Functional Mesoporous Materials Research Articles

One-step grafting of phenyl functionalized magnetic mesoporous nanocomposites for magnetic dispersive solid-phase extraction and determination of triazole fungicide residues in strawberry fruits

In this work, phenyl-SBA-15@Fe3O4 organic phenyl functional magnetic mesoporous materials were synthesized as adsorbent for magnetic dispersive solid phase extraction (M−DSPE) sample pretreatment. Seven triazole fungicides were simultaneously analyzed by high-performance liquid chromatography coupled with ultraviolet detection (HPLC-UV). The extraction recovery was 82.7 %-88.6 %, and the concentration factor was 10.6–30.8. Under the optimized experimental conditions, the regression equations of seven triazole fungicides showed a good linear relationship, the coefficient of determination r2 was 0.9993–0.9999, and the detection limit was 0.19 ∼ 1.75 μg·L-1. Six strawberry samples were randomly purchased from different places in the market, and flesh,cortex, sepal, and pulp were detected separately. The results showed that flutriafol, triadimenol and difenoconazole were detected, of which flutriafol was detected from all of them and most of them exceeded the national standard. The extraction pretreatment technology is fast and efficient, which can meet the requirements of simultaneous analysis of triazole fungicide residues in strawberries.

Fluorescent and ratiometric probe for tetracycline antibiotics based on metal-chelated functional mesoporous silica

The need to create efficient detection techniques for tetracycline antibiotics (TCs) is pressing, as their overabundance can be damaging to ecosystems and human health. In this work, phenylterpyridine and aminopropyl functionalized mesoporous silica (APT–SBA–15) was chelated with Zn2+, and the metal-chelated functional mesoporous silica material (APT–SBA–15@Zn2+) was successfully prepared. APT-SBA-15@Zn2+ was found to be a fluorescent and ratiometric probe with remarkable selectivity and sensitivity. In the presence of TCs, the fluorescence intensity of APT–SBA–15@Zn2+ at 447 nm quenched and a new fluorescence emission appeared at 521 nm (or 512 nm), which was due to the strong interaction between TCs and Zn2+ that led to the decomposing of APT–SBA–15@Zn2+ and the formation TCs-Zn2+ complexes. The fluorescent intensity ratio at 521 nm (or 512 nm) and 447 nm versus the concentration of tetracycline (or oxytetracycline) displayed good linear relationships, realizing the ratiometric detection of TCs which can avoid interferences from background and external factors. The detection of tetracycline and oxytetracycline was limited to 76.4 and 76.2 nM, respectively.

Interfacial co-assembly strategy towards gradient mesoporous hollow sheet for molecule filtration

Gradient porous structures enable the fast capillary-directed mass transport and enhance the chemical reaction rate with optimal efficiency and minimal energy consumption. Rational design and facile synthesis of functional mesoporous materials with sheet structure and gradient mesopores still face challenges of stacked structures and unadjustable pore sizes. Herein, an interfacial co-assembly strategy for gradient mesoporous hollow silica sheets is reported. The modulated oil-water interface allows the assembly of gradient mesoporous silica layers on the water-removable ammonium sulfate crystals. The obtained mesoporous silica layers possess narrow pore size distributions (~2.2 nm and ~6.6 nm). Owing to the good mono-dispersity, sheet structure and proper pore size, the designed gradient mesoporous hollow silica sheets can serve as flexible building blocks for fabricating nanoscale molecule filtration device. Experiments reveal that the obtained nanofiltration device shows remarkable gradient rejection rates (range from 23.5 to 99.9%) for molecules with different sizes (range from 1.2 to 4.4 nm).

Synthesis of LiTiO2 Nanocrystals/Ordered Mesoporous Carbon Composite Hosts for High‐Performance Lithium–Sulfur Batteries

