concentration was 312.5µg/mL concentration of hydro-alcoholic extract and MIC90 was 39.06 µg/mL. The results of MTT assay confirmed that viability of the epithelial cells for MIC50 concentration during 24 and 48 h was 68% and 28%, respectively. Additionally, cell viability for MIC90 concentration in 24 and 48 h was 50% and 6 %, respectively.&#x0D; Conclusion: According to our results, it can be concluded that despite bactericidal activity of U. dioica extract, cytotoxic effects was observed at antibacterial levels. Hence, further formulations are required to treat mastitis using this herbal ointment.

Comparative efficacy of Jaungo, a traditional herbal ointment, and a water-in-oil type non-steroidal moisturizer for radiation-induced dermatitis in patients with breast cancer: a prospective, randomized, single-blind, pilot study.

Background: Radiation-induced dermatitis (RID) is one of the most prevalent side-effects of conventional cancer therapies; however, there is no standard treatment for its prevention. Therefore, this study aimed to evaluate the comparative efficacy and safety of Jaungo (mainly composed of Lithospermum erythrorhizon Siebold & Zucc. and Angelica sinensis (Oliv.) Diel) and the water-in-oil-type non-steroidal moisturizer for the prevention of RID in patients with breast cancer (BC). Methods: This is a prospective, single-blind, pilot randomized controlled trial. Between March 2021 and July 2022, 50 patients were randomly selected to use Jaungo or the moisturizer while undergoing postoperative radiation therapy (RT). Assessments were conducted nine times-every week while the patients underwent RT and 2weeks after the end of therapy. The primary outcome was the incidence rate of RID grade ≥2. The secondary outcomes were the incidence rate of maximum grade RID, time to RID onset, RID-related quality of life (QOL) score, pain intensity, and adverse events. Results: The incidence rate of RID grade ≥2 was 24.0% and 20.0% in the Jaungo and the moisturizer groups, respectively, with no significant difference between the groups (p = 0.733). Regarding the secondary outcomes, the incidence rate of maximum grade RID (p = 0.890), mean time to RID onset (p = 0.092), cumulative incidence rate of RID (p = 0.280), RID-related QOL score, and maximum pain intensity (p = 0.844) also did not differ significantly between the groups. None of the subjects in either group experienced severe adverse effects, although one participant in the moisturizer group had mild fever and insomnia. Conclusion: These findings suggest that Jaungo has preventive efficacy without severe side-effects against RID in patients with BC that is comparable to that of the water-in-oil type non-steroidal moisturizer. Further extensive randomized controlled trials with larger sample sizes are warranted to validate our findings. Clinical Trial Registration: Clinical Research Information Service (CRIS), https://cris.nih.go.kr, identifier KCT0005971.

A REVIEW ON CHARACTERIZATION OF ANTI-AGING HERBAL VANISHING CREAM

The objective of the current study endeavour was to develop and evaluate a vanishing herbal cream. Herbal creams offer a number of advantages over other creams. The majority of creams on the market today that are based on synthetic drugs like acyclovir, triamcinolone, calcipotriene, and mometasone make the skin fairer, but they also have a lot of unfavourable side effects like itching or many allergic reactions. Herbal creams provide the skin a fairer appearance because they don't have any of these side effects. The method for making the herbal cream was really simple. At 700C, a combination of stearic acid (17%), potassium hydroxide (0.5%), and sodium carbonate (0.5%) was melted to generate the oil phase. A crude medicine extract made from kachora plant rhizomes, nagarmotha fruit, pimpali fruit, nutmeg fruit, jawas seed, turmeric rhizome, wheat grains, urad and harbhara cereals (all 4.5%), glycerin (6%), and water (71%) that has been heated to 700C was used in the second phase. The aqueous phase was then added at 700C while the oil phase was continually agitated after that. It was stirred and brought to room temperature after the transfer was complete. The perfume was added last, just before the finished product was moved to the proper container. The aforementioned herbal cream underwent testing. Physical traits like pH, visual and tactile homogeneity, colour, rubout (spreading ability, wetness), smear kind, and emollient were noted. More research is needed to examine how well this composition performs.

Formulation and Evaluation of Herbal Excipients-Based Ketoconazole Cream for Fungal Infection

The goals of the current studies were to create herbal excipients-based ketoconazole cream to enhance the efficacy against chronic mucocutaneous candidiasis. Ketoconazole, coconut oil and other herbal excipients namely shea butter, bees wax, Lanolin and Rose oil were used for the formulation. Each formulation was prepared with various concentrations of coconut oil. Every prepared formulations were evaluated successfully. Among all the formulations F4 was the best that exhibiting a higher in vitro diffusion rate 59.6 ± 0.10 % CDR within 480 min with maximum antifungal efficacy, compared with the marketed formulation. We might therefore say that herbal excipients-based cream improved patient compliance and is a superior alternative to oral preparation, easier administration, local bioavailability, and better results for individuals with persistent mucocutaneous candidiasis who are afflicted with fungi.

