Abstract
Objective: To formulate and evaluate herbal cream using Aloe Vera gel, dimethyl sulphoxide extracts of Neem (Azadirachta indica) and Tulsi (Ocimumtenuiflorum) to give multipurpose effect.
 Methods: The cream was prepared by using the cream base that is bee’s wax, liquid paraffin, borax, methylparaben, distilled water, rose oil, Aloe Vera gel, dimethyl sulphoxide extracts of Neem and Tulsi. The cream was prepared by using the slab technique/extemporaneous method for geometric and homogenous mixing of all the excipients and the herbal extracts. By using slab technique, we have developed three batches of our herbal cream, namely F1H, F2H, and F3H. All three batches were evaluated for different parameters like appearance, PH, viscosity, phase separation.
 Results: All the three formulations F1H, F2H, F3H showed good appearance, PH, adequate viscosity and no phase separation was observed. Also, the formulations F1H, F2H, F3H showed no redness, erythema and irritation during irritancy study and they were easily washable. All the three formulations F1H, F2H, F3H were stable at room temperature.
 Conclusion: All three herbal ingredients showed significant different activities. Based on the results, we can suggest that all the three formulations F1H, F2H, F3H were stable and can be safely used on the skin.
Highlights
Cream is defined as semisolid emulsions which are oil in water (o/w) or water in oil (w/o) type and these semisolid emulsions are intended for external application [1]
The main aim of our work is to develop a herbal cream which can give multipurpose effect, like moisturizer, reduce acne and skin irritation, reduce skin diseases like eczema, psoriasis, dry skin, wrinkles, rashes etc. and adding glow to the face
Aloe Vera gel is used as a moisturizer, to reduce pimples and acne and used for treatment of burn wounds [2, 3]
Summary
Cream is defined as semisolid emulsions which are oil in water (o/w) or water in oil (w/o) type and these semisolid emulsions are intended for external application [1]. Cream is classified as oil in water and water in oil emulsion. It is applied on outer part or superficial part of the skin and its main ability is to remain for a longer period of time at the site of application. The main aim of our work is to develop a herbal cream which can give multipurpose effect, like moisturizer, reduce acne and skin irritation, reduce skin diseases like eczema, psoriasis, dry skin, wrinkles, rashes etc. We have used three herbal ingredients in our preparation which are Aloe Vera gel, Neem, Tulsi. Aloe Vera gel is used as a moisturizer, to reduce pimples and acne and used for treatment of burn wounds [2, 3]. Tulsi is used to add glow to the skin and to promote wound healing [5]
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