Metal oxide nanocrystals/mesoporous carbon composite materials are promising in the energy storage field. However, the construction of stoichiometric ternary nanocrystals‐functionalized mesoporous carbon materials remains a great challenge. Herein, the synthesis of ultradispersed and ultrasmall LiTiO2 nanocrystals/ordered mesoporous carbon composites via a chelation‐mediated multicomponent coassembly strategy is reported. In this case, the self‐assembly into ordered mesostructures and the crystallization of nanoparticle processes can be decoupled by the molecular chelate strategy where citrate ligands can effectively inhibit the hydrolysis and phase separation of metal oxide precursors and confine the crystallization into nanocrystals without aggregation. The obtained 33%‐LiTiO2–OMC composites present a high specific surface area (≈912 m2 g−1), a large pore volume (≈0.62 cm3 g−1), a uniform pore size (≈4.1 nm), and ultradispersed LiTiO2 nanocrystals (≈3 nm). When loading 60% sulfur, the composites exhibit a high reversible capacity (966 mAh g−1 after 100 cycles at 0.5C), an excellent rate capacity (700 mAh g−1 at 5C), and a long‐term cycling performance (63% retention after 1000 cycles at 5C). This method is very simple and reproducible, which paves a new way for the design and synthesis of functional mesoporous materials.

Functional mesoporous materials in clean energy: an interview with Dongyuan Zhao

ABSTRACT National Science Review invited Prof. Dongyuan Zhao of Fudan University for an interview focusing on his team's renowned research on functional mesoporous materials and energy-related applications. Prof. Zhao is a professor of chemistry and materials science, and a member of the Chinese Academy of Sciences. He received his PhD in chemistry from Jilin University in 1990. He has since focused his research on the synthesis and structure of porous materials and molecular sieves. His team received a first-tier national science award in 2021 for their contribution to the research and development of mesoscopic materials. They discovered a method of synthesizing mesoporous organic polymers and carbonaceous materials using organic-organic self-assembly. This work was published in 2005 and since then it has turned into a vibrant new field of more than 40 000 publications so far. His team has named more than 20 of their inventions after Fudan University: the FDU mesoporous series.

Morphology-Controlled Mesopores with Hydrophilic Pore Walls from Triblock Copolymers

We report a facile approach that can simultaneously control the morphology and surface chemistry of mesoporous materials from triblock copolymers. By doping phosphotungstic acid (PW), the self-assembled structures of polystyrene–poly(ethylene oxide)–polylactide (PS–PEO–PLA, SEL) triblock copolymer can be tuned. Besides core–shell cylinders and lamellae, disordered bicontinuous structures can be achieved in SEL/PW composites. After etching with NaOH, PLA domains and PW additive are removed simultaneously, giving mesoporous PS monoliths with controlled morphologies and PEO-coated pores. Also, we demonstrated that the prepared porous PS monoliths can be used as templates to fabricate inorganic nanostructures. This work provides new insight into the fabrication of functional mesoporous materials.

Utilization of waste from the silicon carbide grinding sludge and stone sludge as source of silicon aluminum for the synthesis of the amine functional mesoporous humidity control material

Utilization of waste from the silicon carbide grinding sludge and stone sludge as source of silicon aluminum for the synthesis of the amine functional mesoporous humidity control material

One-pot synthesis of mesoporous silicas supported Cu single-atom and CuO nanoparticles for peroxymonosulfate-activated degradation of tetracycline over a wide pH range

Peroxymonosulfate activated heterogeneous Fenton-like catalytic reactions are promising in degradation of recalcitrant pollutants. Mesoporous silicas supported high-dispersion Cu species, as a kind of conventional heterogeneous catalysts for extensive applications, are rarely studied for their degradation efficiency in peroxymonosulfate-triggered reactions. In this work, one-pot incorporation method was employed to generate simultaneously Cu single-atom, Cu nanoparticles in mesoporous silicas (like the sample of Cu/Si-3 with 0.68 wt% of Cu) using sodium copper chlorophyllin as Cu source by calcining directly in air atmosphere. Several characterizations confirm the coexistence of Cu single-atom, Cu nanoparticles and mesopore with uniform size distribution. Activated by peroxymonosulfate, Cu/Si-3 was found to be efficient in degradation of tetracycline throughout a wide pH range of 2–11. The radicals of S O 4 g − , ⋅ O H and O 1 2 played their role in the degradation reaction. The underlying catalytic mechanism of the Fenton-like reaction was speculated on the basis of analysis of reactive oxygen species. This work has important implication in reasonable design and fabrication of catalysts with high-dispersion metal and controllable synthesis of functional mesoporous materials, as well as in proper disposal of recalcitrant pollutants including tetracycline. • Composite of Cu single-atom and CuO nanoparticles simultaneously generated by one-pot synthesis under air atmosphere. • Successful preparation of mesoporous materials with uniform size distribution. • Cu single-atom catalysts obtained by calcination without protection of inert gas. • The obtained highly dispersed Cu species favourable in degradation of tetracycline. • The catalyst's wide working pH window of 2–11.