Antiacne Herbal Cream

Abstract: Objective- To formulate and evaluate herbal cream using Aloe Vera gel, Sandalwood Powder , extracts of Neem (Azadirachta indica) and Tulsi (Ocimumtenuiflorum) to give antiacne effect. Method: A cream with an oil-in-water (O/W) emulsion base (semisolid formulation) was created. The oil phase (Part A) was heated to 75° C while the emulsifier (bees wax) and other oil soluble components (liquid paraffin, rose oil) were dissolved in it. The water soluble additives and preservatives components (aloe vera ethanol extract, vitamin C, borax, methyl paraben, sandalwood, and Neem and Tulsi were dissolved and heated to 75° C in the aqueous phase (Part B). Once heated,parts of the aqueous phase were introduced to the oil phase while stirring continuously till cooling of Emulsifier was used. Results: The formulation showed good appearance, pH, viscosity, phase separation. Conclusion: All four herbal components demonstrated noticeably distinct behaviours. Based on the findings, we may infer that all of the formulations were stable and safe to apply to the skin, with acceptable viscosity and no evidence of phase separation. Additionally, the formulation had no redness, Itching and erythrema .When conducting the irritancy testing, they were simple to clean. The formula read at room temperature, stable

The Effect of a Combined Topical Herbal Cream on the Incidence and Severity of Striae Gravidarum in Primiparous Women: A Randomized Clinical Trial

Background: Striae gravidarum, which occurs in most pregnancies, is unpleasant for women, and its treatment is costly. A preventive measure for this condition is applying herbal oils to maintain the skin's elasticity. The current study investigated the effect of a topical combined herbal cream on the occurrence and severity of striae gravidarum in primiparous women. Methods: In this triple-blind randomized clinical trial, 90 primiparous women in their first trimester of pregnancy, attending healthcare centres in Mashhad, Iran, were randomly allocated into two groups of herbal cream and placebo, from which 54 completed the study. The intervention group received 0.3 g of the cream, topically, composed of Calendula (Pot marigold), Anthemis nobilis (Chamomile), Pelargonium Graveolens (Rose Geranium), Theobroma oil (Cocoa Butter) and Soybean, twice a day for three days a week from 14-16 to 27-30 weeks of gestation and the placebo group received a moisturizing cream. At the gestational age of 38-40 weeks, the incidence and severity of striae on the abdominal skin were evaluated using the Atwal numerical scoring system and digital photography. Results: There was a significant difference between the prevalence of striae in the intervention and placebo group (43.3% vs 87.5%) (P&lt;0.0001). Also, a significant difference was seen between the two groups in terms of the severity of the striae (P &lt; 0.001). In the intervention group, the severity of striae in 86.7%, 13.3%, and 0% of the cases was mild, moderate, and severe, respectively, whereas, in the placebo group, it was occurred as mild, moderate, and severe in 37.5%, 58.3%, and 4.2% of the cases. Conclusion: Considering the effect of topically applied herbal cream, it is recommended that health care providers suggest pregnant women to use such herbal creams to avoid striae gravidarum development. Clinical Trial Registration Number: IRCT20190305042927

Evaluation of Wound Healing Potential of Root Bark Extract of Berberis aristata and Molecular Docking Analysis of Berberis Phytoconstituents.

The root bark of Berberis aristata has been utilized by indigenous peoples for wound treatment for centuries. The mature root barks are crushed into a paste and applied to the wound's surface. The focus of this research is to analyse the wound healing activities of an ethanolic extract of Berberis aristata, as well as to use molecular docking to establish the likely mechanism of the potent phytochemical. There is no scientific evidence to support the usage of root bark extract of Berberis aristata. The Herbal ointment, which comprises (1%, 2%, and 4% w/w) ethanolic extract of root bark, was developed to test the wound healing ability of incision and excision wounds, and the molecular mechanism was established using Auto-Dock software. Epithelization stage, wound index, % wound contraction area, hydroxyproline content, DNA estimate, and histopathological assessments were performed on the incision wound model. Tensile strength was assessed in an excision wound model. TLC was used to identify the samples after successive extractions with different solvents based on polarity. Berberine and tetrahydropalmatine were major active phytoconstituent found in root barks of Berberis aristata as secondary metabolites. Animals treated with 4% w/w formulation demonstrated considerable wound contraction, epithelization time, and wound index in the excision model. In contrast, to control and standardize the concentrations of hydroxyproline, total amino acids, and DNA in recovering tissue were higher. At 4% w/w extract formulation, the parameters studied indicated a substantial result. Berberine and tetrahydropalmatine, active metabolites which are present in the ethanolic extract of Berberis aristata, were found to be responsible for wound healing. Based on ligand interactions, the findings verified Berberis aristata ethnomedicinal claim in a wound healing capacity.

