Upper respiratory tract infections (URTIs) commonly befalls both children and adults and is a major cause of mild morbidity. URTIs ranges from mild self-limiting diseases such as common cold to serious life-threatening illnesses such as epiglottitis. The present study was aimed to evaluate the antibacterial activities of Tectona grandis (teak) leaves extractson some pathogenic microorganisms isolated from clinical samples causingURTIs. The antibacterial activities were assayed using the agar well diffusion method. Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) were evaluated using standard microbiological techniques. Phytochemical andmineral compositions of all the extracts were determined. Appreciable quantities of phytochemical such as saponins, tannins, flavonoids, glycosides, anthraquinone and alkaloids were present in both extracts of the plants with flavonoids having a higher percentage. Minerals such as K, Ca, Fe, Na and Fe were presented in both solvents. Heavy metals like Pb, Cd and as were presented in significant quantities in both extracts, however, high amount of the heavy metal composition was observed in the ethanol extract. The plant extracts exhibited varying degrees of concentration-based antibacterial activities against bacteria implicated from URTIs. They showed a high significant antibacterial activity against Escherichia coli, Staphylococcus aureus and Klebsiella pneumoniae. Conclusively, the plant extracts contained several bioactive compounds (phytochemical), thereby validating the use of this plants for therapeutic tenacities. Also, the antibacterial activity of the leaf extracts against the test organisms also supports its usage in traditional medicine practice.
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