This paper provides a comprehensive review on the status of renewable energy developments and hydrogen economy in the Middle East and North Africa region. This region is heavily reliant on fossil fuels for its domestic energy supply and is also considered a global energy exporter. In this regard, an overview of the current state of energy sector in the region is provided. Moreover, the region possesses great potential for renewable energy exploitation due to its climatic advantages. Therefore, the current status of renewable energy utilization within the region's various countries is reviewed by presenting several operational renewable energy-based plants and future projects for deployment of renewable power in the region. Green hydrogen is an important sustainable clean fuel, and its utilization is essential for both environmental preservation and energy security. Thus, the status of hydrogen production and utilization in the region is discussed considering the various operational systems and future hydrogen generation projects. The concept of source, system and service is also incorporated which considers the utilization of clean energy sources for sustainable hydrogen production through environmentally benign pathways. The potential deployment opportunities for the renewable hydrogen production are also discussed based on available renewable sources in the region. Moreover, this paper discusses the challenges of increasing renewable energy utilization in the region. Furthermore, this paper provides a road map for achieving renewable hydrogen economy including a reduction in domestic utilization of oil and gas sources, subsidization of renewable production sector, and financial support to hydrogen production and transportation infrastructure.