Formulation Development And In Vitro- Assesment Of Herbal Anti-Bacterial Cream

Objectives of the study: To evaluate various formulation factors and the topical cream formulation of Cassia Siamea flower extract for antibacterial activity. Phytochemical screening and characterization of the topical formulation (cream) made from the alcoholic extract are done after the extraction of Cassia Siamea.&#x0D; Materials and Methods:A suitable procedure was used to gather and extract the plants. The yield of the extract was estimated after drying. The broth dilution method was used to determine the MIC. This made it easier to determine the formulation's yield quantity. This yield was used to create cream, after which evaluations were conducted to test the product's quality.&#x0D; Results and Discussions: Began with the extraction and was followed by confirmation of the phytochemical evaluation. According to the confirmatory study, the ethanolic extract was devoid of saponins and glycosides. Tannins, phenolics, flavonoids, and alkaloids were also discovered, but not these carbohydrates. In MIC testing, the Cassia Siamea flower extract shown good activity and effectively inhibited the growth of Propionibacterium acnes and Pseudomonas aeruginosa. The designed composition produced a very smooth cream. In accordance with I. P., evaluations were also discovered to be within the range of conventional formulas. Evaluations revealed that the overall formulation had good activity against microorganisms.&#x0D; Conclusion: This study reveals that a range of phytochemicals are present in Cassia siamea flowers as an active component, producing positive findings against antibacterial activity and showing great promise as an antibacterial agent. This study also comes to the conclusion that the extraction of Cassia Siamea flowers is essential for the development of better, safer, and more affordable drugs to treat different bacterial illnesses.&#x0D;

Formulation, Characterization and In Vitro Evaluation of ProShine MBTMGMIHS Herbal Sunscreen cream containing Flower Extract

The primary goal of this research was to develop and test a herbal sunscreen cream containing Hibiscus (Hibiscus rosasinensis) and Rose flower extracts (Rosaceae). Hibiscus and Rose extractswere used in the formulation of oil in water (O/W) emulsion-based cream. Flower extracts were preparedusing the Soxhlet apparatus. The physicochemical parameters of the formulated herbal sunscreen creams were tested, including colour, odour, spreadability, pH, and viscosity.The centrifugation process was used to conduct the stability and sensitivity tests. A UV Spectrophotometric method of Mansur et al. was used to calculate the in-vitro SPF of the formulations. The flower extract-based sunscreen cream provided high absorbance in the 290-320nm wavelength range, with an SPF of 38.12-42.24. The ProShine MBTMGMIHS herbal formulation was found to be stable, spreadable, homogeneous, non-greasy, and displayed no signs of phase separation. The pH of the cream was found to between 5.5-6 which is nearer to the skin's pH.Also, after the microbial evaluation of ProShine MBTMGMIHS herbal sunscreen, no bacterial or fungal contamination was observed after incubation for a long period.We may assume from the study's findings that the formulated sunscreen can greatly improve and add to the UV absorption properties of conventional sunscreen formulations. It would also aid in the broadening of the sunscreen's UV defence performance, with the added benefit of preventing the negative and undesirable effects of synthetic sunscreen compounds.

Formulation and evaluation of herbal cream using ethanolic extract of Emblica officinalis for antibacterial activity

Skin infections occur commonly and after present therapeutic challenges to practioners due to the growing concerns regarding multidrug resistant bacterial, viral and fungal strain. The aim of present study was to formulate topical cream using Ethanolic leaves extract Emblica officinalis and evaluate In­­- vitro study the antibacterial activity of the ethanolic extracts of dried leaves of Emblica officinalis was determined by using the Agar cup plate method versus different bacteria such as Staphylococcus aureus, Bacillus subtilis, Escherichia coli and Pseudomonas aeruginosa etc. By blending the ethanolic extract of Emblica officinalis (10 % w/w) into aqueous cream we formulated herbal cream. Formulation of herbal cream evaluation their physio-chemical properties, in vitro drug release and in vitro Antibacterial Activity against Staphylococcus aureus, Bacillus cereus, Escherichia coli, Pseudomonas aeruginosa. The herbal cream formulation A5 show better release and effective against bacterial strain

