Abstract

Abstract: Objective- To formulate and evaluate herbal cream using Aloe Vera gel, Sandalwood Powder , extracts of Neem (Azadirachta indica) and Tulsi (Ocimumtenuiflorum) to give antiacne effect. Method: A cream with an oil-in-water (O/W) emulsion base (semisolid formulation) was created. The oil phase (Part A) was heated to 75° C while the emulsifier (bees wax) and other oil soluble components (liquid paraffin, rose oil) were dissolved in it. The water soluble additives and preservatives components (aloe vera ethanol extract, vitamin C, borax, methyl paraben, sandalwood, and Neem and Tulsi were dissolved and heated to 75° C in the aqueous phase (Part B). Once heated,parts of the aqueous phase were introduced to the oil phase while stirring continuously till cooling of Emulsifier was used. Results: The formulation showed good appearance, pH, viscosity, phase separation. Conclusion: All four herbal components demonstrated noticeably distinct behaviours. Based on the findings, we may infer that all of the formulations were stable and safe to apply to the skin, with acceptable viscosity and no evidence of phase separation. Additionally, the formulation had no redness, Itching and erythrema .When conducting the irritancy testing, they were simple to clean. The formula read at room temperature, stable

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