Automotive air-conditioning heat pump systems are particular interest worldwide in energy conservation and emission reduction for electric vehicles, hybrid electric vehicles, and fuel cell electric vehicles. Refrigerant charge amount is a key factor for the air-conditioning heat pump system optimization affecting the condensing pressure and subcooling in both heating and cooling modes. In this paper, the influence of the refrigerant charge on system performances was investigated using the experiment method on a secondary loop air-conditioning heat pump system. The typical heat transfer and flow parameters were recorded, and both cooling and heating performances of the system were investigated and illustrated by pressure-enthalpy diagrams. The critical refrigerant charges were determined in both heating and cooling modes. Three typical void fraction correlation models were also applied for the refrigerant charge determination modeling as a system off-design method. Results show that the Hughmark void fraction correlation method has the best prediction of the critical refrigerant charge in both cooling and heating modes.