Analgesic Effectiveness of Physical Therapy Combining the Use of Electromagnetic Fields with Light Radiation Emitted by LEDs along with the Use of Topical Herbal Ointment in Patients with Gonarthrosis

(1) Background: The aim of the study is to evaluate the analgesic effectiveness of a physical therapy regimen that combines the use of an electromagnetic field with light radiation emitted by LEDs, along with the use of Traumeel S ointment, in patients with gonarthrosis. (2) Methods: The study included 90 patients with knee osteoarthritis (grade 2 Kellgren and Lawrence osteoarthritis). They were divided into three groups: Group I, 30 patients treated with magnetic stimulation plus LED therapy; Group II, 30 patients treated with Traumeel S ointment; and Group III, 30 patients treated with magnetic stimulation plus LED therapy with Traumeel S ointment. Pain intensity was assessed using the VAS and Laitinen scales before and after a series of treatments. (3) Results: Significant results in terms of pain reduction before and after treatment were obtained in each of the study groups, as there were significant differences in the VAS pain intensity scores before and after the procedures between the groups. In group I, with electromagnetic field and LED light treatment, the difference was 35.5; in group II, which received Traumeel S® ointment, the difference was 18.5; and in group III, with electromagnetic field and LED light treatment as well as Traumeel S ointment, the difference was 26.5. In the Laitinen scale, the differences were insignificant, although the size distribution was similar. (4) Conclusions: The therapy used in this study showed that magnetic stimulation plus LED therapy and the use of Traumeel S ointment gave positive results in terms of pain reduction in each of the study groups. The strongest analgesic factor seems to be magnetic and LED therapies used separately. Traumeel S in magnetoledophoresis does not work synergistically with the magnetic field of LED light, and even worsens the effect of the therapy used.

Efficacy and Safety of Cream Containing Dipotassium Glycyrrhizinate, Vaccinium myrtillius, Epigallocatechin Gallatyl Glucoside, and Tamarindus indica Compared with Triamcinolone Acetonide Cream in Eczema and Psoriasis

Background: Topical corticosteroids are the main treatment in eczema and psoriasis. However, long-term use of corticosteroids causes unwanted adverse effects. Dipotassium glycyrrhizinate (DPG) HERB cream, containing DPG, Vaccinium myrtillius, epigallocatechin gallatyl glucoside, and Tamarindus indica, has an anti-inflammatory and antioxidant effect by inhibiting histamine release and proinflammatory cytokine production so a natural herbal cream is required for alternative treatment. Objective: To evaluate the efficacy and safety of DPG-HERB. Materials and Methods: The present study was a right-left, double-blinded, randomized clinical trial in participants with eczema or plaque psoriasis on both sides of the body. DPG-HERB was applied to the lesion on one side of the body, while 0.1% triamcinolone acetonide (TA) cream was applied to the lesion on the other side, twice daily for four weeks. Disease severity as eczema area and severity index (EASI) in eczema, and psoriasis area and severity index (PASI) in psoriasis, skin biophysics as corneometry and transepidermal water loss (TEWL), and clinical assessments as erythema, scale or excoriation, and lichenification or thickness, were evaluated at baseline, week 2 and week 4 after treatment. The dermatology life quality index (DLQI) was performed at baseline and week 4. Adverse effects were recorded during each visit. Results: The evaluation of the 75 patients with 150 lesions in the present study, DPG-HERB and TA cream showed significant improvement in all the evaluated characteristics of eczema (p&lt;0.05), however, in psoriasis, both creams showed significant improvement in skin biophysics, PASI, scale, and thickness (p&lt;0.05), but DPG-HERB was less effective in decreasing erythema (DPG-HERB, p=0.31 and TA, p&lt;0.05) and less improving TEWL compared with 0.1% TA cream (DPG-HERB, p=0.051 and TA, p&lt;0.05). No side effects in the short-term period were reported in either group. Conclusion: DPG-HERB is safe and efficacious in eczema, but less effective in psoriasis comparing to TA cream. Keywords: Eczema; Plaque psoriasis; Dipotassium glycyrrhizinate acid

Kampo herbal ointments for skin wound healing.