Interfacial Assembly and Applications of Functional Mesoporous Materials.

Functional mesoporous materials have gained tremendous attention due to their distinctive properties and potential applications. In recent decades, the self-assembly of micelles and framework precursors into mesostructures on the liquid-solid, liquid-liquid, and gas-liquid interface has been explored in the construction of functional mesoporous materials with diverse compositions, morphologies, mesostructures, and pore sizes. Compared with the one-phase solution synthetic approach, the introduction of a two-phase interface in the synthetic system changes self-assembly behaviors between micelles and framework species, leading to the possibility for the on-demand fabrication of unique mesoporous architectures. In addition, controlling the interfacial tension is critical to manipulate the self-assembly process for precise synthesis. In particular, recent breakthroughs based on the concept of the "monomicelles" assembly mechanism are very promising and interesting for the synthesis of functional mesoporous materials with the precise control. In this review, we highlight the synthetic strategies, principles, and interface engineering at the macroscale, microscale, and nanoscale for oriented interfacial assembly of functional mesoporous materials over the past 10 years. The potential applications in various fields, including adsorption, separation, sensors, catalysis, energy storage, solar cells, and biomedicine, are discussed. Finally, we also propose the remaining challenges, possible directions, and opportunities in this field for the future outlook.

Modulation of the Activity of Gold Clusters Immobilized on Functionalized Mesoporous Materials in the Oxidation of Cyclohexene via the Functional Group. The Case of Aminopropyl Moiety.

Gold nanoclusters and isolated gold atoms have been produced in a two-liquid phase procedure that involves a solution of gold in aqua regia and rosemary essential oil as organic layer. These gold entities have been immobilized on the ordered mesoporous silica material SBA-15 functionalized with different amounts of aminopropyl groups. The resulting materials have been characterized by XRD, N2 adsorption, chemical analysis, TGA, 29Si MAS NMR, 13C CP/MAS NMR, UV-vis spectroscopy, XPS, and STEM. The Au-containing materials retain the ordering and porosity of the pristine support. Gold content varies in the range of 0.07–0.7 wt% as a function of the specific immobilization conditions, while STEM evidences the presence of isolated gold atoms. XPS shows a shift of the Au 4f BE toward values lower than those of metallic gold. The catalytic activity in the oxidation of cyclohexene with molecular oxygen at atmospheric pressure parallels the Au content of the aminopropyl-SBA-15 supports. This activity is higher than that of analogous Au entities immobilized on SBA-15 functionalized with thiol or sulfonate groups, the activity decreasing in the order Au-NH2 > Au-SO3− > Au-SH. This behavior has been attributed to differences in the interaction strength between the functional group and the Au entities, which is optimum for the aminopropyl groups.

Pyridine Schiff Base Functionalized Mesoporous Channels as Fluorescent Detection of Silver Ions in Aqueous Medium

A novel fluorescent probe based on functional mesoporous material (denoted as SBA-KH-2py) with high sensitivity and selectivity of detecting silver ions (Ag + ) was designed and prepared by immobilizing (4-nitro-2-((pyridin-2-ylmethylene) amino) aniline (denoted as 2py-Schiff base) within the channels of mesoporous material. The 2py-Schiff base was successively loaded within the framework of mesoporous material by the organic silane coupling agent, and the ordered channels were still retained. With the increasing loading amounts of Schiff base, the fluorescence intensities of functional materials also were enhanced in the fluorescent spectra excited by the same wavelengths. Especially, the material SBA-KH-20%-2py possesses the strongest fluorescence intensity. Moreover, in the recognition experiments, it can definitely distinguish Ag + ions in aqueous solutions, which shows the excellent selectivity and high sensitivity.

CO2 methanation over Ni/Mg@MCM-41 prepared by in-situ synthesis method

A series of xMg@MCM-41(x=0, 0.05, 0.1) functional mesoporous materials were synthesized by a novel in-situ one pot method and then were used as supports for Ni based catalysts. The results of XRD and TEM show that when the amount of Mg/Si (molar ratio) is 0.05, Mg@MCM-4 with a regular and ordered mesoporous structure is synthesized where Mg is introduced into the framework of MCM-41. Introducing Mg into the framework of the support can significantly enhance the basic properties of the catalyst, thus promoting the adsorption and activation of CO2. The catalysts prepared in the experiments all have good thermal stability and catalytic activity. Among them, Ni/0.05Mg@MCM-41 showed the best low temperature reaction activity in the CO2 methanation reaction.

