Silene conoidea L. is a weed commonly grown in subtropical and temperate zone of western Eurasia, and some part of Himalaya. S. conoidea is a small herb height from 20 to 40cm mostly grow as weed in different crops like wheat, barley, mustard, roquette and lentil pea. This is the first attempt to gather utmost information about the species distribution, taxonomy, ethno-medicines, phytochemical analysis, biological activity etc. of Silene conoidea. The present review aim was to collect fragmented information about the species in addition to explore its therapeutic importance in future research opportunities. A total of 100 research articles were reviewed using different sources like; Scopus, web of science, Science direct, google scholar and PubMed. The species are used as multipurpose in different biological activities against microbes, bacteria and as insecticidal. Silene is also important due to high contents of various chemicals compounds. Chemical extracts contain flavones, glycosides, saponins, sterols and glycosides. A research study shows that S. conoidea can be used as an indicator species of gold. Traditional therapeutic values of the species for treating respiratory, antioxidant, anti-diabetic and anticancer are needed to be validated through more research. Ethno-pharmacological and clinical trial research can be subjected for future studies.