The management of skin wound healing problems is a public health issue in which traditional herbal medicines could play a determining role. Kampo medicine, with three traditionally used ointments, provides interesting solutions for these dermatological issues. These ointments named Shiunkō, Chuōkō, and Shinsen taitsukō all have in common a lipophilic base of sesame oil and beeswax from which herbal crude drugs are extracted according to several possible manufacturing protocols. This review article brings together existing data on metabolites involved in the complex wound healing process. Among them are representatives of the botanical genera Angelica, Lithospermum, Curcuma, Phellodendron, Paeonia, Rheum, Rehmannia, Scrophularia, or Cinnamomum. Kampo provides numerous metabolites of interest, whose content in crude drugs is very sensitive to different biotic and abiotic factors and to the different extraction protocols used for these ointments. If Kampo medicine is known for its singular standardization, ointments are not well known, and research on these lipophilic formulas has not been developed due to the analytical difficulties encountered in biological and metabolomic analysis. Further research considering the complexities of these unique herbal ointments could contribute to a rationalization of Kampo's therapeutic uses for wound healing.

In vitro evaluation of the herbal cream formulation from methanolic leaf extracts of Tephrosia vogelii Hook.f for topical application

BackgroundTopical infectious are among of global challenges which propelled up with antimicrobial resistances. This scenario compels for drug discovery and development. Herbal formulation is one of important struggle in the drug development with the purpose of overcoming various diseases distressing health care settings. Thus, this study aimed to formulate and evaluate herbal cream from leaf methanolic extracts of Tephrosia vogelii Hook.f for topical therapies.MethodsHerbal cream was prepared by homogeneously mixing up cream base and methanolic leaf extracts of Tephrosia vogelii. Physicochemical properties and in vitro antimicrobial activities of the cream were evaluated. The stability, colour change, washability and texture were parameters used evaluate physicochemical properties of cream. Disc diffusion method was employed to evaluate antimicrobial activities of the cream against Candida albicans (ATCC 90,028), Escherichia coli (ATCC29953) and Staphylococcus aureus (ATCC25923).ResultsFormulated herbal creams; CBTV1, CBTV2 and CBTV3 with methanolic extracts concentrations content of Tephrosia vogelii 0.05%, 0.10% and 0.25%, respectively, were prepared. All cream formulations were stable, washable by water, green in colour and soft. The CBTV3 product exhibited with high prominent antimicrobial activity compared to the rest, henceforth promisingly to be effective for topical skin therapy.ConclusionThe herbal cream formulation of methanolic leaf extract of Tephrosia vogelii at 0.25% appeared to have more antimicrobial performance. Therefore, it is considered as minimal concentration for the herbal cream formulation in future for clinical trials as a potential antifungal and antibacterial agent product for treatment of skin infections.Graphical

Formation and Evaluation of Herbal Ointment by using Curcuma Longa (Turmeric)

Herbal cosmetics products are natural beauty products that provides the useful benefits to the skin and minimum side effects. It enhances the skins natural beauty whatever the type of the skin. Ointments products in which the herbs are extracted into vegetable oils by various methods It is used in diseases of skin such as whelks, bruises, burns, sprains, pimple, boils water burns, sunburns, piles and catarrh. Whenever you applied ointment to the skin it provides coolness to the skin and healing properties. It nourishes the skin.

Evaluation of Physicochemical and Sensory Properties of Ice Cream Incorporating Processed Amla

Amla incorporated ice cream can be considered as an herbal ice cream and a healthy food and the present study was designed develop various types of Amla ice cream using Amla juice, Amla powder, and dried Amla (candy), and to evaluate its physicochemical and sensory properties during four weeks of storage at 10℃ frozen temperature. The results of this study revealed that, the total solid (37.78±0.02%), fat (8.87±0.31%) and total soluble solid (28.93±0.14%) content were significantly (p&lt;0.05) higher in without Amla incorporated ice cream. The titratable acidity (0.55±0.01%) content was significantly (p&lt;0.05) higher in Amla juice incorporated ice cream. pH was significantly higher without Amla incorporated ice cream (6.58±0.01%). Amla juice incorporated ice cream showed the highest antioxidant activity (131.0mg/ml) and least value (72.14 mg/ml) showed in without Amla incorporated ice cream. The first dripping time was significantly (p&lt;0.05) higher in candy incorporated ice cream (14.29±0.25 min) and lowest value showed in without Amla incorporated ice cream (6.04±0.61 min). During storage, the total solid, ash, fat, total soluble solid content, acidity, and dripping time were significantly (p&lt;0.05) increased. Moisture content, pH content, antioxidant activity and melting rate were significantly (p&lt;0.05) decreased with the storage period. Sensory properties were evaluated though the panel of 10 members. As a result of organoleptic characteristics revealed that, 5% of dried Amla (candy) incorporated ice cream had the highest mean score (throughout the storage period) of overall quality of all sensorial properties namely, color, taste, texture, aroma, and overall acceptability. Finally, it could be concluded that the processed Amla is enriching the ice cream manufacture and it is important to improvement of human nutrition.