Recent progress on functional mesoporous materials as catalysts in organic synthesis

The heterogenization of homogeneous catalysts has attracted great attention owing to their increasing environmental and economic considerations. Mesoporous materials are a kind of attractive candidates due to their unique structural features, such as high surface areas, uniform and tunable pore sizes and shapes, large pore volumes, and easy to be functionalized. Therefore, mesoporous materials have been used as catalysts or their supports for homogeneous catalysis in the past decades. This review concerns the very recent development in this area, including the catalyst design, the types of active species, and the reaction catalyst by this kind of catalysts. Mesoporous catalysts can be classified as supported catalyst and bulk one. The supported catalyst includes active site in the pore wall framework, the active site on the pore wall surface, and the active site encapsulated in the mesopores. The bulk one can be directly used as catalyst, which includes metal oxides and carbon nitrides. Next, four different types of active sites, nanoparticles, highly distributed metals, anchored organic catalysts, and immobilized enzymes, are summarized in this review. Then five types of organic reactions are summarized. With the development of electrochemistry in organic synthesis in recent years, a brief outlook is also discussed.

Performance of the MCM-41-NH2 Functionalized Mesoporous Material Synthetized from the Rice Husk Ash on the Removal of the Polycyclic Aromatic Hydrocarbons

In this work, the authors propose of the synthesis of a new adsorbent functionalized mesoporous material (MCM-41-NH2 (RHA)) from the Brazilian rice husk for the removal of the polycyclic aromatic hydrocarbons (PAHs). The new MCM-41-NH2 (RHA) was characterized using FTIR, TGA, SAXS, and N2 adsorption-desorption analyses, on the other hand, the removal experiments were performed to determine the adsorption parameters, such as the initial concentration, MCM-41-NH2 (RHA) amount, pH, time, and temperature. The hydrothermal/post-grafting methods were sustainable for the synthesis of the MCM-41-NH2 (RHA) functionalized mesoporous material, the same presented the main characteristic absorption bands of the mesoporous arrays, hexagonal mesostructure, type IV isotherms with H1 hysteresis, high surface area, and good thermal stability. Assessment of the adsorption of the MCM-41-NH2 (RHA) showed that the amount of the PAHs mixture adsorbed increased with the increase of the initial concentration, MCM-41-NH2 (RHA) amount, and contact time, as well as, the pH = 5.6 was the best for the removal of the PAHs mixture. However, the temperature variation did not significantly alter the efficiency of the MCM-41-NH2 (RHA). The removal percentage of the PAHs were 81.20, 94.25, 94.87, and 98.14% for the naphthalene (Nap), benzo[a]pyrene (B[a]P), benzo[k]fluoranthene (B[k]F), and benzo[b]fluoranthene (B[b]F), respectively, with the equilibrium time of approximately 200 min for the all PAHs. In addition, the adsorption equilibrium followed the nonlinear pseudo-second-order and the Langmuir models, which describe satisfactory adsorption of the PAHs mixture on the MCM-41-NH2 (RHA) functionalized mesoporous material.

Removal of Cr(VI) from Wastewater of the Tannery Industry by Functionalized Mesoporous Material

A previously synthesized PABA-MCM-41 mesoporous material was used to remove Cr(VI) in leather samples. The optimization step was performed using univariate method for the following variables: pH, concentration of Cr(VI) standard, time, dose, and reuse of PABA-MCM-41 adsorbent material. The optimum pH of the adsorption process was equal to 3, the adsorbed amount (qe) increased with the increase in initial Cr(VI) concentration, as well as with increase of PABA-MCM-41 dose. The adsorption efficiency increased with the time and the equilibrium was reached in approximately 80 min, with maximum adsorption efficiency of 98.3%. The adsorption kinetic and equilibrium data were better fitted with the non-linear pseudo-first order and Freundlich models, respectively. Leather samples presented Cr(VI) concentration values above of the maximum values regulated by European Union. The PABA-MCM-41 presented Cr(VI) removal percentage values for the real samples between 97.5–99.2%. The PABA-MCM-41 had not matrix effect in the adsorption process, and thus allowing its application in wastewater contaminated with heavy metals.

Recent Advances in Preparation and Application of Functionalized Mesoporous Materials

Functionalized mesoporous materials are widely used in the environmental field due to their excellent adsorption and catalytic properties. The materials with different functions are obtained by modifying mesoporous materials. In this paper, the preparation methods of functional mesoporous materials with functional groups, metal doping and acid modified were presented. This review focused on the main features and applied prospects of functionalized mesoporous materials under three producing methods. Recent advances of functionalized mesoporous materials in the fields of adsorption and catalysis have been summarized. Adsorption mainly refers to the treatment of heavy metals, organic contaminant, dyestuff and CO2. Finally, the trends and application foreground of functionalized mesoporous materials were elaborated in this paper, which provided reference and guidance for the development of functional mesoporous materials.

Latest progress on the typical mesoporous Si-based solid acid catalysts

Serious environment and safety issues by the wide application of inorganic mineral acids have attracted worldwide attention from fundamental science and application point of view. Under such circumstances, the development of the solid acid catalysts is a very hot topic currently. The ideal solid acid catalysts possess appropriate Bronsted and Lewis acidic nature, good porosity, high stability and unique morphology. Among them, the morphological nanostructure of catalysts is one of the important factors that can have a profound influence on their catalytic performance. Compared with a number of other supports of the solid acid catalysts, the silica-based materials are considered as promising candidates because of their diverse composition, physicochemical property and morphology as well as excellent porosity property. Among them, mesoporous silica-based materials possess lager pore compared with the microporous silica materials (e.g., ZSM-5, H-beta, etc.). They enable to catalyze reactions efficiently involving bulky substrates and/or products, and facilitate mass transfer. Meanwhile, the larger pore favors the dispersion of the active sites and hinders the accumulation of coke on the surface to avoid pore blocking. As a result, one of the important strategies to prepare novel solid acid catalysts is to immobilize the active sites on mesoporous silica materials. The as-prepared mesoporous silica-based solid acid catalysts have shown great potential for application in the field of environment, energy and industrial catalysis. In this paper, the latest progress on the morphology-controlled preparation of mesoporous silica−based materials and their applications in catalysis are summarized. In the case of the silica-based materials, it can be dated back to the early 1990s, and Mobil Company synthesized various M41S materials firstly (MCM-41, MCM-48 and MCM-50) by using the alkyl quaternary ammonium salt cationic surfactant as the template agent. Compared with the amorphous silica materials, M41S possess ordered mesoporous structure, uniform pore size (2‒5 nm), large pore volume and BET surface area (1000 m2 g-1). Subsequently, various SBA materials (such as SBA-15 and SBA-16) with large pore size were prepared successfully. It has attracted wide attention to functionalize the silica materials by incorporating the active sites and maintaining the morphological structure. With the development of silica-based materials, periodic mesoporous organosilicas (PMO) were synthesized by surfactant-directed sol-gel method, which opened a new pathway to prepare functional mesoporous silica materials. Up to now, a number of functionalized organosilica materials have been reported and exhibited great potential in the fields of catalysis, sensing, chromatography analysis, metal adsorption and bio-pharmacy etc. Herein, the mesoporous silica-based solid acid catalysts by the morphology-controlled preparation of functionalized organosilicas showed highly ordered, tubular or hollow spherical nanostructure by P123-directed sol-gel co-condensation. The as-prepared mesoporous silica-based solid acid catalysts possessed hydrophobic surface, excellent porosity property and strong Bronsted acidic nature. Moreover, the catalysts with well-defined morphology exhibited high catalytic performance for synthesis of the biomass-derived platform molecules or high value-added chemicals. Owing to the accelerated diffusion, transmission and improved accessibility of substrates to active sites, the mesoporous silica-based solid acid catalysts with hollow nanosphere morphology showed the highest activity compared with the tubular or ordered analogues. On the other hand, the covalent bond between active sites and silica framework can avoid the leaching issue of the solid acid catalysts. In addition, the hydrophobic character of alkyl-containing organosilica can reduce acid sites deactivation associated with adsorption of polar byproducts, which can improve the stability of as-prepared catalysts. To summarize, this review aims to provide important reference value for development of novel solid acid catalysts.

IR spectroscopy study of SBA-15 silicas functionalized with the ethylthiocarbamidepropyl groups and their interactions with Ag(I) and Hg(II) ions

Mesoporous structure of silica is determined by the type of template, but the introduction of functional groups during the synthesis has additional influence. The structure of SBA-15 may be violated by the introduction of long functions, such as ≡Si(CH2)3NHC(=S)NHC2H5. These ethylthiocarbamidepropyl groups can form complexes with metal ions in thiol or thione tautomeric forms. We determined that the 2D hexagonal p6 mm structure is preserved for SBA-15 with thiourea groups at maximal TEOS:trifunctional silane ratio (mol) = 10:2, which was confirmed by TEM and by the presence of an intense reflex in the small-angle region of diffractograms of the final product. It was shown that the obtained sorbents possess high kinetic characteristics. The experimental data fit pseudo-second-order kinetic equation, but the rate constants depend on the content of functional groups in the surface layer. Template Pluronic P-123 defines the porosity of functional mesoporous silica materials even at increasing content of trifunctional silane in the initial solution. Infrared spectroscopy analysis showed that thione form of thiourea ligand is prevalent on the surface of pores of mesoporous samples. However, during the sorption of silver(I) ions, there are both thione and thiol forms on the surface. Thione form is transformed into thiol with increasing concentration of mercury(II) ions in the sorption solution. Adsorption experiments showed that the SBA-15 silicas functionalized with ethylthiocarbamidepropyl groups had high selectivity for silver(I) ions and could concentrate Ag(I) ions from metal ions mixture at pH ~ 2.

Preparation of chitosan/MCM-41-PAA nanocomposites and the adsorption behaviour of Hg(II) ions.

A novel functional hybrid mesoporous composite material (CMP) based on chitosan and MCM-41-PAA was reported and its application as an excellent adsorbent for Hg(II) ions was also investigated. Innovatively, MCM-41-PAA was prepared by using diatomite and polyacrylic acid (PAA) with integrated polymer–silica hybrid frameworks, and then CMP was fabricated by introducing MCM-41-PAA to chitosan using glutaraldehyde as a cross-linking agent. The structure and morphology of CMP were characterized by X-ray diffraction, Fourier transform infrared spectra, thermogravimetric analysis, scanning electron microscopy and Brunauer–Emmett–Teller measurements. The results showed that the CMP possessed multifunctional groups such as –OH, –COOH and –NH2 with large specific surface area. Adsorption behaviour of Hg(II) ions onto CMP was fitted better by the pseudo-second-order kinetic model and the Langmuir model when the initial Hg(II) concentration, pH, adsorption temperature and time were 200 mg l−1, 4, 298 K and 120 min, respectively, as the optimum conditions. The corresponding maximum adsorption capacity could reach 164 mg g−1. According to the thermodynamic parameters determined such as free energy, enthalpy and entropy, the adsorption process of Hg(II) ions was spontaneous endothermic adsorption.

Facile synthesis of copper(II)-decorated functional mesoporous material for specific adsorption of histidine-rich proteins

The Cu2+-decorated functional mesoporous material was fabricated by thermally initiated free-radical polymerization of octavinyl polyhedral oligomeric silsesquioxane. It was used as adsorbent for highly specific separation of histidine (His)-rich proteins in blood and cell lysate based on immobilized metal affinity chromatography. The functional mesoporous material (named as PPOSS-IDA-Cu2+) was characterized in detail and its selectivity and binding capacity were evaluated using a His-rich protein (bovine hemoglobin, BHb) and other proteins (bovine serum albumin, myoglobin, lysozyme and horseradish peroxidase) containing fewer surface-exposed His residues as model proteins. The results indicated that PPOSS-IDA-Cu2+ exhibited large specific surface area and good selective adsorption ability and the maximum adsorption capacity for BHb was 3150mgg−1. Moreover, PPOSS-IDA-Cu2+ had excellent recyclability and the adsorption capacity of the reused material for BHb remained almost unchanged after six cycles. In addition, PPOSS-IDA-Cu2+ not only showed excellent performance for the removal of highly abundant hemoglobin in human blood, but also can be a good adsorbent for the enrichment of proteins in cell lysate. It was the first time to explore the application of Cu2+-decorated functional material as an adsorbant for the separation of proteins in cell lysate. This approach can be combined with other techniques which can remove or deplete highly abundant proteins from real biological samples to obtain more comprehensive data about low abundant His-rich proteins in proteomic analysis.